Jorge L. Armony's research while affiliated with McGill University and other places

Publications (124)

Article
A growing number of functional neuroimaging studies have identified regions within the temporal lobe, particularly along the planum polare and planum temporale, that respond more strongly to music than other types of acoustic stimuli, including voice. This “music preferred” regions have been reported using a variety of stimulus sets, paradigms and...
Article
Recognizing individuals through their voice requires listeners to form an invariant representation of the speaker’s identity, immune to episodic changes that may occur between encounters. We conducted two experiments to investigate to what extent within-speaker stimulus variability influences different behavioral indices of implicit and explicit id...
Article
Recent evidence suggests that gains in performance observed while humans learn a novel motor sequence occur during the quiet rest periods interleaved with practice (micro-offline gains, MOGs). This phenomenon is reminiscent of memory replay observed in the hippocampus during spatial learning in rodents. Whether the hippocampus is also involved in t...
Article
Full-text available
Background: Fractional anisotropy (FA) and mean diffusivity (MD) are frequently used to evaluate longitudinal changes in white matter (WM) microstructure. Recently, there has been a growing interest in identifying experience-dependent plasticity in gray matter using MD. Improving registration has thus become a major goal to enhance the detection o...
Preprint
Neural overlap in processing music and speech, as measured by the co-activation of brain regions in neuroimaging studies, may suggest that parts of the neural circuitries established for language may have been recycled during evolution for musicality, or vice versa that musicality served as a springboard for language emergence. Such a perspective h...
Article
Full-text available
Most emotional stimuli, including facial expressions, are judged not only by their intrinsic characteristics, but also by the context in which they appear. Gaze direction, for example, modifies the salience of explicitly presented facial displays. Yet, it is unknown whether this effect persists when facial displays are no longer task-relevant. Here...
Preprint
Full-text available
Background Fractional anisotropy ( FA ) and mean diffusivity ( MD ) are frequently used to evaluate longitudinal changes in white matter microstructure. Recently, there has been a growing interest in identifying experience-dependent plasticity in gray matter using MD . Improving registration has thus become a major goal to enhance the detection of...
Article
Full-text available
When entering a subway car affording multiple targets for action, how do we decide, very quickly, where to sit, particularly when in the presence of a potential danger? It is unclear, from existing motor and emotion theories, whether our attention would be allocated toward the seat on which we intend to sit on or whether it would be oriented toward...
Article
The emotional expression of fear can be processed through a number of modalities, and of varying forms, however, much of the functional imaging literature has centered on investigating fear as expressed through faces. Findings point to an active involvement of the amygdala, and remain fairly consistent in other studies of unimodal fear perception;...
Article
Full-text available
Emotional situations are typically better remembered than neutral situations, but the psychological conditions and brain mechanisms underlying this effect remain debated. Stimulus valence and affective arousal have been suggested to explain the major role of emotional stimuli in memory facilitation. However, neither valence nor arousal are sufficie...
Conference Paper
We investigated how emotional sounds are processed by musicians and non-musicians. Expertise through musical training can shape the way emotional music is processed. However, emotional sounds can arise from other sound sources, too, such as vocal expressions like laughter or cries. Musical expertise can also influence the way these emotional sounds...
Article
The ubiquity of music across cultures as a means of emotional expression, and its proposed evolutionary relation to speech, motivated researchers to attempt a characterization of its neural representation. Several neuroimaging studies have reported that specific regions in the anterior temporal lobe respond more strongly to music than to other audi...
Article
Full-text available
There has been a distinct shift in neuroimaging from localization of function into a more network based approach focused on connectivity. While fMRI has proven very fruitful for this, the hemodynamic signal is inherently slow which limits the temporal resolution of fMRI-only connectivity measures. The brain, however, works on a time scale of millis...
