Jan J Barendregt's research while affiliated with The University of Queensland and other places
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Publications (176)
Parenting programmes are the recommended treatments of conduct disorders (CD) in children, but little is known about their longer term cost-effectiveness. This study aimed to evaluate the population cost-effectiveness of one of the most researched evidence-based parenting programmes, the Triple P—Positive Parenting Programme, delivered in a group a...
Detection of publication and related biases remains suboptimal and threatens the validity and interpretation of meta-analytical findings. When bias is present, it usually differentially affects small and large studies manifesting as an association between precision and effect size and therefore visual asymmetry of conventional funnel plots. This as...
Indirect comparison methods are used to measure the effect of two treatments that were each compared against a similar control group in a meta-analysis. The network meta-analysis method extends this to multiple treatments which are assessed simultaneously. Currently, there exist Bayesian and multivariate modelling approaches to these analyses, but...
Background
Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and insecticidal-treated bed nets), indoor residual spraying (IRS), prophylactic drugs (PD), and untreated nets (UN). However,...
Background
Studies have consistently shown that subthreshold depression is associated with an increased risk of developing major depression. However, no study has yet calculated a pooled estimate that quantifies the magnitude of this risk across multiple studies.
Methods
We conducted a systematic review to identify longitudinal cohort studies cont...
Background:
Anorexia nervosa (AN) is a prevalent, serious mental disorder. We aimed to evaluate the cost-effectiveness of family-based treatment (FBT) compared to adolescent-focused individual therapy (AFT) or no intervention within the Australian healthcare system.
Method:
A Markov model was developed to estimate the cost and disability-adjuste...
Each year up to 20 000 systematic reviews and meta-analyses are published whose results influence healthcare decisions, thus making the robustness and reliability of meta-analytic methods one of the world's top clinical and public health priorities. The evidence synthesis makes use of either fixed-effect or random-effects statistical methods. The f...
Background: Screening programs consistently underserve indigenous populations despite a higher overall burden of cancer. In this study, we explore the likely health gains and cost-effectiveness of a national colorectal cancer screening program for the indigenous Māori population of New Zealand (NZ).
Methods: A Markov model estimated: health benefit...
Background:
Eating disorders (EDs), including anorexia nervosa (AN) and bulimia nervosa (BN), are prevalent disorders that carry substantial economic and social burden. The aim of the current study was to evaluate the modelled population cost-effectiveness of cognitive dissonance (CD), a school-based preventive intervention for EDs, in the Austral...
[Lampiran Journal Article] Age of onset of obesity and risk of type 2 diabetes.- [Lampiran Journal Article] Age of onset of obesity and risk of type 2 diabetes.[Lampiran Journal Article] Age of onset of obesity and risk of type 2 diabetes.[Lampiran Journal Article] Age of onset of obesity and risk of type 2 diabetes.[Lampiran Journal Article] Age o...
Background
Few trials have compared psychosocial therapies for people with bipolar affective disorder, and conventional meta-analyses provided limited comparisons between therapies.AimsTo combine evidence for the efficacy of psychosocial interventions used as adjunctive treatment of bipolar disorder in adults, using network meta-analysis (NMA).Meth...
Objective:
To systematically review and quantify the effectiveness of Eating Disorder (ED) prevention interventions.
Methods:
Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsychInfo, EMBASE, and Scopus) were searched for published randomized controlled trials of ED prevention interventions from 2009 to 2015. Tr...
Trans-fatty acids (TFAs) intake has been consistently associated with a higher risk of coronary heart disease (CHD) mortality. We provided an updated assessment of TFA intake in Australian adults in 2010 and conducted modeling to estimate CHD mortality attributable to TFA intake. Data of the 2011–2012 National Nutrition and Physical Activity Survey...
Background:
Eating Disorders (EDs) including Anorexia Nervosa (AN) and Bulimia Nervosa (BN) are prevalent and associated with substantial economic and social burden. The goal of this study is to evaluate the population cost-effectiveness of cognitive dissonance, a school-based selective intervention designed to prevent EDs.
Method:
A population-ba...
