Jacob E. Kuperstock's research while affiliated with University of Massachusetts Boston and other places

Publications (10)

Article
Background: Forehead feminization cranioplasty (FFC) risks entering the frontal sinus to achieve the desired contour. To date, no study has investigated long-term FFC complications. Objective: Determine if long-term sinus and headache symptoms worsen secondary to frontal sinus mucosal violation, measured by patient-reported outcomes. Methods: Singl...
Article
Importance: The risk of hematoma formation after rhytidectomy is gender associated and can lead to postoperative complications. The literature to help explain and elucidate the mechanism behind this gender-associated risk is poorly developed and requires further investigation. Objective: The objective of this study was to compare facial skin micro-...
Article
Purpose: Develop a model for quality improvement in tracheostomy care and decrease tracheostomy-related complications. Methods: This study was a prospective quality improvement project at an academic tertiary care hospital. A multidisciplinary team was assembled to create institutional guidelines for clinical care during the pre-operative, intra...
Article
Objective: Perceived gender identity is correctly assigned when a combination of physical and vocal attributes become congruent. Several voice feminization procedures have gained popularity, but current evidence of their impact on vocal feminization is limited to case series. This study establishes an ex vivo porcine phonatory model to evaluate th...
Article
Objective Otolaryngology residents face time‐management challenges between clinical duties and self‐directed learning. Mobile devices provide a new medium for education that could aid with educational efficiency. The objective of this study was to investigate whether spaced repetition mobile app use of an otolaryngology question bank was associated...
Article
Objective: Gender dysphoria is estimated to occur in over 1 million people in the United States. With decreasing stigma regarding the transgender population, it is likely more patients will seek medical and surgical gender transition as parts of their treatment. However, otolaryngologists may lack training in gender-confirming surgery. This study...
Article
Full-text available
Background/objective: The etiology and risk factors for angioedema remain poorly understood with causative triggers often going undiagnosed despite repeated reactions. The purpose of this study was to determine the relationship between inhalant allergen sensitization and angioedema. Methods: A retrospective review of patients who had in vitro in...
Article
Background: The relationship between allergic sensitization and radiographic sinus inflammation remains unclear. Objectives: To determine whether specific allergen sensitization is correlated with sinonasal radiographic opacification. Methods: Patients with chronic sinonasal symptoms were selected and included if they had allergy testing and a...
Article
Background: The purpose of this study was to determine if total serum immunoglobulin E (IgE) could predict monosensitization compared to polysensitization in patients with allergic rhinitis (AR). Methods: This was a retrospective study of a cohort of 1073 patients who underwent allergy testing. Differences in total IgE level between unsensitized...
Article
Full-text available
IgE-mediated allergy plays a well-established role in both nasal and pulmonary diseases due to the common epithelium and shared mediator responses of the upper and lower airways. This “unified airway” concept has also been described in other sites within the head and neck that contain similar respiratory mucosa: the middle ear and the larynx. This...

Citations

... This is important because the porcine larynx is a frequently used animal model for studying aspects of laryngeal function, which cannot be safely examined in human models. [10][11][12][13][14][15] The study of porcine vocal folds is limited by a lack of effective methods for eliciting porcine vocal fold oscillation in vivo. Many studies have built apparatuses to produce laryngeal oscillation in excised porcine larynges to overcome this challenge, [16][17][18][19] however, these strategies are limited by the fact that vocal fold oscillation cannot be observed in the setting of the vocal tract. ...
... There are mobile apps which can simulate surgical procedures and help in medical examination such as hearing and visual tests. 2,3 In 2017, there were 325,000 health apps available from 84,000 health app publishers, with about 78,000 apps added in the last year and by 2020 46% of clinicians plan to use medical apps. [4][5][6] In a study conducted in United Kingdom, 84% of the medical students said that smart devices were a useful addition to their education. ...
... Massenberg et al found that 30% of American ENT residents had exposure to transgender health, most commonly with facial and pitch surgeries such as cricothyroid approximation or endoscopic vocal cord shortening. 25 Exposure was similar in American OMS residencies, as identified in a national survey performed by Ludwig et al. 26 A survey of 38 program directors, which included not only dermatologists but also otolaryngologists, oculoplastic surgeons, and plastic surgeons, found that 47% of programs offer training in MIGAP procedures. 24 These are only preliminary studies in their respective specialties and may not capture the true residency experience and attitudes, as these studies were limited by low-response rates. ...
... Determining sensitivity to allergens is essential for the diagnosis and management of a patient with allergic diseases. Also, one study suggested that patients with AR or a history of angioedema should educate on the risks of allergen sensitization [15]. We initially hypothesized a positive association of chronic cough with sensitization to HDM and polysensitization, but our results indicated no association. ...
... In some cases, CRS was selfdiagnosed, and even with clinical examination, it is hard to differentiate between CRS and rhinitis. Thus, computed tomography (CT) scans are needed to confirm the diagnosis, which is not routinely performed in every patient [77]. Another reason why studies failed to find a correlation between CRS and dementia is that dementia is a disease manifested in old age, and CRS symptoms can be improved with aging due to the alterations in the immune system. ...
... Polysensitization is a highly prevalent clinical phenomenon (10). Recent meta-analyses and systematic reviews showed that SLIT with a single allergen is efficacious in both monosensitized and polysensitized patients with AR (11,12), while the effect of SLIT for AS is less complete. ...
... Accordingly, Nguyen et al. found that in atopic patients with OME, inflammation occurs in both the middle ear and the nasopharynx [36]. Hence, the unified airway concept presents a model that supports inflammation of the nasal cavity from AR resulting in inflammation of the ET and middle ear [37,38]. ...