Jing Yang's research while affiliated with Southwest Forestry University and other places

Publications (20)

Article
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Edible Macadamia is one of the most important commercial nut trees cultivated in many countries, but its large tree size and long juvenile period pose barriers to commercial cultivation. The short domestication period and well-annotated genome of Macadamia integrifolia create great opportunities to breed commercial varieties with superior traits. R...
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Introduction Aplastic anemia (AA) is a bone marrow hematopoietic failure syndrome mediated by immune cells. The mechanism of this immune disorder is not well understood and therapeutic strategies still need to be improved. Methods Studies have found that abnormalities in metabolisms promote the survival of AA cells. In recent years, an increasing...
Article
Inhalation of xenon gas improves acute kidney injury (AKI). However, xenon can only be delivered through inhalation, which causes non-specific distribution and low bioavailability of xenon, thus limiting its clinical application. In this study, xenon is loaded into platelet membrane-mimicking hybrid microbubbles (Xe-Pla-MBs). In ischemia-reperfusio...
Article
Background Postoperative sepsis is one of the main causes of mortality after liver transplantation (LT). Our study aimed to develop and validate a predictive model for postoperative sepsis within 7 d in LT recipients using machine learning (ML) technology. Methods Data of 786 patients received LT from January 2015 to January 2020 was retrospective...
Article
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Background: Tyrosyl phosphorylation is carried out by a group of enzymes known as non-receptor protein tyrosine phosphatases (PTPNs). In the current investigation, it is hoped to shed light on the relationships between the expression patterns of PTPN family members and the prognosis of acute myeloid leukemia (AML). Methods: PTPN expression was exam...
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Incidence rates of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) are lower but more aggressive in children than in adults due to different biological and host factors. After the clinical application of tyrosine kinase inhibitor (TKI) blocking BCR/ABL kinase activity, the prognosis of ch...
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Ischemia/reperfusion (IR) injury, a main reason of mortality and morbidity worldwide, occurs in many organs and tissues. As a result of IR injury, senescent cells can accumulate in multiple organs. Increasing evidence shows that cellular senescence is the underlying mechanism that transforms an acute organ injury into a chronic one. Several recent...
Article
Chlorpyrifos, a broadly utilized insecticide, inhibits many cellular and physiological processes in plants. Here, the phyto-toxicity of chlorpyrifos on cucumber plants, as well as the dissipation kinetics of chlorpyrifos in leaves, were investigated. Those results showed that chlorpyrifos accumulated primarily in the leaves under normal agrochemica...
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Rationale: Peripheral nerve block is a traditional perioperative analgesic method for its precise pain control and low systemic toxicity. However, a single low dose of local anesthetic merely provides a few hours of analgesia, and high dose results in irreversible toxicity, whereas continuous infusion of anesthetics is expensive and complicated. Th...
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Background Caveolae are plasma membrane subdomains of many mammalian cells that play critical roles in cellular processes, including endocytosis, signal transduction and tumorigenesis. Cavin proteins are essential for caveola formation, structure and function and are reported to be involved in various human diseases, but little is known about their...
Article
The morbidity and mortality of sepsis‐induced acute kidney injury (SAKI) remain high. Early detection using molecular ultrasound imaging may reduce mortality and improve the prognosis. Inspired by the intrinsic relationship between platelets and SAKI, platelet membrane‐coated hybrid microbubbles (Pla‐MBs) are designed for early recognition of SAKI....
Article
Glutamine synthetase (GS) plays an important role in nitrogen (N) metabolism in cucumber. In this study, we cloned and sequenced the CsGS1 gene, and analyzed the expression patterns and subcellular localization of the GS1 protein in response to different N conditions in order to determine its role in low-nitrogen (LN) tolerance. CsGS1 was abundantl...
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Rationale: Early diagnosis of hepatic ischemia-reperfusion injury (HIRI), the major cause of early allograft dysfunction or primary non-function, is critical in orthotopic liver transplantation. However, liver biopsy is still the primary method for HIRI evaluation in clinical practice despite its numerous complications and shortcomings such as hemo...
Article
Background and purpose: Macrophages regulate iron homeostasis in the liver and play important role in hepatic ischemia/reperfusion (I/R) injury. The aim of this study was to explore the role of macrophages in iron overload-related hepatocyte damage during liver I/R. Experimental approach: Liver biopsys from patients undergoing partial hepatectom...
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Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting in unacceptably high mortality. However, effective preventive treatments are still lacking. We hypothesized that pretreatment with lipoxin A4 (LXA4), known to promote inflammation resolution, may attenuate septic AKI via blocking crosstalk between inflammation and cel...
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Full-text available
Background Sepsis is the leading cause of hospitalization and death in the intensive care unit. It is vital to identify high-risk patients with poor prognosis in the early stages of sepsis. We aimed to investigate the prognostic value of serum phosphorus levels for sepsis. Methods The data of 4767 patients with sepsis were collected from the Multi...
Preprint
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Background: This systematic review and meta-analysis aimed to evaluate the effect of dexmedetomidine on lung function and prognosis. Methods: We searched PubMed, Embase and the Cochrane Library from inception to January 30, 2020 following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement guidelines. Randomized...
Article
In this study, the expression pattern of CsPAP-fib under different night temperature conditions (12 °C, 18 °C, and 24 °C) was analyzed using qRT-PCR, the subcellular localization of CsPAP-fib protein was determined, and sense and antisense CsPAP-fib were transformed into cucumber. The first node with female flowers and the female flower rate were c...

