Jens D. Rollnik's research while affiliated with Hannover Medical School and other places

Publications (181)

Article
Background: Falls are highly frequent among neurological patients during rehabilitation and subsequent risk assessments are crucial to prevent falls. Objective: This study aims to determine the predictive values of the Hessisch Oldendorf Risk of Falling Scale (HOSS, "Hessisch Oldendorfer Sturzrisiko Skala") for two timeframes: the first month of...
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The present study was aimed at examining thyroid hormones and other clinical factors to improve the accuracy of outcome prediction among critically ill patients undergoing early neurological rehabilitation. Patients consecutively admitted to an intensive or intermediate care unit were screened for eligibility. Serum levels of free triiodothyronine...
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Background The present study intended to analyze the outcome of patients with severe brain injury one-year after discharge from early rehabilitation. Methods Early neurological rehabilitation patients admitted to intensive or intermediate care units and discharged between June 2018 and May 2020 were screened for eligibility. The level of conscious...
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Background: Upper limb dysfunction is a frequent complication after stroke impairing outcome. Inhibitory repetitive transcranial magnetic stimulation (rTMS) applied over the contralesional hemisphere is supposed to enhance the positive effects of conventional rehabilitative treatment. Objective: This double-blind randomized placebo-controlled tr...
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Background: Clinical ethics committees (CECs) have been implemented in German clinics since the 1990s. Besides problems with the integration into clinical routines, CECs result in an enrichment and relief for employees and relatives. Investigating the current status of CECs in specialized neurological clinics is crucial because changes in therapy...
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Objective This study aims to further validate the Hessisch Oldendorf Risk of Falling Scale (HOSS) for neurological rehabilitation patients. Design The overall scale performance and fall rate was calculated in a retrospective data analysis. Setting The study was performed in a subacute care facility during inpatient neurological rehabilitation. S...
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Passive listening to music is associated with several psychological and physical benefits in both, healthy and diseased populations. In this fMRI study, we examined whether preferred music has effects on the functional connectivity within resting-state networks related to consciousness. Thirteen patients in unresponsive wakefulness syndrome (UWS) a...
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Background The aim of the study was to determine the role of the Coma Recovery Scale-Revised (CRS-R) in the prediction of functional status at the end of neurological early rehabilitative treatment. Methods Patients consecutively admitted to intensive or intermediate care units of a neurological rehabilitation center were enrolled in the study. Co...
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There is empirical evidence that expected yet not current affect predicts decisions. However, common research designs in affective decision-making show consistent methodological problems (e.g., conceptualization of different emotion concepts; measuring only emotional valence, but not arousal). We developed a gambling task that systematically varied...
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Zusammenfassung Neurologisch-neurochirurgische Frührehabilitanden sind klinisch oft so schwer betroffen, dass sie neben der frührehabilitativen Behandlung auch von der mechanischen Beatmung entwöhnt werden müssen. In einer Umfrage der Deutschen Gesellschaft für Neurorehabilitation (DGNR) wurden neurologische Weaningzentren gebeten, Informationen zu...
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Zusammenfassung Die vorliegende Übersichtsarbeit beschäftigt sich mit dem Myalgie-Faszikulations-Krampus-Syndrom (MFKS), einer gutartigen Erkrankung, die zu den Hyperexzitabilitätssyndromen des peripheren Nervensystems gezählt wird. Der Artikel stellt die Klinik, Pathophysiologie, Differenzialdiagnostik und Therapie dar und illustriert das MFKS mit...
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The SARS-CoV-2 pandemic threatens health care providers and society. For planning of treatment capacities, it is of major importance to obtain reliable information on infection and fatality rates of the novel coronavirus. A German community study, the so-called Heinsberg study, found a 5-fold higher infection rate (and thus a remarkably lower fatal...
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Background: By identifying occupational problems, job-related therapies may be included in rehabilitation at an early stage, increasing the return-to-work rate. The aim of the present study was to examine whether occupational problems that were identified were associated with the employment status six months after inpatient rehabilitation. Method...
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An vielen Rehabilitationskliniken und Akutkrankenhäusern wurden in den letzten Jahrzehnten auf die – insbesondere rehabilitativen – Bedürfnisse schwerkranker neurologischer Patienten spezialisierte Intensiv- und Beatmungsstationen aufgebaut. Intensivmedizinische Behandlung, Beatmungsentwöhnung und Rehabilitation müssen dort gleichzeitig geleistet w...
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Zusammenfassung Das vorliegende Review beschäftigt sich mit kognitiven Störungen und Teilhabebeeinträchtigungen nach aneurysmatischen Subarachnoidalblutungen (aSAB). Diese können auch ohne den Nachweis einer substanziellen Hirnschädigung in der neuropsychologisch zu erwartenden Region auftreten. Als Ursache für diese Diskrepanz gelten neuroinflamma...
