Jung Hie Lee's research while affiliated with Kangwon National University Hospital and other places

... Another recent clinical trial demonstrated the efficacy of bright light therapy in improving objective cognitive function in the survivors of hematopoietic stem cell transplants [24]. Blue-enriched light therapy has been found to be beneficial in improving general cognitive function in patients with mild and moderate Alzheimer's disease (AD) [25]. Overall, it seems that light intervention is useful for improving alertness in healthy individuals, but the evidence for its effect on other cognitive functions, such as memory, attention, and executive function, is not adequate. ...

... The medical screening included routine clinical tests on blood and urine, an electrocardiogram, a physical examination, and a medical history to rule out acute or chronic illnesses and medication use. All participants were in good psychological health as determined by the Geriatric Depression Scale, Mattis Dementia Rating Scale, Folstein Mini-Mental State Exam, the Minnesota Multiphasic Personality Inventory-2, and by clinical interview [30], and all were free from clinically significant sleep disorders as determined by all-night clinical polysomnography. None of the participants were under the care of a physician for any chronic medical condition, and none were regularly taking medications. ...

... ight melatonin onset. Typically, good sleepers attempt sleep about 2 h after their DLMO and have short sleep latencies. The insomnia participants attempting sleep at an abnormally early circadian phase had exceptionally longer sleep latencies. They suggested that these insomnia participants were attempting sleep within their wake-maintenance zones.Kim et al. (2020) have also shown a relation between the timing of DLMO and sleep maintenance problems. The earlier the dim light melatonin onset, the more wake time was experienced after initial sleep onset. ...

... While van Veen et al. (2010) reported an attenuated 24 h amplitude of the rest-activity pattern and lower interdaily stability of adults with insomnia comorbid with ADHD, no differences in inter-or intradaily rhythm variables were found in children with ADHD and insomnia (van der Heijden et al., 2005). The few other studies published on diurnal rhythm variables in insomnia also failed to find differences between patients and controls (Kim, Lim, Kwon, & Lee, 2020;Natale et al., 2009), with the actual numbers of null results possibly being much larger due to the file drawer problem (Rosenthal, 1979). ...

... Therefore, many people have started engaging in positive activities, such as physical exercise and maintaining a healthy diet, which factors can relieve the symptoms of their psychological distress and sleep disorders [37]. Exercise is useful for improving the sleep quality and quality of life of insomniacs [38]. Individuals can also engage in diversionary activities to distract from observing COVID-19-related news to avoid potentially incorrect information. ...

... Sleep timing and central circadian characteristics of older and younger adults. Sleep/wake timing was earlier in older participants from Scheuermaier et al. 22 , compared to younger participants from Rahman et al. 23 , who were studied in equivalent protocols ( Supplementary Fig. 1). Endogenous circadian phase of the melatonin rhythm was earlier in the older group than in the younger group, but the difference in relative alignment between sleep and circadian phase of the melatonin rhythm was not different between the age groups. ...

... Circadian measures unrelated to the above approach are labelled non-parametric and provide information on rhythm fragmentation (IV), day-to-day similarity of activity patterns (IS), relative amplitude of restactivity rhythm (RA), least active hours (L5) and most active hours (M10) of the day. used actigraphy in conjunction with sleep diaries to analyse naps in patients with ID and HC [28]. ID patients showed higher nap frequency than HC, and additionally, the napping frequency was associated with poorer subjective sleep quality (assessed through the Pittsburgh Sleep Quality Index, PSQI) [28]. ...

... In this study, the KESS scores of the NC were significantly higher than those of insomnia group without exercise (Table 3). Although it may be expected that daytime sleepiness will occur to compensate for sleep deprivation in insomnia patients, it has been reported that daytime sleepiness may decrease due to the disrupted sleep homeostasis [39]. In this study, the degree of hyper-arousal indicated by the HAS was observed to be higher in the insomnia group than the NC group, although the difference was not statistically significant. ...

... The delay in bed time in teens is caused by a combination of both biological (i.e., puberty-associated delay in the timing of the circadian clock) and social factors (e.g., increased socialization, education requirements, entertainment options) [3]. For individuals who are evening-type, the delay may be worse and lead to even shorter sleep durations and greater daytime sleepiness [4,5]. ...

... It was suggested that carriers of the morningness allele (C) had an MEQ score on average 2.8 higher than T/T homozygotes (Katzenberg et al., 1998). However, with one exception (Mishima, Tozawa, Satoh, Saitoh, & Mishima, 2005), no other groups have reported being able to replicate this finding (Barclay et al., 2011;Chang, Buch, Bradstreet, Klements, & Duffy, 2011;Choub et al., 2011;Kim, Lee, Lee, Hwang, & Suh, 2016;Pedrazzoli et al., 2007;Robilliard et al., 2002). There is also a single report of association between an intronic polymorphism (rs922270) in the ARNTL2 gene, which encloses BMAL2, and MEQ score (Parsons et al., 2014). ...