J.H. Choi's research while affiliated with Pusan National University Yangsan Hospital and other places
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Publications (946)
Continuum robots have seen increased utilization in various fields such as aerospace, rescue operations, human interaction, and especially medicine. More specifically, in medicine, continuum robots have enabled minimally invasive surgeries and faster patient recovery time. However, the design of continuum robots needs to be improved, especially by...
Aims
Despite the well-established clinical benefits and strong recommendations in clinical guidelines, adherence to guideline-directed medical therapy (GDMT) is known to be insufficient. We investigated the adherence to GDMT and its impact on the 3-year clinical outcomes in patients with acute myocardial infarction (AMI).
Methods and results
Sourc...
Background
The data regarding long-term clinical outcomes according to statin intensity in elderly patients who have undergone percutaneous coronary intervention (PCI) for acute myocardial infarction (MI) is unclear.
Purpose
We aimed to investigate the long-term clinical benefit of high intensity statin versus moderate to low intensity statin in e...
Background/Introduction
High thrombotic risk (HTR) features are associated with higher ischemic rate, which may be mitigated by potent antiplatelet therapy. However, concomitant high bleeding risk (HBR) may be present, making it unclear whether the intensity of antiplatelet therapy should be prioritized.
Purpose
This study investigated the prognos...
Developable mechanisms are a relatively new class of mechanisms where a kinematic mechanism is integrated into a surface to make a conforming mechanism that can perform different tasks or functions. This article explores the integration of expanding segments into continuum robots utilizing developable mechanisms. A 4-bar planar mechanism was integr...
The acute compartment syndrome refers to an increase in pressure in a limited space within the body. This is an orthopedic emergency that requires prompt and accurate diagnosis, and objective indicators such as compartment pressure measurement are more important than the subjective judgment of the doctor. This study presents a motorized hand- held...
The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment designed for the search for sterile neutrinos. The experiment is currently at the stage of the second phase named JSNS$^{2}$-II with two detectors at near and far locations from the neutrino source. One of the key components of the experiment is an...
JSNS$^2$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment which searches for sterile neutrinos via the observation of $\bar{\nu}_{\mu} \to \bar{\nu}_{e}$ appearance oscillations using muon decay-at-rest neutrinos. The data taking of JSNS$^2$ have been performed from 2021. In this manuscript, a study of the accid...
A mini basket type mapping catheter consists of thin film flexible sensors and is applied in the medical field to measure the electrocardiography (ECG) signals in order to localize and quantize the physiological condition/status of heart. The flexible nature of the thin film changes the configuration with respect to the contact boundary conditions...
The thin film flexible sensor has applications in the medical field in measuring the electro cardiography (ECG) signals to localize and quantize the physiological condition/status of heart. Owing to the flexible nature of the thin film, its configuration changes with respect to the contact boundary condition when it comes in contact with the target...
Wire actuation in tendon-driven continuum robots enables the transmission of force from a distance, but it is understood that tension control problems can arise when a pulley is used to actuate two cables in a push-pull mode. This paper analyzes the relationship between angle of rotation, pressure, as well as variables of a single continuum unit in...
Objectives
Mortality following percutaneous coronary intervention (PCI) is a key quality measurement in clinical practice. This study investigated the 10-year trends of mortality following PCI in an unselected nationwide cohort.
Design
Retrospective cohort study.
Setting
A nationwide study in South Korea.
Participants
PCI claim data from 2006 to...
Background
Sex-specific survival following percutaneous coronary intervention (PCI) varies among studies. This might be clarified using relative survival, which adjusts observed survival in relation to that seen in sex- and age-matched general population. We investigated sex-specific relative survival after PCI.
Methods
A total of 48,783 patients...
Total unit number, unit length, and maximum bending angle of units are major design parameters in a discrete continuum robot. In this paper, a discrete continuum robot design methodology is suggested to determine the major design parameters for the transoral robotic surgery using a genetic algorithm (GA) based parameter optimization. If the transor...
We report the measured production rates of unstable isotopes Li9 and He8 produced by cosmic muon spallation on C12 using two identical detectors of the RENO experiment. Their β decays accompanied by a neutron make a significant contribution to backgrounds of reactor antineutrino events in precise determination of the smallest neutrino mixing angle....
We present a nearly reactor model independent search for sterile neutrino oscillation using 2 509 days of RENO near detector data and 180 days of NEOS data. The reactor related systematic uncertainties are significantly suppressed as both detectors are located at the same reactor complex of Hanbit Nuclear Power Plant. The search is performed by ele...
