Joseph Kaleeny’s research while affiliated with The Ohio State University and other places

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Publications (6)


Fig. 3. Flowchart of studies included in the practical review.
Fig. 4. Funnel plot of meta-analysis.
Fig. 5. Galbraith plot of meta-analysis.
Fig. 6. Forest plot of subgroup analysis among various types of treatment modalities and different lesion locations.
Fig. 7. clinical presentation of a PG on the second digit of the hand. Photograph attribution: clS Digital Arts, iD: 182431496.

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Pyogenic Granuloma Diagnosis and Management: A Practical Review
  • Literature Review
  • Full-text available

September 2024

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370 Reads

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4 Citations

Joseph D. Kaleeny

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Jeffrey E. Janis

Background Pyogenic granuloma (PG), or lobular capillary hemangioma, poses a clinical challenge with its uncertain etiology and treatment options. Although the clinical features and prevalence of PGs are well established, definitive evidence-based treatments remain elusive. This practical review aims to illuminate the complexities of PG management by analyzing surgical interventions based on literature analysis. Methods A PubMed/Medline search of “pyogenic granuloma” and “surgery” yielded 1171 studies. Inclusion criteria targeted intervention-associated PG complications over 5% and treatment modalities, excluding nonclinical studies and topics unrelated to plastic and reconstructive surgery. Screening involved Oxford level of evidence, patient data extraction, complications, intervention types, success rates, sessions, follow-ups, and treatments. Results Thirty-one studies met inclusion criteria. Most studies were retrospective (67.7%). Ten studies satisfied intervention-linked eruptions, primarily oculoplastic, whereas 21 investigated both surgical and nonsurgical treatment modalities. Across interventions, 3579 patients (age: 34.2–85.7 years) were involved. Postsurgical PG complications averaged 15.1% and were treated predominantly with surgical excision, achieving nearly complete resolution. Surgical and nonsurgical treatment studies included 1233 patients (age: 3–46.5 years), demonstrating a 68.2% average resolution after a single session, with surgical excision exhibiting the highest success rate (96.2%) and minimal complications. Conclusions This practical review highlights the complexities of managing PG, emphasizing a spectrum of effective treatments and potential postoperative complications. Ophthalmologic procedures showed PG incidences of 9%–24.4%. Surgical excision proved highly effective, surpassing methods like lasers and injectables that exhibited varied success rates requiring multiple treatment sessions. Challenges included study diversity and varying evidence levels, warranting further comparative research for PG management strategies.

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Distribution of different types of study and their level of evidence across JAMA
Level of evidence in high impact surgical literature: the way forward

August 2024

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86 Reads

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1 Citation

Updates in Surgery

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Joseph Kaleeny

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[...]

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Evidence-based medicine stipulates that clinical decision-making should revolve around scientific evidence. The goal of the present study is to evaluate the methodological quality of surgical research recently published in JAMA Surgery, International Journal of Surgery, and British Journal of Surgery, the three surgical journals with the highest impact factor. An electronic search of the PUBMED database was performed to retrieve all articles published in the JAMA Surgery, International Journal of Surgery, and British Journal of Surgery in the year 2022. Three authors independently reviewed all retrieved articles and methodological designs of the publications were analyzed and rated using a modification of the Oxford Centre for Evidence-Based Medicine Levels of Evidence (Oxford Levels of Evidence scale). The initial search identified 1236 articles of which 809 were excluded after title and abstract screening. The remaining 427 underwent full text/methods read, of which 164 did not meet the inclusion/exclusion criteria. A total of 273 studies were included in the analysis. The average level of evidence was 2.5 ± 0.8 across all studies assessed. The majority of study designs were comprised of retrospective cohorts ( n = 119), prospective cohorts ( n = 47), systematic reviews of non RCTs ( n = 39), and RCTs ( n = 37). There was no significant difference in the average level of evidence between the top three journals ( p = 0.50). Most clinical studies in the highest impact factor surgical journals are of level III evidence, consistent with earlier literature. However, our analysis demonstrates a relatively higher percentage of LOE I and II compared to what was previously published in the literature.


