Jacob D. Kattan’s research while affiliated with Icahn School of Medicine at Mount Sinai and other places

... The most common allergens in acute FPIES include cow's milk, soy, eggs, fish, and cereals [11,12]. However, with recent guidelines endorsing the early introduction of peanuts in early infancy, there has been an increase in peanut-induced FPIES [13]. ...

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A Review of Non-IgE Immune-Mediated Allergic Disorders of the Gastrointestinal Tract

... This age coincides with the development of dislike of a food, which generally happens around 6-7 years and persists into older age [55]. However, this area requires further study: Lee et al. [56] followed 44 patients (ages 2-13 years, median age 6.5 years, 4 children under age 5) up to 4 years post successful sustained unresponsiveness (SU) challenge to peanut and reported that all were still consuming peanut regularly. ...

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Oral Immunotherapy Should Play a Key Role in Preschool Food Allergy Management

... Researchers are exploring the association between the early introduction of complementary foods in infancy and the risk of developing food allergies, asthma, or atopic dermatitis during childhood. Meanwhile, a pediatric cohort has achieved success in baked egg and baked milk oral immunotherapy (S. Zhang, Kattan, et al. 2023). ...

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Traditional and Emerging Physical Processing Technologies: Applications and Challenges in Allergen Control of Animal and Plant Proteins

... The benefits of early introduction of peanut in the first year of life to the prevention of peanut allergy have been demonstrated by the Learning Early About Peanut Allergy (LEAP) study. 1 Since the early introduction of peanut, several publications have addressed an apparent increase in the amount of infants presenting with Food Protein Induced Enterocolitis Syndrome (FPIES) caused by the ingestion of peanut. [2][3][4][5][6][7] The hallmarks of this disease are severe vomiting within 1-4 h of ingestion of the culprit food and at least 3 minor criteria, as was published in an international consensus guideline 2017. 8 The incidence of FPIES to any food is reported to be 0.51%-0.7% in children (in the USA and Spain, respectively) 9,10 and for cow's milk 0.34% (in Israel). ...

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The prevalence of peanut‐triggered food protein‐induced enterocolitis syndrome in a prospective cohort of infants introducing peanut in the first year of life

... 27,28 Of the 17 studies in which both the number of participants and sex could be extracted, 65.4% of included children (n ¼ 1,112) were male. A wide range of age groups is represented in the studies, from infants 19,23,25,29,30 through to young adults 22,24e26,30e35 (Table E2). ...

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Barriers and Enablers of Dietary Reintroduction Following Negative Oral Food Challenge: A Scoping Review

... 34 Previous studies have shown that the SPT is a more accurate predictor of SA than ssIgE. 19,35 Our results support these findings for PSA. To the best of our knowledge, this is the first study to examine the significance of ssIgE in PSA. ...

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Natural history of sesame allergy in pediatric patients: Insight from a retrospective analysis

... These findings are particularly concerning considering the increasing incidence of cow's milk allergies in adults and especially children [20]. Despite the prevalence of "contaminated" chocolate samples, allergic reactions specifically due to chocolate are rarely reported, and only in a few cases have provided documentation supporting the IgE-mediated allergy of a patient (via an oral challenge) or the chemical analysis of a sample consumed [21]. In this study, we aimed to investigate whether "vegan" chocolate (VEC) was contaminated by milk proteins, allowing us to confirm whether such proteins were the cause of the reported clinical reaction in a boy. ...

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Unexpected Cow’s Milk Proteins in a “Vegan” Easter Egg as a Cause of Anaphylaxis

... On the other hand, cashew is not typically used in the Greek diet; ready-to-eat sauces, prepacked, and restaurant meals are the primary cause of accidental ingestion, the avoidance of which does not negatively affect the patient's overall health. Almond, although seldomly causes severe allergic reactions [27], is widely used in the Greek diet. Regarding walnut allergy, many Greek patients report symptoms in the context of LTP syndrome, where traces usually do not cause reactions [28]. ...

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Impact of Presumed Tree Nut and Peanut Allergy on Quality of Life at Different Ages

... Furthermore, the matrix effect in the presence of other food constituents plays a crucial role during heat treatment. For instance, CM allergenicity is likely to change in muffins and other baked milk products, suggesting that most allergens are destroyed during baking (Nowak-Węgrzyn et al., 2018;Sopo et al., 2016). Thus, the thermal stability and lability of allergenic proteins are a complex puzzle, even though they offer a great option for reducing CMA. ...

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Cow milk allergy: Its clinical aspects, mechanisms, and innovative mitigation strategies beyond enzymatic hydrolysis

... ( shellfish-induced food allergy is a food safety issue that urgently requires more research. (Kattan, 2016) Oysters are a common type of shellfish and are widely consumed as a major ingredient in a variety of foods worldwide. (Liu, Ma, Liu, & Zeng, 2023) However, the proportion of food allergy caused by oysters was corresponding to the amount consumed. ...

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Identification and analysis of immunological activity of two isoforms of tropomyosin in Alectryonella plicatula