Jian-Bin Guo’s research while affiliated with Fujian Medical University and other places

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Publications (1)


Ganoderic acid A form Ganoderma lucidum ameliorates lipid metabolism and alters gut microbiota composition in hyperlipidemic mice fed a high-fat diet
  • Article

June 2020

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120 Reads

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76 Citations

Food & Function

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Jian-Bin Guo

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Bin-Yu Liu

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[...]

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Xu-Cong Lv

Ganoderic acid A (GA) is one of most abundant triterpenoids in Ganoderma lucidum, and has been proved to possess a wide range of beneficial health effects. The aim of the current study was...

Citations (1)


... Recently, GAA was reported to improve Alzheimer's disease via the Th17-Tregs axis, regulate lipid metabolism in mice with nonalcoholic fatty liver, and inhibit inflammation in mice with pulmonary fibrosis [34][35][36] . A single study examined the relationship between GAA and cellular senescence in Aβ25-35-stimulated mice hippocampal neuronal cell line, which was designed to mimic the characteristics of Alzheimer's disease 37 . ...

Reference:

High-content screening identifies ganoderic acid A as a senotherapeutic to prevent cellular senescence and extend healthspan in preclinical models
Ganoderic acid A form Ganoderma lucidum ameliorates lipid metabolism and alters gut microbiota composition in hyperlipidemic mice fed a high-fat diet
  • Citing Article
  • June 2020

Food & Function