J.-X. Zhu’s scientific contributions

To study the chemical constituents of Vernonia chunii of Hainan province, the constituents were separated and purified by column chromatography with macroporous adsorption resin Diaion HP-20, Sephadex LH-20, Toyopearl HW-40(C), MCI Gel CHP-20, RP-18 and normal phase silica gel. Their structures were identified on the basis of physiochemical properties and spectral methods ( 1H NMR 13C NMR distorsionless enharrrecment by polarization transfer (DEPT), 1H- 1H correlation speclroscopy ( 1H- 1H COSY), helernuclear single quantum correlation (HSQC), heternuclear multiple bond correlation (HMBC), ESI-MS, IR). Seven compounds were isolated and identified as; 3, 2′-bis (3,4-dihydroxyphenyl)-5, 3′-dihydroxy-6,7-combine dihydropyran-3,4- dihydro-benzopyrone( I ), I, 3-di-o-caffeoylquinicacid (II), 1, 5-di-o-caffeoylquinicacid (III), l-(3,4-dimethoxyphenyl)-2,3-dimethanol-6,7- dimethoxy-l, 2, 3, 4-tetrahydronaphthalene(IV), Chlo-rogenic acid(V), Caffeic acid(VI)and Ferulic acid(VII). Compound I is a new compound, the other componuds were isolated from this plant for the first time.

To study the chemical constituents of Mimosa pudica of Hainan province, the constituents were separated and purified by column chromatography with macroporous adsorption resin Diaion HP-20, Sephadex LH-20, Toyopearl HW-40, MCI Gel CHP-20, RP-18 and normal phase silica gel. Their structures were identified on the basis of physiochemical properties and spectral methods( 1H NMR, 13C NMR,H- 1H COSY, het-eronuelear xingle quantum correlation ( HSQC ), heterronuclear multiple bond correlation ( HMBC ), ESI-MS, IR). Two compounds were isolated and identified: 5,7,3′,4′- teteahydroxy-6-C-[β-.D-apiose-(1→4) ]-β-D-glucopyranosyl flavone(I) and 5, 7,4′-trihydroxyl-8-C-β-Z)-grucopyranosyl flavone(II). Compound I is a new c-glycosylflavones, Componud H was isolated from this plant for the first time.