Jan Wadstein's scientific contributions

Publications (5)

Article
Full-text available
Skin ageing is a progressive, but modifiable, multi-factorial disorder that involves all the skin’s tissues. Due to its wide range of physiological and psychosocial complications, skin ageing requires rigorous clinical attention. In this review, we aim to encourage clinicians to consider skin ageing as a disorder and suggest a novel, dual approach...
Preprint
Skin ageing is a progressive but modifiable, multi-factorial disorder that involves all skin tissues. Pertaining to its wide range of physiological and psychosocial complications, skin ageing requires rigorous clinical attention. Topical retinoids and per-oral proteoglycans are promising, non-invasive, therapeutic modalities. To overcome the low bi...
Article
Full-text available
p> Background: Skin psoriasis is a serious inflammatory disorder with increased risk of rheumatic, cardiometabolic and psychosocial complications. At present, >50% of patients are dissatisfied with their treatment; thus, novel approaches are in high clinical demand. Retinoids are a major group of anti-psoriatic compounds; nonetheless, dose-dependen...
Article
Full-text available
Follicular proteoglycans are key players with structural, functional, and regulatory roles in the growth and cycling behaviour of the hair follicles. The expression pattern of specific proteoglycans is strongly correlated with follicular phase transitions, which further affirms their functional involvement. Research shows that bioactive proteoglyca...
Article
Full-text available
TREATING FEMALE DIFFUSE HAIR LOSS

Citations

... The oral administration of natural proteoglycans and glycosaminoglycans is an emerging therapeutic method that has been tried for the treatment of a variety of human disorders including, but not limited to, hair loss disorders [57], osteoarthritis [58] and skin psoriasis [59]. Pertaining to the integral role of 'proteoglycan dysmetabolism' in the pathogenesis of both chronological and accelerated skin ageing, the oral administration of specific bioactive proteoglycans is deemed to be a relevant anti-ageing approach. ...