Kalle Salminen’s research while affiliated with Fuzhou University and other places

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Publications (30)


A novel electrochemical sensor based on La-MOF@C60-β-cyclodextrin composite for sensitive detection of dichlorophen in lake and tap water
  • Article

February 2025

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10 Reads

Journal of Environmental Chemical Engineering

Yu Xie

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Wei Zhou

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Jia-Wen Yin

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[...]

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The SEM images of planar (A) and porous (B) electrodes, the CV plots of planar and porous electrodes in 0.5 M H2SO4, scan rate 0.1 V/s, and (D) the anti-fouling principle of porous electrodes, red and blue dots represent redox species and proteins
Optimization of the aptamer concentration for (A) planar and (B) porous electrodes. C The signal gain of planar and porous electrodes under the optimal aptamer concentration at different frequencies (cocaine concentration: 3.0 μM)
A Relationship between signal gain and temperature at the porous electrode with 3.0 μM cocaine, (B) the binding curve of the EAB sensor at 25℃ and 10℃
The SWV peak currents at different frequencies with and without 3.0 μM cocaine at 25 °C (A) and 10 °C (B) in the working buffer. C Signal gain of the cocaine sensor with 3.0 μM cocaine at 25 °C and 10 °C. Normalized peak currents at 25 °C (E) and 10 °C (F), dash line indicates the position of the highest normalized signal. The shaded areas indicate the standard deviation from three independently manufactured sensors
SWV plots of the cocaine sensor with different cocaine concentrations at 25℃ (A) and 10℃ (B) in the working buffer. Binding curves (C), linear (D) and logarithmic (E) relationship between signal gain and the cocaine concentration at 25℃ and 10℃

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Rapid nanomolar detection of cocaine in biofluids by electrochemical aptamer-based sensor with low-temperature effect for drugged driving screening
  • Article
  • Publisher preview available

August 2024

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56 Reads

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1 Citation

Microchimica Acta

Cocaine is one of the most abused illicit drugs, and its abuse damages the central nervous system and can even lead directly to death. Therefore, the development of simple, rapid and highly sensitive detection methods is crucial for the prevention and control of drug abuse, traffic accidents and crime. In this work, an electrochemical aptamer-based (EAB) sensor based on the low-temperature enhancement effect was developed for the direct determination of cocaine in bio-samples. The signal gain of the sensor at 10 °C was greatly improved compared to room temperature, owing to the improved affinity between the aptamer and the target. Additionally, the electroactive area of the gold electrode used to fabricate the EAB sensor was increased 20 times by a simple electrochemical roughening method. The porous electrode possesses more efficient electron transfer and better antifouling properties after roughening. These improvements enabled the sensor to achieve rapid detection of cocaine in complex bio-samples. The low detection limits (LOD) of cocaine in undiluted urine, 50% serum and 50% saliva were 70 nM, 30 nM and 10 nM, respectively, which are below the concentration threshold in drugged driving screening. The aptasensor was simple to construct and reusable, which offers potential for drugged driving screening in the real world.

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Citations (12)


... Lateral-flow immunoassay using electrochemical transducers is a rapid method for the identification of THC which is able to detect it in an analysis time of 6 min with a detection limit of 1.3 ng/mL [97]. Another electrochemical method using an aptasensor for the detection of THC in saliva showed a one-minute identification [98] with a detection limit of 5 nM in serum, 5 nM in urine and 10 nM in 50% diluted saliva [99]. Despite the fact that these methods are very rapid and have a nanomolar detection limit, they cannot exclude false positive reactions during routine determinations, especially because they do not identify metabolites in the same run. ...

Reference:

Cannabis: Zone Aspects of Raw Plant Components in Sport—A Narrative Review
Rapid nanomolar detection of Δ9-tetrahydrocannabinol in biofluids via electrochemical aptamer-based biosensor
  • Citing Article
  • February 2024

Analytica Chimica Acta

... Following this, the response for ketamine detection was observed at each concentration using CV and LSV. The aptamer-immobilized electrodes were employed to detect ketamine at various temperatures (15,25,35,45,55, 65 • C) and times (5 to 35 s), and the best cyclic response was observed. The target was detected using the electrodes that had been immobilized with the aptamer. ...

Rapid nanomolar detection of ketamine in biofluids based on electrochemical aptamer-based sensor for drugged driving screening within 30s
  • Citing Article
  • April 2023

Sensors and Actuators B Chemical

... Changing the concentration of redox-label modified aptamers is a key point in controlling the spacing of the aptamer [31]. Excessively high aptamer densities result in spatial site-blocking, which prevents target binding, while much lower aptamer densities make the signal undetectable [32]. Therefore, the aptamer concentrations at planar and porous electrodes were optimized (Fig. 2). ...