We report the measured production rates of unstable isotopes 9Li and 8He produced by cosmic muon spallation on 12C using two identical detectors of the RENO experiment. Their beta-decays accompanied by a neutron make a significant contribution to backgrounds of reactor antineutrino events in precise determination of the smallest neutrino mixing ang...
JSNS $$^2$$ 2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that is searching for sterile neutrinos via the observation of $${\bar{\nu }}_{\mu } \rightarrow {\bar{\nu }}_{e}$$ ν ¯ μ → ν ¯ e appearance oscillations using muon decay-at-rest neutrinos. Before dedicated data taking in the first-half of 2021, we p...
In percutaneous intervention for treatment of coronary plaques, guidewire navigation is a primary procedure for stent delivery. Steering a flexible guidewire within coronary arteries requires considerable training, and the non-linearity between the control operation and the movement of the guidewire makes precise manipulation difficult. Here, we in...
The RENO experiment reports measured flux and energy spectrum of reactor electron antineutrinos ν¯e from the six reactors at Hanbit Nuclear Power Plant. The measurements use 966 094 116 111ν¯e candidate events with a background fraction of 2.39% (5.13%), acquired in the near (far) detector, from August 2011 to March 2020. The inverse beta decay (IB...
BACKGROUND
In vitro generation of three-dimensional vessel network is crucial to investigate and possibly improve vascularization after implantation in vivo . This work has the purpose of engineering complex tissue regeneration of a vascular network including multiple cell-type, an extracellular matrix, and perfusability for clinical application....
JSNS$^2$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) is an experiment that is searching for sterile neutrinos via the observation of $\bar{\nu}_{\mu} \to \bar{\nu}_{e}$ appearance oscillations using muon decay-at-rest neutrinos. Before dedicate data taking in the first-half of 2021, we performed a commissioning run for 10 d...
In percutaneous intervention for treatment of coronary plaques, guidewire navigation is a primary procedure for stent delivery. Steering a flexible guidewire within coronary arteries requires considerable training, and the non-linearity between the control operation and the movement of the guidewire makes precise manipulation difficult. Here, we in...
Conventional vascular intervention procedures present issues including X-ray exposure during operation, and an experience-dependent success rate and clinical outcome. This paper presents a novel robotic system using modularized bi-motional roller cartridge assemblies for robotic vascular interventions, specifically percutaneous coronary interventio...
The JSNS2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for oscillations involving a sterile neutrino in the eV2 mass-splitting range. The experiment will search for the appearance of electron antineutrinos oscillated from muon antineutrinos. The electron antineutrinos are detected via the inverse be...
Skeletal muscle mass deficiency and quality degradation constitute sarcopenia for elderly people. Sarcopenia can result in musculoskeletal damage and accompany various metabolic problems, which make early sarcopenia diagnosis important. Various modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), have been developed fo...
In this study, to improve the prediction of pressure ulcer spots, we have developed super-resolution (SR) techniques to reconstruct a high-resolution (HR) pressure image from a low-resolution (LR) body pressure image to overcome the limitations of sensor resolution. We implemented a super-resolution generative adversarial network (SRGAN) to reconst...
The JSNS^2 (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for sterile neutrino oscillations in the eV mass range. A 1 MW beam of 3 GeV protons incident on a spallation neutron target produces an intense and pulsed neutrino beam from muon decay at rest. The JSNS^2 detector is located at 24 m away from...
The JSNS2 experiment aims to search for sterile neutrino oscillations using a neutrino beam from muon decays at rest. The JSNS2 detector contains 17 tons of 0.1% gadolinium (Gd) loaded liquid scintillator (LS) as a neutrino target. Detector construction was completed in the spring of 2020. A slow control and monitoring system (SCMS) was implemented...
Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms for medical diagnosis and prediction. Discrimination accuracy of AI algorithms is often evaluated with the Dice similarity coef...
This article describes the goal and expected sensitivity of the JSNS$^2$-II experiment at J-PARC Materials and Life Science Experimental Facility (MLF). The JSNS$^2$-II experiment is the second phase of the JSNS$^2$ experiment (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) with two detectors which are located in 24 m (an exist...
Artificial intelligence (AI) will likely affect various fields of medicine. This article aims to explain the fundamental principles of clinical validation, device approval, and insurance coverage decisions of AI algorithms for medical diagnosis and prediction. Discrimination accuracy of AI algorithms is often evaluated with the Dice similarity coef...