Article
Functional near-infrared spectroscopy (fNIRS) permits measurements of changes in the concentration of oxygenated and deoxygenated hemoglobin, typically with a higher sampling rate than with other imaging methods based on the hemodynamic response. We examined the potential of the fNIRS technique to estimate variations in the latency of hemodynamic r...
Article
Full-text available
Daily life events confront us with new situations demanding responses to usual and unusual rules. Diazepam (DZ), a clinically important drug, facilitates the inhibitory activity of the GABAergic system. Prefrontal cortex, rich in DZ receptors, coordinates necessary resources to direct actions according to rules. The balance between excitatory and i...
Article
Full-text available
There is growing interest in characterizing the neural basis of music perception and, in particular, assessing how similar, or not, it is to that of speech. To further explore this question, we employed an EEG adaptation paradigm in which we compared responses to short sounds belonging to the same category, either speech (pseudo-sentences) or music...
Article
Full-text available
The amygdaloid complex plays a crucial role in processing emotional signals and in the formation of emotional memories. Neuroimaging studies have shown human amygdala activation during rapid eye movement sleep (REM). Stereotactically implanted electrodes for presurgical evaluation in epileptic patients provide a unique opportunity to directly recor...
Article
Bipolar disorder type I (BD-I) is associated with emotion dysregulation. However, experimentally controlled studies of emotion regulation (ER), particularly those examining the brain correlates of the putative deficits, are scarce and their results inconsistent. Nineteen euthymic BD-I patients and 17 healthy controls (HC) underwent functional magne...
Article
Full-text available
Neural overlap in processing music and speech, as measured by the co-activation of brain regions in neuroimaging studies, may suggest that parts of the neural circuitries established for language may have been recycled during evolution for musicality, or vice versa that musicality served as a springboard for language emergence. Such a perspective h...
Article
Full-text available
Previous fMRI studies have suggested that different cerebral regions preferentially process human voice and music. Yet, little is known on the temporal course of the brain processes that decode the category of sounds and how the expertise in one sound category can impact these processes. To address this question, we recorded the electroencephalogra...
Article
Full-text available
Intrinsic emotional expressions such as those communicated by faces and vocalizations have been shown to engage specific brain regions, such as the amygdala. Although music constitutes another powerful means to express emotions, the neural substrates involved in its processing remain poorly understood. In particular, it is unknown whether brain reg...
Article
Full-text available
Temporal Lobe Epilepsy (TLE) is associated with memory and emotional impairments. However, the majority of previous studies examined patients after the affected structures (hippocampus and amygdala) were surgically removed, so it remains unclear to what extent these deficits are associated with the illness itself or are a consequence of the surgery...
Article
Full-text available
Music is a powerful tool for communicating emotions which can elicit memories through associative mechanisms. However, it is currently unknown whether emotion can modulate memory for music without reference to a context or personal event. We conducted three experiments to investigate the effect of basic emotions (fear, happiness, and sadness) on re...
Article
Full-text available
During episodic memory encoding, elaborative encoding strategies have been related to greater performance on later memory tests. However, many clinical populations display a deficit in self-initiating encoding strategies. We designed an fMRI study to examine the neural correlates of self-initiating elaborative encoding. Twenty-three healthy partici...
Article
It has been proposed that angry people exhibit optimistic risk estimates about future events and, consequently, are biased towards making risk-seeking choices. The goal of this study was to directly test the hypothesised effect of trait anger on optimism and risk-taking behaviour. One hundred healthy volunteers completed questionnaires about person...
Article
Full-text available
Converging evidence from animal and human studies suggest that rapid eye movement (REM) sleep modulates emotional processing. The aim of the present study was to explore the effects of selective REM sleep deprivation (REM-D) on emotional responses to threatening visual stimuli and their brain correlates using functional magnetic resonance imaging (...
Article
BACKGROUND: Decreased cortical thickness in frontal and temporal regions has been observed in individuals suffering from post-traumatic stress disorder (PTSD), compared to healthy controls and trauma-exposed participants without PTSD. In addition, individual differences, both functional and structural, in the anterior cingulate cortex (ACC) have be...