Chronic disease models can be used to assess the public health impact of secular changes in disease incidence, improved treatments, and starting or changing prevention and screening programs, among others. Age and time are crucial dimensions of disease models. Many approaches to chronic disease modeling exist, including analytical models, life-tabl...
OBJECTIVE: To compare a simple measure - age of onset of obesity - to an obese-years construct (a product of duration and magnitude of obesity) as risk factors for type 2 diabetes.
METHOD: Participants from the Framingham Heart Study who were not obese and did not have diabetes at baseline were included (n=4,320). The Akaike Information Criterion...
Background
: Norway has achieved a noteworthy reduction in smoking prevalence over the past forty years. In 2015, 13% of Norwegians aged 13–74 smoked daily and a further 9% smoked occasionally. One of the objectives of the Norwegian 2013–16 national strategy for tobacco control is to achieve a reduction in the daily smoking prevalence to < 10% by 2...
Aims:
School-based psychological interventions encompass: universal interventions targeting youth in the general population; and indicated interventions targeting youth with subthreshold depression. This study aimed to: (1) examine the population cost-effectiveness of delivering universal and indicated prevention interventions to youth in the popu...
Background
Eating disorders (EDs) are serious mental disorders which have significant physical and psychological impacts. The aim of this study is to determine whether ED prevention programs are effective across the age spectrum.
Method
Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsychInfo, EMBASE, and
Scopus) w...
The childhood obesity epidemic continues in the U.S., and fiscal crises are leading policymakers to ask not only whether an intervention works but also whether it offers value for money. However, cost-effectiveness analyses have been limited. This paper discusses methods and outcomes of four childhood obesity interventions: (1) sugar-sweetened beve...
This research letter reports the simulation comparison of two new methods of meta-analysis that solve the problems associated with the random effects model and discusses the advantages of replacing the latter with the newer methods in terms of estimator performance.
Objective
To quantify the burden of maternal and neonatal conditions in low- and middle-income countries (LMICs) that could be averted by full access to quality first-level obstetric surgical procedures.DesignBurden of disease and epidemiological modelling.SettingLMICs from all global regions.PopulationThe entire population in 2010.Methods
We inclu...
Rosiglitazone has previously been widely used to treat patients with type 2 diabetes mellitus, but its safety in terms of cardiovascular morbidity and mortality had been called into question. Recently, there have been doubts raised about the meta-analytic evidence with the regulatory authorities relaxing its restrictions. We hypothesized that the o...
Previous studies exploring the association between obesity and hypertension generally used a single baseline measurement of obesity. The effect of accumulating excess adiposity over time on the risk of hypertension is uncertain. This study aimed to examine the relationship between duration of obesity and incident hypertension using the Framingham H...
To quantify the burden of digestive diseases avertable by surgical care at first-level hospitals in low- and middle-income countries (LMICs).
We examined 4 digestive diseases from the Global Burden of Disease (GBD) 2010 Study: Appendicitis, intestinal obstruction, inguinal and femoral hernia, and gallbladder and bile duct disease. Using demographic...
Objective To quantify the burden of selected congenital anomalies in low and middle-income countries (LMICs) that could be reduced should surgical programmes cover the entire population with access to quality care.
Design Burden of disease and epidemiological modelling.
Setting LMICs from all global regions.
Population All prevalent cases of select...
Background
Alcohol is a major preventable cause of injury, disability and death in young people. Large numbers of young people with alcohol-related injuries and medical conditions present to hospital emergency departments (EDs). Access to brief, efficacious, accessible and cost effective treatment is an international health priority within this age...
Background:
Injuries accounted for 11 % of the global burden of disease in 2010. This study aimed to quantify the burden of injury in low- and middle-income countries (LMICs) that could be averted if basic surgical services were made available and accessible to the entire population.
Methods:
We examined all causes of injury from the Global Burd...
Objective
To demonstrate why meta-analytic methods need modification before they can be used to aggregate rates or effect sizes in outcomes research, under the constraint of no common underlying effect or rate.
Methods
Studies are presented that require different types of risk adjustment. First, we demonstrate using rates that external risk adjust...