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Neurologic music therapy in rehabilitation of stroke patients has been shown to be a promising supplement to the often strenuous conventional rehabilitation strategies. The aim of this study was threefold: (i) replicate results from a previous study with a sample from one clinic (henceforth called Site 1; N = 12) using an already established record...
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Zusammenfassung Methicillin-resistente Staphylococcus-aureus-Stämme (MRSA) haben in der neurologisch-neurochirurgischen Frührehabilitation eine erhebliche medizinische und ökonomische Relevanz. Es ist wichtig, MRSA-Träger möglichst rasch nach Aufnahme zu identifizieren, um Transmissionen zu verhindern und Isolierungs- sowie Dekolonisierungsmaßnahme...
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Background: Paroxysmal Sympathetic Hyperactivity (PSH) is a frequently observed condition among critically ill patients on intensive care units. According to different studies, PSH is associated with worse recovery and increased mortality in acute-care facilities. In this monocentric, retrospective case-control study, we investigated whether this...
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Background & aims Approximately 55% of neurological and neurosurgical early rehabilitation (NNER) patients are in need of enteral nutrition, but long-term nutritional assessment of these critically ill patients is suboptimal. Therefore, this study analyzed the effect of an individual nutritional assessment on weight changes during rehabilitation an...
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Zusammenfassung Einleitung Die Untersuchung diente der Erhebung der Versorgungssituation in der neurologisch-neurochirurgischen Frührehabilitation (NNFR) in den Bundesländern Niedersachen (NDS) und Bremen (HB). Methodik Zur Untersuchung wurden alle Anmeldungen aus Akutkliniken zur NNFR in NDS / HB innerhalb einer Periode von zwei Wochen jeweils im...
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Background & aims: Studies focusing on the nutritional status of neurological and neurosurgical early rehabilitation (NNER) patients are limited. The aim of the current study was to determine the nutritional status of NNER patients upon admission, to observe weight changes and to investigate the influence of nutritional status on complications and...
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Zusammenfassung Hintergrund In der neurologisch-neurochirurgischen Frührehabilitation (NNFR) gehen viele Krankheitsbilder mit einem erhöhten Risiko von Pneumonien einher. Vor einigen Jahren wurde die Disziplin der Atmungstherapie etabliert, um respiratorische Komplikationen abzuwenden. Derzeit gibt es allerdings keine Studien, die die Effektivität...
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Background: Studies analyzing risk factors of weaning failure in neurological and neurosurgical early rehabilitation (NNER) patients are rare. Aim: The aim of this study was to identify clinical factors influencing the weaning of NNER patients. Design: An observational, retrospective data analysis of a German multi-center study was performed....
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Zusammenfassung Die motivierende Wirkung der Musik kann überaus fruchtbar in der Neurorehabilitation von gestörten Hand- und Armfunktionen genutzt werden. Wir stellen zwei Ansätze vor, nämlich das „Klaviertraining“ und das „Sonifikations“-Training, in denen diese neurologische Musiktherapie pragmatisch umgesetzt wird. Ein Ausblick auf zukünftige Pr...
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Background & aims: Diarrhea has negative consequences for patients, health care staff and health care costs when neurological patients are fed enterally over long periods. We examined the effect of tube feeding with natural foods in reducing the number of fluid stool evacuations and diarrhea in critically ill neurological patients. Methods: A mu...
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Objective: To calculate scale performance of the newly developed Hessisch Oldendorf Fall Risk Scale (HOSS) for classifying fallers and non-fallers in comparison with the Risk of Falling Scale by Huhn (FSH), a frequently used assessment tool. Design: A prospective observational trail was conducted. Setting: The study was performed in a large sp...
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Background Neurological and neurosurgical early rehabilitation (NNER) is a specialized treatment option for patients with severe neurological disorders. The present study investigated whether thyroid hormone levels on admission have an impact on the outcome of NNER patients. Method The study included 500 NNER patients who were admitted to the BDH-...
Article
Prolonged weaning of patients with neurological or neurosurgery disorders is associated with specific characteristics, which are taken into account by the German Society for Neurorehabilitation (DGNR) in its own guideline. The current S2k guideline of the German Society for Pneumology and Respiratory Medicine is referred to explicitly with regard t...
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In Germany, medical-occupational rehabilitation represents an essential link between rehabilitation programs focusing either on medical or occupational rehabilitation. Its main objective is return to work. The current study presents the vocational integration 5 years after medical-occupational rehabilitation and determines possible prognostic facto...
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Background: There is little known about the factors influencing the weaning process of long-term mechanically ventilated patients in the neurological early rehabilitation. Aim: To identify salient clinical and neurophysiological variables with impact upon weaning from mechanical ventilation during neurological and neurosurgical early rehabilitat...
