John Hartleb’s scientific contributions

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Publications (1)


Figure. Tick collection sites associated with 2 cases of Heartland virus infection in humans, Kankakee and Williamson Counties, Illinois, USA, 2019. Locations of the counties are indicated by red dots on the Illinois map.
Heartland Virus in Humans and Ticks, Illinois, USA, 2018–2019
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July 2020

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171 Reads

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24 Citations

Emerging Infectious Diseases

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Kristen L. Burkhalter

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April Holmes

In 2018, Heartland disease virus infected 2 persons in Illinois, USA. In 2019, ticks were collected at potential tick bite exposure locations and tested for Heartland and Bourbon viruses. A Heartland virus–positive pool of adult male Amblyomma americanum ticks was found at 2 locations, 439 km apart, suggesting widespread distribution in Illinois.

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Citations (1)


... Amblyomma americanum is a multi-host tick with an ever-expanding distribution that strongly overlaps the geographical presentation of human cases of HRTV, and surveillance studies have identified HRTV-infected ticks in areas proximal to known human cases and across the range of A. americanum occurrence. Virus or viral nucleic acids have been recovered from both nymph and adult stages of A. americanum [18,[44][45][46][47][48][49], though to date, the virus has not been recovered from tick larvae collected in the field. Experimental studies have found larvae to be susceptible, however, with both transovarial and transstadial viral transmission reported [50]. ...

Reference:

Heartland Virus: An Evolving Story of an Emerging Zoonotic and Vector-Borne Disease
Heartland Virus in Humans and Ticks, Illinois, USA, 2018–2019

Emerging Infectious Diseases