Jin Kang's research while affiliated with The Second Xiangya Hospital of Central South University and other places
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Publications (8)
Background
Alzheimer’s disease (AD) is the most common form of dementia characterized by a prominent cognitive deterioration of sufficient magnitude to impair daily living. Increasing studies indicate that non-coding RNAs (ncRNAs) are involved in ferroptosis and AD progression. However, the role of ferroptosis-related ncRNAs in AD remains unexplore...
Background
The diabetes patients have a higher incidence of malignant tumors than people without diabetes. However, the molecular mechanisms of the relationship between diabetes and malignant tumors remain largely unknown.
Methods
By exploiting available public databases, diabetes and cancer-related genes (DCRGs) were screened, and a diabetes-base...
Background
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects multiple systems and increases the risk of mental disorders such as depression and anxiety. We conducted an observational, single-center, cross-sectional study to investigate the relationship between depression, anxiety, and SLE disease activity.
Methods
The Patien...
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Vaccination is key in mastering the COVID-19 pandemic. Data on attitudes towards and safety of the SARS-CoV-2 inactivated vaccines in patients with systemic lupus erythematosus (SLE) are limited. A post-vaccination cross-sectional survey was conducted to obtain data on attitudes towards and safety of the SARS-CoV-2 inactivated vaccines in SLE patie...
Objective
We conducted the following cross-sectional study to comprehensively assess the anxiety among Chinese international students who studied online during the COVID-19 pandemic and its influencing factors.
Methods
Questionnaires were distributed through “Sojump,” and a total of 1,090 valid questionnaires were collected. The questionnaire was...
Background:
Approximately 30% of patients with rheumatoid arthritis (RA) respond poorly to combination therapy of multiple drugs. The molecular mechanisms of different responses to methotrexate + leflunomide + infliximab therapy in patients with RA were explored in this study.
Methods:
Infliximab was administered to patients with RA whose diseas...
Objective:
To explore the main components and unravel the potential mechanism of simiao pill (SM) on rheumatoid arthritis (RA) based on network pharmacological analysis and molecular docking.
Methods:
Related compounds were obtained from TCMSP and BATMAN-TCM database. Oral bioavailability and drug-likeness were then screened by using absorption,...
Citations
... Recent systematic reviews and meta-analyses suggest that the overall prevalence of depression and anxiety among SLE patients is 35%, respectively 25.8%, with ranges from 8.7% to 78.6% for depression and from 1.1% to 71.4% for anxiety, but the authors emphasize that the heterogeneity of the assessment's scales used for these two majors neuropsychiatric SLE manifestations make challenging to identify a precise prevalence of anxiety and depression among SLE patients [9]. At the same time recent cross-sectional research results on SLE patients showed depression in 61.5% of patients and anxiety in 54.4% and suggested a cut-off value for SLEDAI of 8.5 for the increased risk of neuropsychiatric SLE manifestations [37]. This research indicates a strong correlation between depression symptoms and severe disability in social participation, interpersonal relationships and life abilities. ...
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... A cross-sectional survey by Tang et al investigated postvaccination adverse events and SLE flares in 188 cases with SLE and 190 healthy individuals who received at least one dose of the SARS-CoV-2 inactivated vaccine. The adverse events were negligible and there were no severe adverse events in both groups of SLE cases and healthy individuals after SARS-CoV-2 inactivated vaccine (31). This is in sharp contrast to other mentioned reports with increased side effects and flares with use of mRNA COVID-19 vaccines such as Pfizer/BioNTech (BNT162b2) (12)(13)(14)17,18,(20)(21)(22)(23)25,26), AZD1222 vaccine (15,16) and Moderna (19,24). ...
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... Procrastination in online learning refers to online learners' procrastination, slackness, and anxiety when they are not under face-to-face supervision. Under the influence of COVID-19 closed management, the psychological state of learners will also be greatly affected, resulting in online learning delays [40]. Online learning truancy is more serious. ...
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... It has been indicated that serotransferrin-related molecules may be a promising method for investigating refractory RA (104). In addition, Tumor necrosis factor (TNF) signaling exerts its effect on fibroblasts in different manners to protect them from ferroptosis, such as promoting cystine uptake and increasing the biosynthesis of GSH (105). ...
... Simiao pill, a TCM formula, consists of Rhizoma Atractylodis, Cortex Phellodendri, Radix Achyranthis Bidentatae, and Semen Coicis at the ratio of 1 : 2 : 1 : 2 [16,17]. Pharmacological research has indicated that Simiao pill contains a variety of natural active compounds, such as flavonoids and phenols [18]. Interestingly, recent studies have demonstrated that some phytochemicals including flavonoids and phenols possess antioxidative activity, which benefit to the treatment of various diseases and health care [13,19,20]. ...