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Background Colonization or infection with multi-drug resistant (MDR) bacteria is considered detrimental to the outcome of neurological and neurosurgical early rehabilitation patients. Methods In a German multi-center study, 754 neurological early rehabilitation patients were enrolled and and reviewed in respect to MDR status, length of stay (LOS) a...
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Zusammenfassung Die Beatmungsentwöhnung von neurologisch-neurochirurgischen Frührehabilitanden stellt besondere Anforderungen an spezialisierte Rehabilitationseinrichtungen. Begleitend zu den üblichen frührehabilitativen Therapien stellt die Entwöhnung vom Respirator ein wichtiges Teilhabeziel dar, das die multidisziplinäre Zusammenarbeit von Ärzte...
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Background: Neurological and neurosurgical early rehabilitation (NNER) represents a special treatment for patients with severe neurological disorders. The present study investigated whether and how patient and treatment characteristics positively influence the outcome during NNER treatment. Method: The study included 573 phase-B-patients who were a...
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Die okuläre Myositis stellt ein seltenes Krankheitsbild dar, bei dem es zu einer schmerzhaften Diplopie, sehr selten auch zu einem Visusverlust kommt. In der Darstellung der vorhandenen Literatur wird insbesondere auf die Differenzialdiagnostik eingegangen. Im vorliegenden Fall erkrankte eine 80-jährige Patientin, die über einen langsam progredient...
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Background Critical illness polyneuropathy (CIP) is a complex disease affecting 30–70% of critically ill patients. Methods Clinical (Barthel index, length of stay (LOS), morbidity, duration of mechanical ventilation, routine lab results) and neurophysiological (neurography) data of 191 patients admitted to neurological early rehabilitation and dia...
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Einleitung: Das Würzburger Screening (WS) wird von der Deutschen Rentenversicherung zur Identifikation beruflicher Problemlagen (BPL) in der Rehabilitation empfohlen. Es ist allerdings unklar, ob es auch für neurologische Rehabilitanden verwendbar ist. Methodik: Daten von 347 neurologischen Rehabilitanden in der Anschlussrehabilitation wurden unter...
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Zusammenfassung Hintergrund: Die Arbeitsgruppe neurologischneurochirurgische Frührehabilitation (NNFR) hat im Jahr 2002 und im Jahr 2014 Verlaufsuntersuchungen von Patienten der NNFR durchgeführt. Die Studie stellt die Ergebnisse des Vergleiches aus den beiden Studien vor. Patienten und Methoden: Die Rehabilitationsverläufe in der NNFR wurden im J...
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The authors' aim was to investigate the changes of corticospinal excitability during kinesthetic illusions induced by tendon vibration. Motor-evoked potentials in response to transcranial magnetic stimulation were recorded from the vibrated flexor carpi radialis and its antagonist, extensor carpi radialis. The illusions were evoked under vision con...
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Background Evaluation of functional status is difficult in neurological and neurosurgical early rehabilitation patients. The Early Rehabilitation Index (ERI) was introduced in Germany over 20 years ago, but since then validation studies are lacking. The ERI (range −325 to 0 points) includes highly relevant items including the necessity of intermitt...
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Gross-motor impairments are common after stroke, but efficient and motivating therapies for these impairments are scarce. We present an innovative musical sonification therapy especially designed to retrain patients' gross-motor functions. Sonification should motivate patients and provides additional sensory input informing about relative limb posi...
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Background In Germany, neurological-neurosurgical early rehabilitation is well established in the treatment of severe neurological diseases. To develop quality standards, knowledge of the current rehabilitation course is required. Patients and Methods A retrospective analysis was performed on the course of rehabilitation from patients in an early n...
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Purpose: Learning to play musical instruments such as piano was previously shown to benefit post-stroke motor rehabilitation. Previous work hypothesised that the mechanism of this rehabilitation is that patients use auditory feedback to correct their movements and therefore show motor learning. We tested this hypothesis by manipulating the auditor...
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Ziel der Studie: Stürze stellen während der neurologischen Rehabilitation ein erhebliches Risiko dar. Die Identifizierung sturzgefährdeter Rehabilitanden ist mittels bestehender Sturzrisiko-Skalen nur in einem unzureichenden Maß möglich. Daher war es Ziel dieser Studie eine Risiko-Skala für neurologische Rehabilitanden zu entwickeln. Methodik: Auf...
Chapter
Neurologische Patienten sollten zügig einer qualifizierten Frührehabilitation zugeführt werden. Schon in der Akutbehandlung, also beim beatmeten Patienten auf der Intensivstation, sollten rehabilitative Behandlungsansätze angewandt werden, etwa therapeutisch-aktivierende Pflege mit speziellen Lagerungstechniken, basale Stimulation, Physiotherapie....
