K N Rustogi's research while affiliated with Colgate-Palmolive and other places

Publications (51)

Article
To investigate in a double-blind clinical study the effectiveness of a dentifrice containing triclosan and a copolymer (Colgate Total Toothpaste) for controlling breath odor 12 hours after brushing the teeth. A panel of four expert judges using a nine-point hedonic scale evaluated breath odor. Following a baseline evaluation of breath odor, prospec...
Article
The objective of this single-use, examiner-blind, two-treatment crossover clinical study was to evaluate the efficacy of a new battery-powered toothbrush (Colgate MicroSonic) relative to that of a currently marketed manual toothbrush (Oral-B Indicator) for the removal of supragingival plaque. This study included the assessment of plaque removal in...
Article
The objective of this six-week, examiner-blind clinical study was to assess the tooth whitening and extrinsic stain prevention efficacy of a new dentifrice delivering 1.0% hydrogen peroxide, 0.243% sodium fluoride, and sodium tripolyphosphate in a high-cleaning silica base (Test Dentifrice) relative to that of a commercially available hexametaphosp...
Article
The objective of this six-week, examiner-blind clinical study was to assess the tooth whitening and extrinsic tooth stain removal efficacy of a new dentifrice delivering 1.0% hydrogen peroxide, 0.243% sodium fluoride, and sodium tripolyphosphate in a high-cleaning silica base (Test Dentifrice), relative to that of commercially available hexametapho...
Article
The objective of this four-week, double-blind clinical study was to assess the tooth whitening efficacy of a new dentifrice delivering 1.0% hydrogen peroxide, 0.243% sodium fluoride, and sodium tripolyphosphate in a high-cleaning silica base (Test Dentifrice), relative to that of a control dentifrice containing 0.243% sodium fluoride in a silica ba...
Article
This single-use, examiner-blind clinical study evaluated the efficacy of a newly introduced battery-powered toothbrush (Colgate Motion Toothbrush) relative to a manual toothbrush (Oral-B CrossAction toothbrush) for the removal of supragingival plaque. This study assessed plaque removal via the comparison of pre- and post-brushing plaque levels. A t...
Article
The objective of this single-use, examiner-blind clinical study, was to evaluate the efficacy of a newly designed Colgate Actibrush (battery-powered toothbrush) relative to the Crest SpinBrush (battery-powered toothbrush) for the removal of supragingival plaque. This study included the assessment of plaque removal via the comparison of pre- and pos...
Article
A double-blind, 3-week, randomized, placebo-controlled, parallel-group clinical trial was conducted to evaluate the tooth-whitening efficacy of a novel nontray, "paint-on" liquid whitening gel containing 18% carbamide peroxide (Colgate Simply White Clear Whitening Gel). Efficacy was based on measured Vita tooth-shade scores collected at baseline an...
Article
Dentifrices traditionally have been formulated as pastes or gels. However, liquid varieties recently have become available The authors conducted a study to determine whether a fluoridated liquid product with added triclosan and a polyvinyl methyl ether/maleic acid, or PVM/MA, copolymer delivery system is efficacious for the control of supragingival...
Article
The objective of this double-blind clinical study, conducted in harmony with American Dental Association guidelines, was to compare a new dentifrice formulation variant of Colgate Total Toothpaste containing a special grade of silica (Colgate Total Plus Whitening Toothpaste) to the commercially available, ADA-Accepted and clinically proven Colgate...
Article
Two independent studies were conducted to evaluate and compare the clinical performance of two commercially available manual toothbrushes (Colgate Total Professional and the Oral-B Cross Action). Study I was a short-term, examiner-blind crossover clinical trial (N = 30) designed to measure the removal of 24-hour plaque build-up. All subjects refrai...
Article
The objective of this 30-day clinical study, conducted in harmony with American Dental Association guidelines, was to evaluate the efficacy of a new battery-powered toothbrush (Colgate Actibrush) relative to a manual toothbrush (Colgate Plus Diamond Head Toothbrush, Full Head, Soft Bristle) in the control of supragingival plaque and gingivitis. A t...