Article
Full-text available
The FKBP5 gene, a glucocorticoid receptor (GR)-regulating co-chaperone of stress proteins, is of special interest because of its role in hypothalamic-pituitary-adrenal (HPA)-axis regulation. However, studies finding a genetic relationship between posttraumatic stress disorder (PTSD) and the FKBP5 gene have failed to distinguish between the developm...
Article
A new method for detecting activations in random fields, which may be useful for addressing the issue of multiple comparisons in neuroimaging, is presented. This method is based on some constructs of mathematical morphology - specifically, morphological erosions and dilations - that enable the detection of active regions in random fields possessing...
Article
Substantial advances in our understanding of the neural bases of emotional processing have been made over the past decades. Overall, studies in humans and other animals highlight the key role of the amygdala in the detection and evaluation of stimuli with affective value. Nonetheless, contradictory findings have been reported, especially in terms o...
Article
This article describes what is currently known about the neural structures and mechanisms associated with the processing of emotional auditory information for stimuli with intrinsic or learned affective value. It focuses on the amygdala, as this structure has been consistently shown to be a crucial component of the emotional brain, across several s...
Article
fMRI is a very important tool both in the field of Clinical Neuropsychology and Cognitive Neurocience. In the clinical domain, it is mostly used to locate functional regions such as those associated with motor or language processes, although new applications are being developed. Its use in research has permitted the confirmation, extension and reje...
Data
Regions significantly more activated for the sexual arousal condition than for the amusement and disgust conditions. (XLSX)
Data
Regions more activated for the amusement than for the disgust and sexual arousal conditions. (XLSX)
Article
Full-text available
While the limbic system theory continues to be part of common scientific parlance, its validity has been questioned on multiple grounds. Nonetheless, the issue of whether or not there exists a set of brain areas preferentially dedicated to emotional processing remains central within affective neuroscience. Recently, a widespread neural reference sp...
Data
Voxel peak coordinates for the ‘disgust-neutral’ contrast. (XLSX)
Data
Regions more activated for the disgust condition than for the amusement and sexual arousal conditions. (XLSX)
Data
Voxel peak coordinates for the ‘amusement-neutral’ contrast. (XLSX)
Data
Voxel peak coordinates for the conjunction null analysis of the ‘amusement-neutral’, ‘disgust-neutral’, and ‘sexual arousal-neutral’ contrasts. (XLSX)
Data
Voxel peak coordinates for the ‘sexual arousal-neutral’ contrast. (XLSX)
Article
A new method for detecting activations in random fields, which may be useful for addressing the issue of multiple comparisons in neuroimaging, is presented. This method is based on some constructs of mathematical morphology - specifically, morphological erosions and dilations - that enable the detection of active regions in random fields possessing...
Article
Diazepam (DZ), a clinically important drug, reduces alertness and can interfere with complex cognitive processes. The effect of DZ on the behavioural and neural correlates of rule-guided response selection has not been directly investigated. We studied DZ effects, compared to placebo (PL), on performance and brain responses, using fMRI, during rule...
Article
Full-text available
Parkinson's disease is a movement disorder whose principal symptoms are tremor, rigidity, bradykinesia and postural instability. Initially, drugs like L: -dopa or dopaminergic agonists are able to control these symptoms, but with the progress of the disease these drugs become less effective. Previous studies have reported that repetitive transcrani...
Article
Full-text available
There is a general consensus in the literature that schizophrenia causes difficulties with facial emotion perception and discrimination. Functional brain imaging studies have observed reduced limbic activity during facial emotion perception but few studies have examined the relation to flat affect severity. A total of 26 people with schizophrenia a...
