J S Volek’s research while affiliated with University of Connecticut and other places

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Publications (121)


Adaptations of achilles and patella tendons in chronically resistance-trained and moderately active men.
  • Conference Paper

July 2015

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25 Reads

Comstock BA

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Table 2 . Change in resting metabolic rate and macronutrients oxidation
Table 4 . Body mass and body composition by group and time
Effect of resistance training on resting metabolic rate and its estimation by a dual-energy X-ray absorptiometry metabolic map
  • Article
  • Full-text available

October 2014

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1,714 Reads

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49 Citations

European Journal of Clinical Nutrition

Background/objectives: Fat-free mass (FFM) is the major predictor of resting metabolic rate (RMR). As protein supplementation during resistance training may augment gains in FFM, we investigated the effects of resistance training combined with protein supplementation on RMR and whether RMR responses could be estimated by a dual-energy X-ray absorptiometry (DXA) metabolic map. Subjects/methods: Healthy adults completed a whole-body periodized resistance training program consisting of 96 workouts (~9 months). Participants were randomly assigned to supplement with whey protein (whey; n=18), soy protein (soy; n=21) or carbohydrate (carb; n=22). RMR was measured using indirect calorimetry (RMR(IC)) and estimated by DXA metabolic mapping (RMR(MM)) pretraining and posttraining. Results: RMR(IC) increased from pretraining to posttraining in the whole cohort (1653±302 to 1726±291 kcal/day, P=0.001) without differences between the groups. Delta RMR(IC) and RMR(MM) (73±158 vs 52±41 kcal/day were not significantly different by t-test (P=0.303), although they were not significantly correlated (r=0.081; P=0.535). Stepwise regression identified 43% of the shared variance in delta RMR(IC) using total serum thyroxine, RMR(IC) and FFM at baseline (P=0.009). Conclusions: These results indicate that 9 months of resistance training significantly increased RMR ~5% on average, but there was wide variability between individuals, which can be partially accounted for by changes in FFM and thyroid hormones.

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68. Reduction of hair glucocorticoid levels in an animal model of post-traumatic stress disorder (PTSD)

September 2013

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10 Reads

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3 Citations

Brain Behavior and Immunity

PTSD results from exposure to a horrific, life-threatening experience. We have developed an animal model of PTSD which involves intense fear-provoking experiences (predator exposure) occurring in conjunction with social instability. Rats exposed to this psychosocial stress (PSS) regimen exhibit changes in physiology and behavior that are comparable to symptoms of people with PTSD (Stress, 11:259–281, 2008). One clinical anomaly, the subject of much debate, is whether basal glucocorticoid (GC) levels are abnormally low in PTSD. There is inconsistent evidence of lower basal GC levels in PTSD, as well as in our animal model of PTSD (Zoladz and Diamond, Neurosci. & Biobehav. Rev., 2013; PNE, 2012). In the current work we addressed this by measuring corticosterone levels in serum, and in a novel approach, fur cortisol of rats exposed to PSS. Adult male rats were immobilized and exposed to a cat twice during a 31 day period of unstable housing followed by fur and basal blood sampling. Rats administered PSS exhibited reduced cortisol levels in fur (1.84 ± 0.22 vs. 3.08 ± 0.45 ng/dl; p < 0.05), but not in serum (54.6 ± 12.4 vs. 55.0 ± 16.5 ng/ml; p = 0.9). These findings replicate evidence of reduced hair cortisol in people with PTSD (Biol Psychiatry 72: 65–69, 2012), which may be a more reliable measure of baseline GCs than is found in serum in rats and traumatized people.







Citations (51)


... Only a limited number of studies have examined EEG signals during traditional forms of resistance exercise involving significant muscle mass. The finding that different resistance training protocols involving squat movements provide unique maps of motor related cortical potential indicates the importance of the acute program variables (intensity and volume) to physical development in individuals (Comstock et al., 2011). During bench press movements while recording EEG signals over a single electrode, Engchuan et al. (2017) observed a significant increase in beta and gamma amplitudes as compared to baseline conditions. ...

Reference:

The potential of fNIRS, EEG, and transcranial current stimulation to probe neural mechanisms of resistance training
EEG Measures of Cortical Activity with Different Types of Acute Resistance Exercise Workouts
  • Citing Article
  • March 2011

The Journal of Strength and Conditioning Research

... Feeding increases GCs, and GREs are found within the promoter region of the Per genes (83), providing a mechanism by which peripheral oscillators can be entrained by these hormones (26). Because the timing of GC release is altered by feeding and exercise (144), these two behaviors can have substantial impact on the circadian system. Disruptions to peripheral clock timing are associated with obesity and metabolic disease (302) and time-restricted feeding (TRF) and timed exercise can coordinate the timing of peripheral organ rhythmicity and improve metabolic health (72, 152,557). ...