Article
The objective of this clinical program was to compare the efficacy of the Colgate Actibrush battery-powered toothbrush and the Oral-B CrossAction Toothbrush (full head, soft bristle) for the control of supragingival plaque and gingivitis. Two independent clinical studies were conducted: Study 1 (repeated 3 times) was a single-use, examiner-blind cl...
Article
The objective of these four clinical studies was to evaluate the efficacy of the Colgate Actibrush battery-powered toothbrush in comparison with four top-selling manual European toothbrushes (Dr. Best Flex Toothbrush [Germany]; Reach Triple Action Ultra Clean Toothbrush [Germany]; Jordan Multi-Action Toothbrush [Norway]; and Sanogyl Systeme In'Side...
Article
This examiner-blind clinical study evaluated the efficacy of a new battery-powered toothbrush with oscillating head (Colgate Actibrush) on established gingivitis and plaque at 15 days and again at 30 days, as compared to a control manual toothbrush (American Dental Association [ADA]-provided toothbrush, full head, soft bristles). A total of 63 part...
Article
This clinical study compared the effect of Colgate Actibrush, a battery-powered toothbrush, and Colgate Plus Diamond Head, a full-head, soft-bristled manual toothbrush, on established supragingival plaque and gingivitis over a 30-day period. Sixty-two healthy adult men and women were entered in the study. The subjects were stratified into two balan...
Article
The objective of this double-blind clinical study was to investigate the effectiveness of a dentifrice containing triclosan and a copolymer, Colgate Total Toothpaste, for controlling breath odor twelve hours after brushing the teeth compared to a placebo dentifrice which did not contain triclosan or a copolymer. Breath odor was evaluated by a panel...
Article
The objective of this double-blind clinical study was to compare the efficacy for extrinsic tooth stain removal of four commercially available dentifrices: Colgate Tartar Control with Baking Soda & Peroxide Fluoride Toothpaste; Aquafresh Advanced Whitening Toothpaste with Fluoride; Rembrandt Tartar Control Low Abrasion Fluoride Whitening Toothpaste...
Article
The objective of this double-blind clinical study was to compare the extrinsic tooth stain removal efficacy of three commercially available dentifrices: Colgate Platinum Whitening Toothpaste with Fluoride, Aquafresh Advanced Whitening Toothpaste with Fluoride, and Crest Regular Fluoride Toothpaste. Following a baseline examination for extrinsic too...
Article
The objective of this double-blind clinical study was to investigate the effectiveness of a commercially available dentifrice containing triclosan and a copolymer (Colgate Total Toothpaste) for controlling long-term, i.e., seven-hour and overnight breath odor. In particular, a comparison was made between the level of control of breath odor provided...
Article
A three-month, double-blind, parallel clinical study was conducted on a population of Thai adults to evaluate the effect of the twice daily use of a commercially available pre-brush mouthrinse on supragingival calculus formation. The mouthrinse test product contained 0.03% triclosan and 0.13% PVM/MA copolymer with the absence of fluoride. The subje...
Article
A six-month, double-blind parallel clinical study was conducted to evaluate the efficacy on existing plaque and gingivitis of a pre-brush mouthrinse (Colgate Plax, Thailand) containing 0.03% triclosan and 0.13% of a polyvinylmethyl ether/maleic acid (PVM/MA) copolymer in the absence of fluoride, as compared to a matching placebo rinse. A total of 1...
Article
The purpose of this research was to evaluate Colgate original Tartar Control dentifrice (TC) and new Colgate Micro Cleansing Tartar Control (MCTC) dentifrice in a laboratory and clinical study for their ability to remove induced stain. In the laboratory study, polished and etched bovine enamel specimens were stained for 4 days with a coffee, tea, a...
Article
Significant differences in stain removal have been demonstrated in a laboratory study comparing two tartar control dentifrices: Platinum, containing 1.3% soluble pyrophosphate and 1.5% of a copolymer, and Crest Tartar Control, containing 5% soluble pyrophosphate. The purpose of this clinical study was to evaluate the same tartar control dentifrices...