Results of Meta-Analysis. BDD prevalence in individuals of studies with 95% confi- dence intervals.
Cont.
Results of Subgroup Meta-analysis.
Body Dysmorphic Disorder in Aesthetic and Reconstructive Plastic Surgery—A Systematic Review and Meta-Analysis

July 2024

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132 Reads

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6 Citations

(1) Background: Body dysmorphic disorder (BDD) presents significant challenges in aesthetic and reconstructive plastic surgery, impacting patient outcomes and well-being. Understanding its prevalence and associated factors is crucial for effective patient care. (2) Methods: A systematic review of national and international databases on body dysmorphic disorder, plastic surgery, cosmetic surgery, reconstructive surgery, and prevalence yielded 999 studies between 1878 and April 2024. Inclusion criteria focused on studies reporting prevalence while excluding those with small sample sizes (<20 participants), unclear diagnostic criteria for BDD, and non-English accessibility. (3) Results: A meta-analysis using a random effects model was conducted on 65 studies involving 17,107 patients to estimate the prevalence of BDD. The overall estimated prevalence of BDD was 18.6%; 10,776 (62.9%) were females, with a mean age of 35.5 ± 11.7 years. Subgroup meta-analysis found significant variability in effect sizes across countries and types of specialty, of which Brazil showed the highest proportion and dermatology exhibited the smallest. Meta-regression analysis found no significant relationship between the year of publication and prevalence rates. (4) Conclusions: Our findings update the current literature on BDD prevalence in aesthetic and reconstructive plastic surgery. We emphasize the importance of proactive screening and multidisciplinary care approaches to address the complex challenges posed by patients with BDD. Further research is needed to explore evolving trends in BDD prevalence and factors influencing its expression across different cultural contexts.


Blepharoplasty Online: Critical Analysis of Content and Patient Comprehensibility

May 2024

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36 Reads

Aesthetic Plastic Surgery

Introduction Patients frequently turn to online information for decision-making factors about aesthetic procedures. The quality of online medical content is an essential supplement to clinical education. These resources assist patients in understanding the risks, benefits, and appropriateness of their desired procedure. This study examines the breadth and readability of online blepharoplasty information, elucidating its educational utility. Methods A depersonalized Google search was conducted using the Startpage Search Engine, investigating key phrases, “blepharoplasty decision making factors”, “eye lift decision making factors”, and “eyelid lift decision making factors”. The first three pages of results for each search term, totaling 90 links were screened. Data were extracted for various decision-making factors, subspecialty, gender, and readability. Results Twenty-six websites met inclusion for analysis. Thirteen websites were plastic surgery based, five otolaryngology (ENT), five ophthalmology/oculoplastic, one oral-maxillofacial (OMFS), and two mixed-based practices. Most blepharoplasty webpages identified were that of private practice and male surgeons. Half were subspecialties other than plastic surgery. Thirteen common decision-making factors were identified. The most common factors addressed across all texts were recovery followed by cosmetic and functional goals. The least discussed were genetic factors. Average Readability exceeded the 12th grade. There were no significant differences in readability means among subspecialties. Conclusion This study examines the online blepharoplasty sphere among US-based practices providing clinical education to patients. No appreciable differences among gender, subspecialty, and readability on decision-making factors were found, highlighting a consistency among surgeons. Most websites fell short of readability standards, however, emphasizing a need for clearer information to patients. No Level Assigned This journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Correspondence: Morphological features of the greater occipital nerve and its possible importance for interventional procedures

December 2023

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13 Reads

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1 Citation

Journal of Anatomy

This response applauds Saglam et al.'s (2023) recent study on the greater occipital nerve's anatomy while urging readers to consider earlier pivotal studies overlooked. It emphasizes how prior research has significantly shaped headache treatments and provides valuable insights for future practices and discussions.


