Joshua Hill's research while affiliated with Illinois State University and other places

Publications (3)

Article
Full-text available
Organisms are commonly infected by a diverse array of pathogens and mount functionally distinct responses to each of these varied immune challenges. Host immune responses are characterized by the induction of gene expression, however, the extent to which expression changes are shared among responses to distinct pathogens is largely unknown. To exam...
Article
Full-text available
Significance The ability of immune cells to distinguish self tissue from nonself pathogens is a key characteristic of immunity, allowing responses to be targeted against invading pathogens while protecting against self-directed immune damage. The recognition of nonself by innate immune cells has been extensively characterized, but the mechanisms th...
Preprint
Full-text available
Background: Organisms are commonly infected by a diverse array of pathogen types including bacteria, fungi, viruses, and parasites, and mount functionally distinct responses to each of these varied immune challenges. Host immune responses are characterized by the induction of gene expression in response to infection. However, the extent to which ex...

Citations

... Several reasons might account for this. On the one hand, it is possible that there are significant differences in responses to infections with different pathogens, an aspect that is certainly important (38,39). On the other hand, these differences may also represent secondary effects that could be explained by different degrees of infection events and responses caused by them (40, 41). ...
... The implication of glycans in important cellular mechanisms in non-EV-related studies, such as cell adhesion [18,19], self-and non-self-recognition [20,21], molecular trafficking and receptor activation, has turned glycans into a new focus of molecules in which to find the possible mechanisms of EV function and targeting. In this context, a few studies (reviewed in [22,23]) have already reported EV glycan profiling analysis or specific receptor-ligand interactions for EV uptake in a glycan-dependent manner. ...