Article
Anhedonia is a negative symptom of schizophrenia that has a detrimental impact on functioning and quality of life. Anhedonia also represents a vulnerability marker for schizophrenia when measured in non-clinical individuals. The investigation of the neural correlates of anhedonia in schizophrenia and non-clinical individuals could provide key insig...
Article
Full-text available
The functioning of the brain is fascinating. It fascinates for the obvious reason that the brain is the commander of all our actions, thoughts, and motivations. By studying its functioning, we hope to obtain crucial information about the biological basis of human cognition and emotion. Neuropsychology is the discipline concerned with these question...
Article
Full-text available
Word reading involves several steps, from the visual perception of each of its constitutent elements to its recognition as an entity with a specific meaning. Various brain structures participate in these processes, depending of the linguistic and cognitive characteristics of the stimulus. Our objective was to characterize brain activity through the...
Article
Full-text available
There is an interest in investigating the relation between emotional memory impairments in schizophrenia and specific symptom dimensions. We explored potential links between emotional memory and social anhedonia severity in patients with schizophrenia and in healthy individuals. Twenty-nine patients with schizophrenia and 27 matched healthy individ...
Article
Full-text available
We recently showed that, in healthy individuals, emotional expression influences memory for faces both in terms of accuracy and, critically, in memory response bias (tendency to classify stimuli as previously seen or not, regardless of whether this was the case). Although schizophrenia has been shown to be associated with deficit in episodic memory...
Article
We examined how individual differences in trait anxiety (TA) influence the neural responses associated with the acquisition and extinction of anticipatory anxiety elicited through a context conditioning paradigm, with particular focus on the amygdala and the subgenual anterior cingulate cortex (sgACC). During two sessions of echo-planar functional...
Article
Previous studies have shown memory deficits in Post-Traumatic Stress Disorder (PTSD) patients, as well as abnormal patterns of brain activity, especially when retrieving trauma-related information. This study extended previous findings by investigating the neural correlates of successful memory encoding of trauma-unrelated stimuli and their relatio...
Article
Full-text available
It is presently unknown whether our response to affective vocalizations is specific to those generated by humans or more universal, triggered by emotionally matched vocalizations generated by other species. Here, we used functional magnetic resonance imaging in normal participants to measure cerebral activity during auditory stimulation with affect...
Article
Trait anxiety and sex have been shown to separately account for some of the observed individual differences in amygdala responses to emotional stimuli, but the combined effect of both factors remains unknown. In this fMRI study, participants varying in trait anxiety scores viewed a series of superimposed face/scene composite images (containing fear...
Article
Functional neuroimaging studies have provided strong support for a critical role of the amygdala in emotional processing. However, several controversies remain in terms of whether different factors-such as sex, valence and stimulus type-have an effect on the magnitude and lateralization of amygdala responses. To address these issues, we conducted a...
Article
Most studies of the influence of emotion on memory performance have focused on accuracy. However, there is evidence that emotion can influence other aspects of memory, in particular response bias (overall tendency to classify items as new or old regardless of the accuracy of the response). Here we investigated the behavioral and neural-related modu...
Article
The amygdala is known to be critical for the enhancement of memory for emotional, especially negative, material. Importantly, some researchers have suggested a sex-specific hemispheric lateralization in this process. In the case of facial expressions, another important factor that could influence memory success is the sex of the face, which could i...
Article
Whereas there is ample evidence for a role of the amygdala in the processing of visual emotional stimuli, particularly those with negative value, discrepant results have been reported regarding amygdala responses to emotional auditory stimuli. The present study used event-related functional magnetic resonance imaging to investigate cerebral activit...
Article
Nella storia dell’umanità, la cognizione e l’emozione sono state considerate due processi mentali distinti e di solito contrapposti. Tracce di questa presunta dicotomia esistono già nella Bibbia, dove leggiamo che “una mente tranquilla vitalizza la carne, ma la passione fa imputridire le ossa” (Proverbi, 14:30). Ma è con i filosofi greci che la cog...