We report a search result for a light sterile neutrino oscillation with roughly 2200 live days of data in the RENO experiment. The search is performed by electron antineutrino (ν¯e) disappearance taking place between six 2.8 GWth reactors and two identical detectors located at 294 m (near) and 1383 m (far) from the center of the reactor array. A sp...
We present a model independent search for sterile neutrino oscillation using 2\,508.9\,days of RENO near detector data and a NEOS published result. The reactor related systematic uncertainties are significantly suppressed as both detectors are located at the same reactor complex of Hanbit Nuclear Power Plant. The search is performed by electron ant...
Background
Non-adherence to angiotensin receptor blockers (ARB) or statin is one of major reasons of insufficient treatment for patients with hyperlipidemia and hypertension. We investigated whether fixed-dose combination (FDC) of ARB and statin improved adherence compared to traditional free combination (FC).
Methods
In this retrospective nationw...
Background
The clinical impact of discontinuation of aspirin within 24 months after PCI for high risk patients who are receiving prolonged dual antiplatelet therapy (DAPT) is not known. We investigated the long-term outcomes prolonged DAPT among high risk patients after second-generation drug-eluting stent (DES) implantation.
Methods and results
O...
Background
The comparative gender-specific outcome after PCI in real-world practice is limited. We investigated the gender difference in the 5-year outcome after percutaneous coronary intervention (PCI).
Methods
A retrospective study. nationwide PCI registry. All PCI performed in Korea in year 2011 (N=48,783). Outcomes adjusted with age and propen...
Objective
In percutaneous coronary intervention, drug-eluting stent (DES) showed better clinical outcome compared to bare-metal stent (BMS) but mostly with different DAPT durations. This study investigated the clinical superiority of DES over BMS with regard to the medication adherence to dual antiplatelet therapy (DAPT).
Methods
We retrospectivel...
The RENO experiment reports measured flux and energy spectrum of reactor electron antineutrinos\,($\overline{\nu}_e$) from the six reactors at Hanbit Nuclear Power Plant. The measurements use 966\,094\,(116\,111)\,$\overline{\nu}_e$ candidate events with a background fraction of 2.39\%\,(5.13\%), acquired in the near\,(far) detector, from August 20...
This paper proposes a catheter robot system for electrophysiological catheters. The robot mechanism for controlling the catheter and the control methods of the catheter tip position will be suggested. The robot system consists of a front module and a handle control module. The front module is a dual-gripper mechanism for inserting and rotating the...
Sarcopenia is defined as muscle mass and strength loss with aging. As places, such as South Korea, Japan, and Europe have entered an aged society, sarcopenia is attracting global attention with elderly health. However, only few developed devices can quantify sarcopenia diagnosis modalities. Thus, the authors developed a sarcopenia detection system...
We report a search result for a light sterile neutrino oscillation with roughly 2200 live days of data in the RENO experiment. The search is performed by electron antineutrino ($\overline{\nu}_e$) disappearance taking place between six 2.8 GW$_{\text{th}}$ reactors and two identical detectors located at 294 m (near) and 1383 m (far) from the center...
The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for neutrino oscillations over a 24 m short baseline at J-PARC. The JSNS$^{2}$ inner detector is filled with 17 tons of gadolinium(Gd)-loaded liquid scintillator (LS) with an additional 31 tons of unloaded LS in the intermediate $\gamma$-ca...
The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment is designed to look for neutrino oscillations over a 24 m short baseline at J-PARC. The JSNS$^{2}$ inner detector is filled with 17 tons of gadolinium(Gd)-doped liquid scintillator (LS) with an additional 31 tons of un-doped LS in the optically separated...
The JSNS$^{2}$ (J-PARC Sterile Neutrino Search at J-PARC Spallation Neutron Source) experiment aims to search for neutrino oscillations over a 24\,m short baseline at J-PARC. The JSNS$^{2}$ inner detector is filled with 17 tons of gadolinium-loaded liquid scintillator (LS) and both the intermediate $\gamma$-catcher and the optically separated outer...
C. D. Shin Zohaib Atif G. Bak- [...]
I. Yu
The Reactor Experiment for Neutrino Oscillation (RENO) experiment has been taking data using two identical liquid scintillator detectors since August 2011. The experiment has observed the disappearance of reactor neutrinos in their interactions with free protons, followed by neutron capture on hydrogen (n-H). Based on 1500 live days of data taken w...