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Background: So far, the role of clinical neurophysiology in the prediction of outcome from neurological and neurosurgical early rehabilitation is unclear. Methods: Clinical and neurophysiological data of a large sample of 803 early rehabilitation cases of the BDH-Clinic Hessisch Oldendorf in Northern Germany have been carefully reviewed. Most pa...
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Background It is difficult to assess neurological and neurosurgical early rehabilitation patients comprehensively. Available scales focus on activities of daily living (Barthel (BI) and Early Rehabilitation Barthel Index (ERBI)) or wakefulness (Glasgow Coma Scale (GCS), Coma Remission Scale (CRS)) while cognitive items are missing. Methods The Ear...
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The prevalence of patients suffering from hypoxic brain damage is increasing. Long-term outcome data and prognostic factors for either poor or good outcome are lacking. This retrospective study included 93 patients with hypoxic brain damage undergoing neurological early rehabilitation [length of stay: 108.5 (81.9) days]. Clinical data, validated ou...
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Huntington's disease (HD) is a chronic neurodegenerative disease for which as yet no disease-modifying therapy is available. Even at the early stage of the disease, HD patients suffer from motor and cognitive impairments. They are in need of physical, occupational and speech therapy or (inpatient) multidisciplinary rehabilitation. This paper review...
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Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by hyperkinetic movements, psychiatric (e.g. depression and psychosis) and cognitive symptoms (frontal lobe dementia). In Germany approximately 8000 patients suffer from HD. The paper reviews the clinical course, epidemiology, genetics, differential diagnoses, patho...
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Gross-motor impairments are common after stroke, but efficacious and motivating therapies for these impairments are scarce. We present a novel musical sonification therapy especially designed to retrain gross-motor functions. Four stroke patients were included in a clinical pre-post feasibility study and were trained with our sonification training....
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Unilateral cerebral ischemia of the hippocampus is very rare. This paper reviews the literature and presents the case of a 59-year-old woman with an amnestic syndrome due to a left hippocampal stroke. The patient suffered from retrograde amnesia which was most severe over the 2 days prior to presenting and a slight anterograde amnesia. In addition,...
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Colonization with multidrug-resistant germs, in particular methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum betalactamase producing bacteria (ESBL), is an emerging threat in early neurological rehabilitation. This study examined whether colonization with ESBL bacteria had deteriorating effects on neurological rehabilitation...
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Introduction: Nursing is most important in neurological early rehabilitation to achieve a good outcome. In the present study, the validity of the catalogue of the "Working Group on Nursing in Early Rehabilitation" (AGnFP) has been examined. Methods: 54 neurological early rehabilitation patients (mean age 68.3 (14.7) years) have been enrolled. All n...
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Despite cerebral stroke being one of the main causes of acquired impairments of motor skills worldwide, well-established therapies to improve motor functions are sparse. Recently, attempts have been made to improve gross motor rehabilitation by mapping patient movements to sound, termed sonification. Sonification provides additional sensory input,...
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Background Genetic factors as predictor of the individual outcome of drug therapy is one aim of personalized medicine approaches. Case presentation We report a drug metabolism based analysis of genetic polymorphisms in a Caucasian patient receiving fluvastatin and telmisartan experiencing myotoxicity (myalgia and moderate creatine kinase elevation...
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Multidrug-resistant germs are an increasing problem in neurological and neurosurgical early rehabilitation but reliable data is missing. The present study examined the prevalence of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and multidrug-resistant gram negative germs (MRGN) in a German neurological...
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Das Hessisch Oldendorfer ICF-Assessment (HOIA) stellt einen Vorschlag zur ICF-konformen Dokumentation des Aufnahmebefundes, der Definition von Therapiezielen (mit daraus abgeleiteter Therapieplanung) und der Therapiezielerreichung in der neurologisch-neurochirurgischen Rehabilitation dar. Um die Praktikabilitat, Validitat und Anderungssensitivitat...
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This review presents an overview of the use of music therapy in neurological early rehabilitation of patients with coma and other disorders of consciousness (DOC) such as unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS). There is evidence that patients suffering from UWS show emotional processing of auditory information, s...
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Background: Music-supported therapy has been shown to be an effective tool for rehabilitation of motor deficits after stroke. A unique feature of music performance is that it is inherently social: music can be played together in synchrony. Aim: The present study explored the potential of synchronized music playing during therapy, asking whether syn...
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Colonization with MRSA is believed to have deteriorating effects on neurological rehabilitation patients because MRSA carriers need to be isolated. Medical records of neurological early rehabilitation patients (most of them after stroke) admitted to a large rehabilitation facility in Northern Germany in 2010 have been carefully reviewed with respec...
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Multidrug-resistant pathogens are an increasing problem in neurological rehabilitation, but infectious diarrhea caused by Clostridium difficile and norovirus is relevant, too, because it may significantly interfere with therapy during rehabilitation. Since reliable data is missing, the present study examined the incidence of Clostridium difficile a...