Karin Lisspers's research while affiliated with Uppsala University and other places

Publications (13)

Article
Full-text available
Respiratory diseases remain a significant cause of global morbidity and mortality and primary care plays a central role in their prevention, diagnosis and management. An e-Delphi process was employed to identify and prioritise the current respiratory research needs of primary care health professionals worldwide. One hundred and twelve community-bas...
Conference Paper
Background: Increased blood eosinophils (B-Eos) are common in asthma and correlate with asthma attacks. The role of blood eosinophilia in COPD and its relation to acute exacerbations of COPD (AECOPD) have been less studied. Method: Subjects from the TIE-study with spirometry-verified COPD and CRP levels < 10 mg/ml were included. Subjects performed...
Article
Background: Though the GOLD recommendations state that chronic obstructive pulmonary disease (COPD) should be diagnosed using spirometry, this is not always done in practice. Objective: To assess differences in clinical and economic outcomes in COPD patients in whom the diagnoses included or did not include use of spirometry. Methods: Medical recor...
Article
Background: Identifying comorbidities in chronic obstructive pulmonary disease (COPD) may lead to improved disease management, survival and costs. Objective: To compare comorbidities and associated healthcare use between COPD and non-COPD patients. Methods: COPD patients' medical records data from primary care in Sweden were linked to primary and s...
Article
Background: For effective drug delivery it is essential to ensure that patients can use their inhaler devices. Patients' inhaler technique should be monitored at each visit according to guidelines.The TIE-study is a prospective multi-centre study in primary and secondary care in Sweden to identify predictors of exacerbations in chronic obstructive...
Conference Paper
Exhaled NO (FENO50) is frequently used in asthma to assess airway inflammation but less established in COPD. The TIE-study is a prospective multi-centre study to identify predictors of exacerbations in COPD patients. One specific aim was to assess FENO50 in patients with correlations to complete blood count, symptoms and physical ability at the inc...
Article
Introduction: Multidisciplinary rehabilitation is well-documented in all stages of COPD. Aims: To investigate the availability and utilisation of rehabilitation and the characteristics of COPD patients receiving rehabilitation, in primary and secondary care in mid-Sweden. Materials and methods: Structural questionnaires to 14 hospitals and 54 pri...
Article
Aim: To determine the prevalence of a range of comorbidities in COPD patients and their associations with quality of life and COPD symptoms in primary care patients different settings across Europe. Method: Cross-sectional analyses of nine primary care datasets from seven European countries with in total 125,231 diagnosed COPD patients. The impact...
Article
Aim: To analyse the course of quality of life (QoL) and asthma control between 2005 and 2012 in older asthmatics and compare these outcomes with younger asthmatics. Method: 747 randomly selected asthma patients (age 18-75) from primary and secondary care completed two questionnaires seven years apart. MiniAQLQ was used to assess QoL and asthma con...
Article
Background: Chronic obstructive pulmonary disease (COPD) confers several direct and indirect costs. Objective: To retrospectively assess healthcare utilisation and societal costs associated with COPD. Methods: Primary care medical records data from Swedish COPD patients were linked with primary and secondary care national registries data, includi...
Article
Background: Early chronic obstructive pulmonary disease (COPD) diagnosis may lead to improved disease management and reduced costs. Objective: To assess the clinical and economic impact of early vs late stage COPD diagnosis. Methods: Medical records data were collected from COPD patients in Swedish primary care centers and then linked to primary an...
Article
Aim: To describe the prevalence of comorbidities and mortality in a Swedish asthma population. Method: Overall, 35,328 patients (mean age 39 years, 59% females) with asthma (ICD-10 J45) were included. Medical records data from Swedish primary care were linked to National hospital, drug, and cause of death registries. Comorbidities (cumulative prev...

Citations

... Prioritizing primary care respiratory research needs have been identified by the International Primary Care Respiratory Group for primary care health professionals worldwide. [21] However, a prioritized research agenda should encapsulate all relevant themes related to respiratory diseases in the context of the global fight against NCDs, infectious respiratory diseases, and the pandemic of COVID-19. This requires both respiratory-diseasetargeted interventions and comprehensive NCD programs with an emphasis on health promotion, prevention, and treatment. ...
... In addition, according to the form of presentation, the parameters should be divided into two more types: quantitative and qualitative. In work [8], it is shown that the multifactorial nature of interaction and an unlimited number of factors characterize medical diagnostics and rehabilitation recovery as one of the types of a complex biological-socio-economic process. The process of recovery and assessment of the socio-economic determinants of health is rapidly volatile and requires the use of intelligent information systems to build a diagnosis and restorative prescription and is rapidly volatile [9]. ...
... Asthma showed a statistically significant positive association only with hypertension, heart failure and cerebrovascular diseases, not with other CVDs. In the literature, however, CVDs are the second most common comorbidities of asthma [22], so we had expected a positive association between asthma and each of the CVDs. This might be due to lack of questioning of the predisposing and associated factors such as smoking habits, family history and environmental factors. ...
... 1 COPD is characterized by progressively worsening shortness of breath, wheezing, mucus production, and physical fatigue from participating in the least demanding activities. 2 Its timely detection and selfmanagement have shown to reduce the occurrence of breathing exacerbations, hospitalizations, and complications due to comorbidities (eg, mental distress). 3,4 Unfortunately, millions are living with COPD but have yet to be diagnosed. 5 The opportunity to diagnose COPD is generally missed in about 70% 3 and 85% 6 of adults. ...
... According to some studies, the relationship between the number of comorbidities and the related public health costs is exponential, with a tendency for the costs to double with each additional disease in a given individual 11 . In particular, previous studies on patients with COPD found that comorbidities make an important contribution to the total costs 10,12 . Often amounting to more than the costs due to the respiratory condition itself 13,14 . ...
... As the mechanisms of depression in COPD are still not fully understood, declining health status, frailty, aging, systemic inflammation, the impact of smoking, and hypoxemia on brain function possibly have a substantial effect on the development of reactive depression [11,24]. Different researches report a higher prevalence of diabetes mellitus in COPD patients than other populations [20,24,29,55]. In our study, COPD was associated with increased odds of diabetes and kidney diseases, but the prevalence of diabetes was not higher than in other diseased Lithuanians. ...
... Coordinating with the team and with clients to set treatment goals that are meaningful to clients illustrates one of the ways that participants connected effective team work with CC. This connection resonates with the scholarly literature as well [35][36][37]. In this section, we illustrate the connection between work in teams and CC and practice as perceived by HCP participants. ...
... Conventional approaches in respiratory medicine are gradually incorporating interdisciplinary frontiers of research [1][2][3][4] to improve the quality of healthcare and life. During respiration many trace concentrated (∼parts per billion to parts per trillion by volume range) volatile organic compounds (VOCs) are exchanged between blood and breath. ...
... Regardless of the type of inhaler device, patients need training on the correct inhaler technique as it has been shown that over 50% of patients do not use their inhaler devices correctly. [5][6][7] In Jordan, it has been estimated that only 20% of asthmatic patients are able to use their inhalers correctly. 8 Furthermore, inappropriate inhaler technique is associated with poor asthma outcomes and avoidable treatment costs. ...
... Furthermore, IL-8, released by injured epithelial cells, and leukotrienes (LTB 4 ), released by agitated macrophages, are major neutrophil chemoattractants in the lungs of patients with COPD. 53 Patients with high levels of IL-8 are more susceptible to emphysema. 54 According to Tulah et al, 55 polymorphisms within genes that control LTB 4 production could determine baseline FEV 1 and FEV 1 /FVC, as well as susceptibility to airflow obstruction in smokers. ...