This paper introduces a newly developed robotic gait training system for lower-limb rehabilitation of stroke patients. The system (Cyborg-Trainer L; Cyborg-Lab Co., Korea) provides a stair-climbing mode in addition to the conventional level-walking mode by leveraging a unique exoskeleton structure with separately operable foot plates. Unlike conven...
In this paper we present a new robotic device for performing a percutaneous needle biopsy. The device is designed to perform introducer insertion and tissue sampling in organs of interest, such as the lung and liver. It is designed to have smaller parts and better performance than the previous models, and includes light-weight, sensor-based initial...
Background:
Endoscopes are widely used for visualizing the respiratory tract, urinary tract, uterus, and gastrointestinal tracts. Despite high demand, people in underdeveloped and developing countries cannot obtain proper access to endoscopy. Moreover, commercially available endoscopes are mostly nonarticulable as well as not actively controlled,...
BACKGROUND
Endoscopes are widely used for visualizing the respiratory tract, urinary tract, uterus, and gastrointestinal tracts. Despite high demand, people in underdeveloped and developing countries cannot obtain proper access to endoscopy. Moreover, commercially available endoscopes are mostly non-articulable as well as not actively controlled, l...
To reduce the radiation exposure of personnel during an interventional procedure for arrhythmia, a robot has been developed and implemented herein for use in interventional procedures. Studies on the control of an electrophysiology catheter by robots are being conducted. However, controlling a catheter using a robot has limited precision owing to e...
Background:
Selecting a topical treatment from among the numerous topical agents for external genital warts remains challenging without clear evidence.
Objectives:
To comparatively evaluate the efficacy and safety of topical agents for external genital warts via a network meta-analysis METHODS: We included all randomised, controlled trials that...
Background:
Robotic locomotion rehabilitation systems have been used for gait training in patients who have had a stroke. Most commercialized systems allow patients to perform simple exercises such as balancing or level walking, but an additional function such as stair-walk training is required to provide a wide range of recovery cycle rehabilitat...
Background
Data regarding clinical outcomes of biodegradable polymer drug-eluting stent (BP-DES) versus second-generation durable polymer drug-eluting stent (DP-DES) in patients undergoing percutaneous coronary intervention (PCI) are inconclusive.
Purpose
We aimed to perform a meta-analysis to investigate the clinical outcomes of BP-DES compared w...
Background
The true benefit of biodegradable polymer drug-eluting stent (BP-DES) over second-generation durable polymer drug-eluting stent (DP-DES) expected to be represented during late period of follow-up after percutaneous coronary intervention (PCI), but prior meta-analysis only evaluated short-term outcomes.
Purpose
We aimed to compare the lo...
More than half of post-operative complications can be prevented, and operation performances can be improved based on the feedback gathered from operations or notifications of the risks during operations in real time. However, existing surgical analysis methods are limited, because they involve time-consuming processes and subjective opinions. There...
The purpose of this study was to demonstrate self‐organizing in vitro multicellular tumor spheroid (MCTS) formation in a microfluidic system and to observe the behavior of MCTSs under controlled microenvironment. The employed microfluidic system was designed for simple and effective formation of MCTSs by generating nutrient and oxygen gradients. Th...
X-ray angiography, used in the evaluation of coronary artery disease, presents difficulties in the performance of quantitative coronary angiography analysis, by identifying major vessels. These difficulties are due to problems such as non-uniform illumination, low contrast ratio, and the presence of other tissues. Therefore, segmentation of the des...
This paper presents a new master manipulator applied to robotic systems for arrhythmia ablation. The manipulator is designed to implement the concept of two different master-slave teleoperation controls in the clinical application. One is the conventional control between the master and catheter-handle in the slave site and the other is catheter tip...
Background: Healthy skin is an important determinant of the quality of life and physical and mental well-being. The demand for dermatological information is increasing not only in patients with skin diseases, but also in the general population with normal/healthy skin. However, public perception and behavior with regard to skin health among Koreans...
Microcystic adnexal carcinoma (MAC) was first described in 1982 by Goldstein. Considered a rare malignant skin appendageal tumor, it is often underdiagnosed due to its clinical and histopathological resemblance to other cutaneous neoplasms. MAC is locally aggressive with infiltration of perineural spaces, subcutaneous tissue, skeletal muscles, and...
In this paper, we propose a new technique to recognize vessels in robot-assisted laparoscopic surgery images by using surgical instruments. The proposed method does not require additional hardware or parameter adjustment because it detects blood vessels by using only the color information of the image. The concept of a hessian matrix is used in the...