Article
The Colgate Total (formerly Colgate Precision) was evaluated along with the New Improved Crest Complete, Reach Advanced Design and Oral-B Advantage toothbrushes to compare six-week and three-month effects on plaque and gingivitis. One-hundred and ninety-three male and female participants completed a three-month, unsupervised toothbrushing study, br...
Article
A clinical study was performed to evaluate and compare the plaque-removal performance of a recently introduced, computer-designed manual toothbrush with that of two commercially available products; the Oral-B 40 and the Reach Full-Head soft toothbrushes. Seventy-five adult male and female subjects participated, each refraining from toothbrushing fo...
Article
A one-year, double-blind clinical study was conducted on a population of Thai children and teenagers to determine the effect of the twice daily use of an anticalculus dentifrice on supragingival calculus formation and gingival recession, as compared to the use of a placebo dentifrice and the continuation of customary oral hygiene procedures. The su...
Article
A 5-day, double-blind parallel clinical study was conducted to determine the antiplaque efficacy of a pre-brush rinse containing 0.03% triclosan and 0.125% of a copolymer of polyvinyl methyl ether maleic acid as compared to a matching matching placebo pre-brush rinse. A total of 114 subjects were stratified into two balanced groups according to bas...
Article
To improve the assessment of plaque present on teeth, a new index, based on the original Modified Navy Plaque Index, has been developed. The primary modifications to the original Modified Navy Plaque Index were: (1) extending areas F (distal) and D (mesial) into the region just below the interproximal contact point, and (2) extending areas C and A...
Article
Two independent cross-over design studies were performed to compare two toothbrushes for their ability to remove plaque. In Study I, the Colgate Precision toothbrush was compared to the Oral-B 40 toothbrush; in Study II, the Colgate Precision toothbrush was compared to the Reach Full-Head soft toothbrush. A total of 54 and 72 adult male and female...
Article
Two independent studies were conducted to evaluate and compare the clinical performance of three toothbrushes on plaque removal. Both studies were carried out under the same protocol. A total of 73 adult male and female subjects who met the inclusion/exclusion criteria completed Study I and 78 different subjects completed Study II. Subjects were in...
Article
A total of one hundred twenty-one (121) adult male and female subjects completed a 6-month, double-blind clinical study comparing the effect on supragingival plaque formation and gingivitis of a dentifrice containing 0.3% Triclosan and 2.0% of a copolymer of methoxyethylene and maleic acid to a placebo dentifrice. Both the Triclosan/copolymer and p...
Article
The accurate assessment of gingival recession is important because of soft tissue deterioration and/or the state of soft tissue health. While recession of the gingival margin is a common and important symptom of periodontal disease, it also refers to the location of the gingiva and not to its condition. Recession can occur at all tooth surfaces. Th...
Article
A one-year, double-blind clinical study was conducted on a population of male and female adults to determine the effect of the twice daily use of an anticalculus dentifrice on supragingival calculus formation and gingival recession, as compared to the use of a placebo dentifrice. The subjects were initially evaluated for calculus using the Volpe-Ma...
Article
This research evaluated the effect of an anticalculus mouthrinse, containing 3.3% pyrophosphate anion and 1.0% of a copolymer of vinylmethyl ether and maleic acid (Gantrez), on calculus formation, gingivitis, gingival recession, and epithelial attachment in beagle dogs over a one-year period of time, compared to a distilled water rinse. Each was ap...
Article
A survey was performed on a sample of children and teenagers in Thailand. The sample consisted of 260 subjects ages 10-17 years. Assessments of the prevalence and amount of supragingival calculus (Volpe-Manhold) on the facial and lingual surfaces of the six mandibular anterior teeth were recorded. All subjects then received a thorough whole mouth p...