Real-Time Tunable Dynamic Range for Calibration-Free Biomolecular Measurements with a Temperature-Modulated Electrochemical Aptamer-Based Sensor in an Unprocessed Actual Sample
  • Citing Article
  • December 2021

Analytical Chemistry

... Cellulose derivative continued to be a topic of research interest according to its abundant, easy handling, biodegradation [1][2][3]. Carboxymethyl cellulose which is termed CMC, is one of famous examples of cellulose derivatives. Even it is considered as the most used cellulose derivatives in the industry. ...

Hot electron-induced electrochemiluminescence at cellulose derivatives-based composite electrodes
  • Citing Article
  • December 2018

Journal of Electroanalytical Chemistry

... In lignocellulose, this leads to a blueshift (Fig. 5c) and a decrease (Fig. 3a) in emission, as observed in the present study. 6. Phosphorescence was not examined in this study, but reported for cellulose by Grönroos et al. (2018). ...

Phosphorescence and fluorescence of fibrillar cellulose films
  • Citing Article
  • June 2018

... More recently, blends of polystyrene (PS) and PCL as a binder were investigated by our group and found to have much lower capacitance and faster electron transfer kinetics than PCL TPEs due to their surface morphology and enhanced edge plane characteristic [47] . SEM and electrochemistry data indicate PS TPE surfaces have lower roughness and more graphitic edge-plane rich features than PCL TPEs likely owing to aromatic nature of PS which allows interactions to the graphite surfaces through ππ interactions [48] . In addition, PS-based TPEs have been demonstrated to have enhanced electron transfer kinetics compared to previously reported PS electrodes [49][50][51][52] . ...

Immunoassay of C-reactive protein by hot electron-induced electrochemiluminescence at polystyrene-carbon black composite electrodes
  • Citing Article
  • June 2018

Electrochimica Acta

... Insulating polymer material surrounds the carbon black particles and enables electrons to be transported through the thin composite layer with very low IR-loss, and finally hot electrons to be emitted at the electrode/solution interface. The main advantage of these novel electrodes over traditional insulating thin-film covered electrodes is their insensitivity to composite layer thickness and composition of the film [9,15,21,22]. Compared to thin insulating film-coated electrode materials, such as aluminum or silicon, composite electrodes are found to have a more stable and reproducible HECL output in a wider pH range, and most importantly, without considerable background emission [15,23,24]. ...

Hot electron-induced electrochemiluminescence of calcein and calcein-Tb(III) complex at disposable oxide-covered aluminum and polyvinyl butyral-carbon black/metal composite electrodes in aqueous solutions
  • Citing Article
  • February 2018

Electrochimica Acta

... Solvated electrons, and hydrated electrons in water, are the chemist's perfect reducing agent in many ways. Recently, we made efforts to develop low-cost replacements [6,7] for chemically quite non-resistant oxide-coated aluminium electrodes [8][9][10] and typically a bit too expensive oxide-coated silicon electrodes [7,8] for hot electron injection into fully aqueous electrolyte solutions [1][2][3][4][5]. ...

Cathodic electrogenerated chemiluminescence of aromatic Tb(III) chelates at polystyrene-graphite composite electrodes
  • Citing Article
  • July 2017

Analytica Chimica Acta

... These added co-reactants generate oxidizing radicals upon one-electron reduction (e.g., peroxodisulphate, peroxodiphosphate or hydrogen peroxide) or in the case of azide, upon one-electron oxidation. Thus, both extremely strong oxidants and reductants are produced, and normally one-electron redox reactions not obtainable occur and the excitation of several types of label compounds are enabled [4,9]. There are two major excitation routes: one usually being clearly dominant, and sometimes both excitation routes are almost equally significant, mostly depending on the lifetime and the redox properties of all the radical species involved in the system in aqueous solution. ...

Hot electron-induced electrochemiluminescence at polyetherimide-carbon black-based electrodes
  • Citing Article
  • May 2017

Electrochimica Acta

... HECL has been studied with several electrode materials (e.g. Al/Al 2 O 3 , Si/SiO 2 , C/ C x O 1−x and Ta/Ta 2 O 5 ) [6] [9,20,21] and different electrode types such as integrated electrodes [12], microelectrodes with very sharp tips and minimal electrode surface areas [22] and metal/insulator/metal electrodes (e.g. Ta/Ta 2 O 5 /Pt) [23] and lately novel conductor particlesdoped composite electrodes. ...

Hot electron-induced electrogenerated chemiluminescence of Ru(bpy)32+ chelate at a pointed active metal cathode in fully aqueous solutions
  • Citing Article
  • October 2016

Journal of Electroanalytical Chemistry