The overdispersion in macroparasite infection intensity among host populations is commonly simulated using a constant negative binomial aggregation parameter. We describe an alternative to utilising the negative binomial approach and demonstrate important disparities in intervention efficacy projections that can come about from opting for pattern-f...
To estimate the global burden of low back pain (LBP).
LBP was defined as pain in the area on the posterior aspect of the body from the lower margin of the twelfth ribs to the lower glutaeal folds with or without pain referred into one or both lower limbs that lasts for at least one day. Systematic reviews were performed of the prevalence, incidence...
To estimate the global burden of neck pain.
Neck pain was defined as pain in the neck with or without pain referred into one or both upper limbs that lasts for at least 1 day. Systematic reviews were performed of the prevalence, incidence, remission, duration and mortality risk of neck pain. Four levels of severity were identified for neck pain wit...
Objective:
To estimate the percentage of Australians with a mental disorder who received treatment for that disorder each year between 2006-07 and 2009-10.
Methods:
We used: (1) epidemiological survey data to estimate the number of Australians with a mental disorder in any year; (2) a combination of administrative data on people receiving mental...
Meta-analysis is a method to obtain a weighted average of results from various studies. In addition to pooling effect sizes, meta-analysis can also be used to estimate disease frequencies, such as incidence and prevalence. In this article we present methods for the meta-analysis of prevalence. We discuss the logit and double arcsine transformations...
Background
An estimated 6% of global infant deaths are attributable to congenital anomalies, of which 92% occur in low-income and middle-income countries (LMICs). Some of the conditions can be treated by specialised surgical procedures that have been frequently provided through established vertical programmes. This study aims to quantify the burden...
Objective:
Smoking prevalence among Vietnamese men is among the highest in the world. Our aim was to provide estimates of tobacco attributable mortality to support tobacco control policies.
Method:
We used the Peto-Lopez method using lung cancer mortality to derive a Smoking Impact Ratio (SIR) as a marker of cumulative exposure to smoking. SIRs...
Epidemiological input parameters.
(DOCX)
To examine the cost-effectiveness of providing laparoscopic adjustable gastric banding (LAGB) surgery to all morbidly obese adults in the 2003 Australian population.
Analyzed costs and benefits associated with two intervention scenarios, one providing LAGB surgery to individuals with BMI >40 and another to individuals with BMI >35, with each compar...
Purposes:
(1) Determine the association of multiple cancers with smoking, focusing on cancers with an uncertain association; and (2) illustrate quantitative bias analysis as applied to registry data, to adjust for misclassification of smoking and residual confounding by alcohol and obesity.
Methods:
New Zealand 1981 and 1996 censuses, including...
Meta-analysis is now used in a wide range of disciplines, in particular epidemiology and evidence-based medicine, where the results of some meta-analyses have led to major changes in clinical practice and health care policies. Meta-analysis is applicable to collections of research that produce quantitative results, examine the same constructs and r...
Background Conducting a burden of road traffic injuries (RTIs) in developing countries is difficult due to the paucity and inconsistency of data.
Objectives This study aims to assess the burden of RTI in Thailand with a focus on long-term disability and examine the effect of replacing Global Burden of Disease (GBD) assumptions with data from Thaila...
Background:
Few studies have examined spontaneous remission from major depression. This study investigated the proportion of prevalent cases of untreated major depression that will remit without treatment in a year, and whether remission rates vary by disorder severity.
Method:
Wait-list controlled trials and observational cohort studies publish...
A unique challenge in meta-analysis of observational studies is bias adjustment. Two different approaches have been proposed for doing this – using summary scores versus component scores. The prevailing view on this matter is that summary quality scores are inaccurate because information from its components can cancel each other out.
A head-to-head...
Despite many decades of declining mortality rates in the Western world, cardiovascular disease remains the leading cause of death worldwide. In this research we evaluate the optimal mix of lifestyle, pharmaceutical and population-wide interventions for primary prevention of cardiovascular disease.
In a discrete time Markov model we simulate the isc...
Cost-effectiveness results with separate effects for men and women.