Article
A one-year, double-blind clinical study was conducted on a population of Thai children and teenagers to determine the effect of the twice daily use of an anticalculus dentifrice on supragingival calculus formation and gingival recession, as compared to the use of a placebo dentifrice and the continuation of customary oral hygiene procedures. The su...
Article
A 6-day, double-blind parallel clinical study was conducted to determine the effect on plaque formation of a mouthrinse containing 0.03% triclosan (Irgacare MP) and 0.25% of a copolymer of methoxyethylene and maleic acid (Gantrez), as compared to a flavored/colored water placebo mouthrinse and Plax antiplaque pre-brushing dental rinse. A total of 6...
Article
A 6-day, double-blind parallel clinical study was conducted to determine the effect on plaque formation of a mouthrinse containing 0.03% [corrected] triclosan (Irgacare MP) and 0.25% of a copolymer of methoxyethylene and maleic acid (Gantrez), as compared to a flavored/colored water placebo mouthrinse. A total of 47 subjects were stratified into tw...
Article
A two phase, six month, double blind clinical study was conducted to compare the effect on supragingival calculus deposits of a dentifrice containing 1.30% soluble pyrophosphate (from 2.0% tetrasodium pyrophosphate) with and without the presence of 1.50% of a copolymer of methoxyethylene and maleic acid. In Phase I of the study, male and female adu...
Article
A 6-week, double-blind, clinical study was conducted to determine the effect on plaque formation of a dentifrice containing 0.3% triclosan and 2% of a copolymer of methoxyethylene and maleic acid as compared to a placebo dentifrice. Ninety-one male and female adult subjects with baseline Quigley-Hein Plaque Index scores of 1.5 or greater were enter...
Article
A three-month, double-blind clinical study was conducted to compare the effects of supragingival calculus deposits of a mouthrinse containing soluble pyrophosphate and a copolymer of methoxyethylene and maleic acid, as compared to a mouthrinse containing only soluble pyrophosphate and a placebo mouthrinse. Male and female adult subjects were strati...
Article
Full-text available
An electrostatic complex of 0.1% benzethonium chloride (BTC) plus 0.05% copolymer of methoxyethylene and maleic acid was evaluated in vitro for antibacterial effect. The complex by itself showed as much antibacterial activity as 0.1% BTC. The adsorption of 14C-BTC on saliva-coated hydroxyapatite disks and teeth in vitro was lower from the complex t...
Article
A METHOD was developed and evaluated in a pilot study to determine a relationship between gingival health, crevicular fluid flow and the production of H2S from the crevicular fluid. A moderate degree of correlation was observed between the crevicular fluid volume and the gingival index. A stronger correlation was obtained between the crevicular flu...
Article
Beagle dogs were treated with 0.1 % aqueous solution of benzethonium chloride or with water for 27 weeks and for an additional three weeks to ascertain whether or not the plaque inhibiting effect of BTC was altered because of initial long-term treatment. The results of this study show 0.1 % BTC significantly reduced plaque and gingivitis in beagles...

Citations

... (2) for dentifrices, there were no statistical significant differences among different test groups, although the worst results were found for sanguinarine and baking soda; (3) for mouth rinses, Although different systematic reviews on the efficacy of antiplaque agents have been published, most of them focused only on one single product (Addy, Moran, & Newcombe, 2007;Afennich, Slot, Hossainian, & Weijden, 2011;Davies, Ellwood, & Davies, 2004;Hossainian, Slot, Afennich, & Weijden, 2011;Paraskevas & van der Weijden, 2006) or on the comparison between two products (van Leeuwen, Slot, & Weijden, 2011;Salzer, Slot, Dorfer, & Weijden, 2015). The efficacy of multiple formulations was assessed by Gunsolley (2006), but no attempt was made to compare different products. ...
... 8 One way to improve oral hygiene would be to use a dentifrice targeted at chemical inhibition of calculuspreferably combined with low foaming action. Tartar control dentifrice decreases calculus formation in adults and children, [15][16][17] and newer tartar-control dentifrices show improved efficacy. 18,19 The purpose of this study was to determine if regular use of an anticalculus dentifrice with low-foaming action (Crest Dual Action Whitening toothpaste) 18,19 reduces calculus formation in children with gastrostomy compared to Crest Cavity Protection toothpaste. ...
