JL Levy’s scientific contributions

... Although the wrinkles were improved transitory at months 1 and 3, the 6 and 12 months follow-up photographs revealed no improvement, evaluated by the volunteers themselves, by the physicians or by uninvolved, blinded interpreters (Fig. 1). As some individuals showed good clinical responses [21] and some investigations reported histological changes222324, a second study was initiated. In this study, the efficacy of multiple passes of Er:YAG thermal laser pulses at fluences below the ablation threshold was evaluated by clinical means, by histology and immunohistochemistry, by optical coherence tomography (OCT) and by in vitro/in vivo temperature measurements. ...

Reference:

Minimally invasive skin rejuvenation with Erbium: YAG laser used in thermal mode