Jesper Fjølner's research while affiliated with Regionspsykiatrien Viborg-Skive and other places

Publications (11)

Article
Full-text available
Background Noninvasive ventilation (NIV) is a promising alternative to invasive mechanical ventilation (IMV) with a particular importance amidst the shortage of intensive care unit (ICU) beds during the COVID-19 pandemic. We aimed to evaluate the use of NIV in Europe and factors associated with outcomes of patients treated with NIV. Methods This i...
Article
Full-text available
Purpose: Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease (COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates the association of the Activities of Daily Living (ADL) with the outcome in this vulnerable patient group. Methods: The COVIP study is a prospective internatio...
Article
Full-text available
Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have been mostly affected during the initial surge in 2020. Methods: This prospective international observation study (The COVIP study...
Article
Full-text available
Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have been mostly affected during the initial surge in 2020. Methods: This prospective international observation study (The COVIP study...
Article
Full-text available
Background: The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score...
Article
Full-text available
Background: The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both the triage into intensive care, and decisions r...
Preprint
Full-text available
Background The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both the triage into intensive care, and decisions re...
Article
Full-text available
Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have been mostly affected during the initial surge in 2020. Methods: This prospective international observation study (The COVIP study...
Article
In the original publication Dr Patrick Meybohm of the Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Frankfurt University Hospital, Frankfurt, Germany was inadvertently omitted from the list of investigators.

Citations

... The highest mortality rates (40%e80%) are reported in elderly patients admitted to the ICU [14,15,31]. Because of this finding, some intensivists were initially discouraged from admitting elderly patients to the ICU and used age as an exclusion criterion for ICU care [33]. ...
... Lactate has been studied over time in patients with septic shock, and serum lactate is an important prognostic factor that reflects decreased oxygen delivery and tissue hypoperfusion [8][9][10] . The finding of hyperlactatemia in patients with normal tissue perfusion and oxygen delivery additionally suggests that an overstimulation of the Na+-K+-ATPase leads to an increased lactate production in septic patients similar to hypokalemia. ...
... Due to multimorbidity and frailty, critically ill elderly patients have a particularly poor prognosis [13]. Similar analyses among patients with COVID-19 confirmed that increasing age and degree of frailty are related to worse outcomes in this population [14]. ...
... 16 The geriatric concept of frailty is gaining interest in triage 17 and is associated with outcome 18,19 and is strongly associated with outcome in elderly COVID-19 patients. 20 According to most COVID-19 ethical guidelines, age must not be considered the primary reason for triage but remains a relevant factor when estimating long-term prognosis. 11 However, if relevant patient information and history is scarce, weight may be placed on age as a triage criterion as it is easily obtainable. ...
... Frailty is related to the prognosis of elderly patients. A multicenter study of elderly COVID-19 patients ≥70 years old showed that higher frailty was associated with higher 30-day mortality and a higher rate of treatment limitation [32]. Pranata et al. and Aliberti et al. [33] also showed that higher clinical frailty scores were associated with higher mortality [16]. ...