The current use of tissue expanders in breast reconstruction: device design, features, and technical considerations

November 2023

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29 Reads

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3 Citations

Introduction: The use of tissue expanders (TE) in post-mastectomy breast reconstruction is a widely accepted practice, especially in patients desiring implant-based breast reconstruction. It has become the standard of care to perform a two-staged breast reconstruction using tissue expanders for the past 50 years due to its reliability, safety, cost-effectiveness, and versatility. Due to its popularity, there are numerous types and features of breast tissue expanders and various surgical approaches available for plastic surgeons. Areas covered: In this article, we will review the role of tissue expanders in breast reconstruction, the types and features of breast tissue expanders, and technical considerations. Expert opinion: The use of tissue expanders in breast reconstruction offers significant advantages of preserving the breast skin envelope and reestablishing the breast mound. With evolving approaches to breast reconstruction, tissue expander design, and application underwent several refinements and modifications. Due to these advances, studies on its long-term efficacy and safety profile typically fall behind and more studies with higher levels of evidence are needed to better evaluate the efficacy and safety profile of tissue expanders. With increased understanding, reconstructive surgeons can minimize complications and maximize reconstructive, aesthetic outcomes with high patient satisfaction.

Citations (5)


... An occasional intra-oral finding in the third trimester is the Pyogenic granuloma (7). This is a benign enlargement of the gingival tissue that is prone to bleeding (7). Oral hygiene practices tend to play a major role in the development of periodontal problems in pregnancy (8). ...

Reference:

INSIGHTS-JOURNAL OF HEALTH AND REHABILITATION ASSOCIATION OF ORAL HYGIENE PRACTICES AND PERIODONTAL HEALTH IN FEMALES WITH RESPECT TO THE TRIMESTER OF PREGNANCY
Pyogenic Granuloma Diagnosis and Management: A Practical Review

... The article by ElHawary et al. [3] in this issue of Updates in Surgery is timely. The authors reviewed all clinical studies published in three high impact factor surgical journals in the year 2022 to determine the level of evidence using a modification of the Oxford Centre for Evidence-based Medicine Levels of Evidence [4]. ...

Level of evidence in high impact surgical literature: the way forward

Updates in Surgery

... 17,18 Additionally, some patients seeking cosmetic surgery may have underlying psychological issues, such as, dysmorphophobia, narcissism, or, particularly, body dysmorphic disorder, which is especially significant due to its high prevalence in plastic surgery patients, estimated at approximately 18.6%. [19][20][21] These conditions often result in unrealistic or unachievable surgical goals, and such patients are unlikely to be satisfied regardless of the surgical outcome. 22 Therefore, selecting the right patients is crucial for postoperative satisfaction. ...

Body Dysmorphic Disorder in Aesthetic and Reconstructive Plastic Surgery—A Systematic Review and Meta-Analysis

... Blockade of the greater occipital nerve by infiltration with local anesthetics and/or steroids (GONB) has been successfully used to treat various forms of headache, including PDPH [31]. Several procedures have been described and there is ongoing research on how anatomic features may impact GONB efficacy [32][33][34]. In a recent randomized, double-blinded study, reduction in pain severity was compared in patients suffering from PDPH receiving either distal or www.co-anesthesiology.com ...

Correspondence: Morphological features of the greater occipital nerve and its possible importance for interventional procedures
  • Citing Article
  • December 2023

Journal of Anatomy

... Tissue expanders (TEs) are temporary devices utilized in breast reconstruction to establish a mound after a mastectomy, and are placed in vivo and exert forces on the chest [75,76]. Prior to exploring the device forces exerted internally, a brief description on its placement should be discussed [75,76]. ...

The current use of tissue expanders in breast reconstruction: device design, features, and technical considerations
  • Citing Article
  • November 2023