Karrin Weisenthal's research while affiliated with Harvard Medical School and other places

Publications (7)

Article
Full-text available
Epigenetic modification of chromatin is involved in non-malignant pituitary neoplasia by causing abnormal expression of tumor suppressors and oncogenes. These changes are potentially reversible, suggesting the possibility of targeting tumor cells by restoring the expression of epigenetically silenced tumor suppressors. The role of the histone deace...
Preprint
Background: Police action can increase risky substance use patterns by people who use drugs (PWUD), but it is not known how increased police presence affects utilization of low-barrier substance use disorder bridge clinics. Increased police presence may increase or decrease treatment-seeking behavior. We examined whether Operation Clean Sweep (OCS)...
Article
Objective Kidney stones are common, tend to recur, and afflict a young population. Despite evidence and recommendations, adoption of reduced-radiation dose CT (RDCT) for kidney stone CT (KSCT) is slow. We sought to design and test an intervention to improve adoption of RDCT protocols for KSCT using a randomized facility-based intervention. Methods...
Article
Full-text available
Objectives An increasing number of medical schools are incorporating point‐of‐care ultrasound (POCUS) into preclinical and clinical curricula. The ultimate effect of this teaching is unclear, and there has been no distinct link between ultrasound (US) learning and existing standardized student assessments. Additionally, neither optimal timing nor m...
Article
Purpose To determine if the use of reduced-dose computed tomography (CT) for evaluation of kidney stones increased in 2015-2016 compared with that in 2011-2012, to determine variability in radiation exposure according to facility for this indication, and to establish a current average radiation dose for CT evaluation for kidney stones by querying a...
Article
Purpose Over one million patients seek care in an Emergency Department (ED) for kidney stones annually, but a minority require admission or urologic procedure. We aim to describe predictors of hospital admission or urologic intervention. Materials and Methods This secondary analysis of prospective data includes ED patients with CT-confirmed obstru...
Article
Despite being a major stakeholder in the U.S. health care system, the medical community has remained relatively mute in the debate over the future of the Patient Protection and Affordable Care Act (ACA). If the ACA were repealed, tens of millions of Americans would be in danger of losing their insurance, resulting in a significant increase in morta...

Citations

... 6 A 2010 study found that 8% of patients who underwent CT colonography had asymptomatic urolithiasis. 6 Ultra lose dose CT (ULD-CT) protocols have also been developed specifically for kidney stone screening and surveillance [7][8][9] and ULD-CT can be lower cost than renal ultrasound. 8 A 2005 study estimated that the total direct and indirect costs of nephrolithiasis was approximately $4.5 billion in 2000 in the United States and growing each year. ...
... for students not in the curriculum, p = 0.081). Liu et al. also reported finding no difference associated with participation in the US curriculum for USMLE Step 1 [27]. Contrary to our results, Liu et al. found no difference in anatomy exam scores, but did find an association with improved assessment of physical examination skills [27]. ...
... Rob et al., for example, reporting on a systematic review of different scan protocols, defined radiation doses of ≤3.5 mSv as "low-dose" and ≤1.9 mSv as "ultra-low-dose" [15]. Weisenthal et al., also conducting a systematic review, defined the term "reduced-dose CT" as a CT scan with a dose length product (DLP) of 200 mGy*cm or less [16]. ...
... With the global incidence and prevalence of urolithiasis increasing over consecutive decades, the importance of effective and efficient care is paramount for sustainability. 1,5 By examining potential or established barriers to managing acute ureteric colic, we can minimise strain on healthcare providers while maintaining patient outcomes. Thus far, prior literature has not examined or outlined the various potential components that conceptually make up the barriers to ureteric colic management. ...
... Many physicians became vocal to protect the Affordable Care Act; indeed, medical students called on their more senior mentors to show them the way regarding high-effort advocacy such as opinion writing and meeting with lawmakers regarding the Affordable Care Act (Levinsohn et al., 2017). Clearly, physician advocacy is not only valuable for the changes we can make to the health of the public but also for the example we set for the next generation of doctors. ...