Citations

... Predictive models have been developed with good overall sensitivity to predict post-transplantation sepsis. 89 In addition, patients on the wait list who have high bradenscore, which is used to identify the risk of pressure sores, have a higher post-transplantation length of hospital stay. 90 Furthermore, pre-surgery mechanically ventilated patients with PaO 2 /FiO 2 # 200 mm Hg have longer post-transplantation ICU stay and outcomes. ...
... PTPN20 has been shown to have differential expression across cancer types, suggesting that it may have distinct roles in different cancer types. Specifically, while the expression of PTPN20 was reduced in colorectal cancer (19), PTPN20 levels showed no change between acute myeloid leukemia cell and normal cells (41). In esophageal carcinoma, PTPN20 was upregulated and associated with both the TNM stage and N stage. ...
... Tumor cells take up and use more glucose than they need, which is known as the Warburg effect (22). Recently, the amino acid dependence of tumor cells has received more and more attention (23). Amino acids have been demonstrated to be the dominant nitrogen source for hexosamines, nucleotides, and other nitrogenous compounds in rapidly proliferating cells (24,25). ...
... Applying the herbicide bensulfuron-methyl on cucumber decreased the F V /F M ratio, minimal fluorescence (F 0 ), the actual efficiency of PSII (ΦPSII) and electron transport rate (ETR) parameters [28]. The F V /F M ratio and ΦPSII are reported as stress indicators in response to insecticide application [29]. ...
... The analgesic effect was comparable to that of continuous infusion of 0.2% ropivacaine for 48 h [23]. Poloxamer 407 and polycaprolactone electrospun fibers have been used as excipients to prepare ropivacaine hydrogels that blocked rat nerves for more than 30 h [24]. However, the safety of new excipients has yet to be fully elucidated. ...
... Chen et al. (19) studied and analyzed cells, and found that during renal ischemia/reperfusion, the intracellular reactive oxygen species increased, but the endogenous anti-oxidants did not increase accordingly, which led to the accumulation of reactive oxygen species in the cells, thus damaging the cells. In the process of inflammatory reaction, the oxygen free radicals produced in the body will increase explosively, which is difficult to be cleared by SOD, CAT, GSH, and other anti-oxidant enzymes in the body, thus leading to the accumulation of active oxygen clusters in the kidney tissue, the level of inflammatory factors will increase, and the degree of organ damage will increase (20). ...
... In recent years, the role of hepatic ferroptosis in the onset and Ivyspring International Publisher development of NAFLD has been emphasized. Hepatocyte ferroptosis may worsen NAFLD by raising the likelihood of hepatocyte swelling, inflammation, and fibrosis, thus speeding up the progress from simple steatosis to NASH [8,9]. Therefore, inhibiting hepatic ferroptosis is likely to be a therapeutic target for NAFLD. ...
... Furthermore, specifically knocking out the myeloid differentiation factor (Myd88) gene of TECs can reduce not only pro-inflammatory factors, interstitial infiltration, and fibrosis but also senescent cell aggregation and renal tubular damage, demonstrating that the TLR/Myd88/NF-κB pathway is an important pathway in mediating cellular senescence in TECs. Chen et al. [51] discovered that in the early stages of SAKI, Lipoxin A4 exerts anti-aging and anti-inflammatory effects via the PPAR-γ/NF-κB pathway, helping to improve renal function. ...
... An interesting observation is that 80% of septic patients have hypophosphatemia associated with elevated concentrations of inflammatory cytokines such as tumor necrosis factor (TNF) alpha and interleukin (IL)-6 and other inflammatory cytokines included in cytokine storm in COVID-19 [56,57]. Studies concerning impact of phosphate concentrations on mortality are inconclusive [58,59]. Our results suggest a link between hypophosphatemia and delirium and indirectly with mortality, as shown by studies in 6190 patients where hypophosphatemia is an independent risk factor for sepsis mortality [58]. ...
... Notably, SlFBN11 showed the most significant response to ABA, and its expression increased 27.0 times at 12 h and 9.7 times at 24 h compared with the 0 h, suggesting that this gene was likely to involved in the ABA signal pathway. DISCUSSION FBN family proteins were early discovered in fibrils of chromoplasts (Deruère et al., 1994) and were involved in the various plant tissues growth and development, stress and hormone signal response (Jiang et al., 2020;Liu et al., 2018). In recent years, FBN gene families have been identified in several plants, such as rice (Li et al., 2020), cucumber (Kim et al., 2018 and wheat (Jiang et al., 2020). ...