... An investigation was carried out for the whole mouth and for gingival margin and proximal sites alone. Plaque levels were measured using the Rustogi Modified Navy Dental Plaque Index (RMNPI) (Rustogi et al., 1992), an index widely used in PTB studies that can show differentiation in dental plaque removal in the approximal tooth regions (Biesbrock et al., 2007;Goyal et al., 2009;Klukowska, Grender, Goyal, et al., 2012;Rosema et al., 2016;Sharma et al., 2011). The study also had a safety objective to evaluate the oral tolerance of the toothbrushes. ...
... Thus, the round-ended bristles have been found to be effective in plaque control. The results of the present study are in accordance to Rustogi et al., [12] Sharma et al., [13] and Singh et al. [14] who employed Navy index to quantify the plaque. They compared five toothbrushes having round-ended bristles, multi-level straight bristles with three advanced crisscross bristles, and found that advanced crisscross bristles were superior among them in plaque reduction. ...
... Thus, the round-ended bristles have been found to be effective in plaque control. The results of the present study are in accordance to Rustogi et al., [12] Sharma et al., [13] and Singh et al. [14] who employed Navy index to quantify the plaque. They compared five toothbrushes having round-ended bristles, multi-level straight bristles with three advanced crisscross bristles, and found that advanced crisscross bristles were superior among them in plaque reduction. ...
... [5][6][7][8] Así mismo, hay estudios que muestran que el uso previo al cepillado de triclosán, copolímeros y fluoruro puede dar buenos resultados en el control del biofilm. [9][10][11][12][13][14] De esta manera, el objetivo de nuestra investigación es comparar la reducción del número de superficies con biofilm, que se presenta con el uso de los aceites esenciales previo al cepillado dental, respecto de la que encontramos al usarlos posterior al mismo. ...
... Pyrophosphate interrupts the conversion of amorphous calcium phosphate to hydroxyapatite, which consists of dental calculus [8]. With the use of the pyrophosphate-containing dentifrice, a previous study reported that the formation of calculus was reduced by 40% after a year [9]. In addition to the reduced amount of calculus, it was confirmed by scanning electron microscope imaging that the structure of calculus was less compact when pyrophosphate was applied [10]. ...
... 8 One way to improve oral hygiene would be to use a dentifrice targeted at chemical inhibition of calculuspreferably combined with low foaming action. Tartar control dentifrice decreases calculus formation in adults and children, [15][16][17] and newer tartar-control dentifrices show improved efficacy. 18,19 The purpose of this study was to determine if regular use of an anticalculus dentifrice with low-foaming action (Crest Dual Action Whitening toothpaste) 18,19 reduces calculus formation in children with gastrostomy compared to Crest Cavity Protection toothpaste. ...
... The GI reduction of 0.25 and 0.22 observed in the CHX/triclosan and Triclosan groups, respectively, are in agreement with other trials which assessed the effects of a dentifrice containing triclosan in these clinical parameters [27][28][29]. Moreover, in a metaanalysis performed by Hioe & van der Weijden [23], the authors found an IG reduction of 0.24 and 0.48 in PI, favoring triclosan. ...
... Several factors have been associated with GR (Zucchelli and Mounssif, 2015), but a relatively higher prevalence and severity of GR on the lingual surface of mandibular anteriors (incisors and canines) is ascribed to poor oral hygiene (Loe et al., 1992;Marini et al., 2004). A positive association between the amount of calculus and degree of GR has been observed (van Palenstein Helderman et al., 1998;Rustogi et al., 1991). Tongue piercing, poorly constructed removable partial dentures, full coverage restorations with intracrevicular margins, and orthodontic therapy can be other contributing etiological factors (Campbell et al., 2002;Assis et al., 2017;Kim and Neiva, 2015). ...