Janalynn Beste’s research while affiliated with University of North Carolina at Chapel Hill and other places

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Publications (3)


Clinical inquiry. Do antibiotics shorten symptoms in patients with purulent nasal discharge?
  • Literature Review

April 2012

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16 Reads

The Journal of family practice

Amanda Ruxton

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Claude Roofian

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Kevin E Johnson

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[...]

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Donna Flake

For most patients with purulent nasal discharge, antibiotics don't decrease symptom duration; they do increase adverse events. Researchers in the field don't recommend using antibiotics as routine treatment for purulent rhinorrhea associated with symptoms of upper respiratory infection.


Antidepressant use during pregnancy. FPIN’s clinical inquiries

May 2011

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36 Reads

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4 Citations

American Family Physician

Clinical Inquiries provides answers to questions submitted by practicing family physicians to the Family Physicians Inquiries Network (FPIN). Members of the network select questions based on their relevance to family medicine. Answers are drawn from an approved set of evidence-based resources and undergo peer review. The strength of recommendations and the level of evidence for individual studies are rated using criteria developed by the Evidence-Based Medicine Working Group


Citations (2)


... Except for congenital abnormalities and developmental delays, for which the data was interpreted as conflicting, physicians were more likely to indicate that adverse fetal and neonatal outcomes had no evidence of an association or evidence of no association with SSRI use overall. Although available data suggests low overall risk of teratogenic effects due to antidepressant use, risks for harm have been found (Patel et al. 2011;Reefhuis et al. 2015;Lattimore et al. 2005), and the FDA's current position is that the "potential risk with SSRI use during pregnancy remains unknown" (US FDA 2012). Fig. 3 Responses to "What is your interpretation of the current evidence on the impact of SSRI use during pregnancy on the listed fetal and neonatal outcomes?" ...

Reference:

Prenatal depression screening and antidepressant prescription: obstetrician-gynecologists’ practices, opinions, and interpretation of evidence
Antidepressant use during pregnancy. FPIN’s clinical inquiries
  • Citing Article
  • May 2011

American Family Physician

... Oxytocin acts quickly and effectively with minimal adverse effects and can be used in all women, which makes it the main interven- tion for reducing PPH and is the first uterotonic drug option (23). The administration of oxytocin during the TSL reduces the risk of PPH by 40% (24). Immediately after fetal delivery, starting intravenous infusion of 20 IU of oxytocin in 500 mL RL and given within 2 hours is the routine protocol in our institute for AMTSL. ...

Clinical inquiries. Prophylactic oxytocin: Before or after placental delivery?
  • Citing Article
  • January 2009

The Journal of family practice