Glucocorticoid Receptor Expression on Human B-Cells in Response to Acute Heavy Resistance Exercise
  • Citing Article
  • March 2011

The Journal of Strength and Conditioning Research

... Three previous studies (Ho 2009;Pomerleau et al. 1987;Scerbo et al. 2010) have explored the role of cortisol with respect to exercise and cigarette cravings, among nonabstaining smokers (Ho 2009;Pomerleau et al. 1987), and after a 3-h abstinence period (Scerbo et al. 2010). One of these reported higher cortisol levels post-exercise compared with a passive control, but the differences in cortisol concentration were not associated with changes in cigarette cravings (Scerbo et al. 2010). ...

Effects of Resistance Exercise on the HPA Axis Response to Psychological Stress During Short-Term Smoking Abstinence in Men
  • Citing Article
  • March 2011

The Journal of Strength and Conditioning Research

... Subsequently, other investigators examined performance benefits from sub-chronic (2 weeks) betaine supplementation in RE. The results of these studies provide equivocal evidence, with some reporting improvements in strength and power [12,13], and others reporting no improvements in these performance parameters [8,14,15]. Nevertheless, it has been suggested that betaine may have a potential ergogenic effect in RE protocols with high metabolic stress [2]. ...

The Influence of Betaine Supplementation on Work Performance and Endocrine Function in Men
  • Citing Article
  • March 2011

The Journal of Strength and Conditioning Research

... These reservations relate to the usually conventional and fragmentary assumptions made by the authors, which prevents them from drawing informative conclusions about the many aspects of the effects of these substances on the human organism [9,13,24,37,41,50]. Particularly questionable are: short time (usually 6-9 days) of administration of the supplements, differences in the recommended doses and combination with other substances, recruitment of competitors doing sports other than strength sports, and lack of discussion of the obtained results in view of the training loads applied, which may undoubtedly affect the former. ...

Testosterone concentrations in women: relationship to the trainability of neuromuscular performance
  • Citing Conference Paper
  • November 1998

... Lack of physical activity throughout a male's life is a determinant for loss of muscular mass. When males perform no physical activity, muscular loss begins at an earlier age, increases with age, and has a functional impact in the older population (Anderson & Kearney, 1982;Bottaro, Machado, Nogueira, Scales, & Veloso, 2007;Marx et al., 1998;Ringsberg, Gerdhem, Johansson, & Obrant, 1999;Tsourlou, Benik, Dipla, Zafeiridis, & Kellis, 2006). The evaluation of muscular mass and its relationship to the muscular performance items (handgrip test, 4 MSTs, and chair test) showed that all parameters in the male groups were related to muscle volume, which supports the premise that physical activity increases muscular performance (speed and strength). ...

The effects of a low-volume progressive resistance exercise program versus a high-volume periodized resistance exercise program on muscular performance in women
  • Citing Conference Paper
  • November 1998

... Muscle architecture has been found to be highly associated with SSC performance in movements such as sprinting and jumping performance (2,15,25). Previous research has observed that competitive sprinters with .100-m running times possessed longer FL and lower PEN in their gastrocnemius (GAS) and VL muscles (25). ...

Erratum: Lower-body muscle structure and its role in jump performance during squat, countermovement, and depth drop jumps (Journal of Strength and Conditioning Research (2010) 24 (722-729))
  • Citing Article
  • June 2010

... While some of these provide advice on portion size and nutrient needs relative to metabolic demands (Duffey and Popkin, 2011;Fern et al., 2015), the majority offers biased perspectives: typically exaggerating the need for protein in the diet, indicating success comes through the reduction of carbohydrate consumption (i.e. ketogenic diets), or misrepresenting the benefits of timerestricted dieting or intermittent fasting (Brown et al., 1983;Clark, 2019;Di Francesco et al., 2018;Escobar et al., 2015;Headland et al., 2016;Paoli et al., 2013;Phillips et al., 2015;Rynders et al., 2019;Shai et al., 2008;Tinsley and La Bounty, 2015;Volek and Westman, 2002;Westman et al., 2007). There is also indication among these recommendation for the use of dietary supplements, such as thermogenic agents (e.g. ...

Very-low-carbohydrate weight-loss diets revisited
  • Citing Article
  • November 2002

Cleveland Clinic Journal of Medicine

... As of this writing, 16 controlled trials have investigated the effects of a ketogenic diet on athletic performance (Table 1) [21,30,[34][35][36][37][38][39][40][41][42][43][44][45][46][47]. Of these studies, none exclusively involved females and most involved only males (11 trials); participants included either recreationally active adults (11 trials) or elite athletes (5 trials). ...

Endurance capacity and high-intensity exercise performance responses to a high-fat diet
  • Citing Article
  • December 2003

International Journal of Sport Nutrition

... From the 11 studies (5–7, 10, 17–20, 22, 23, 25) that assessed bone mainly in normal-weight boys and girls, 8 (5–7, 18–20, 23, 25) reported significant positive effects on BMD and BMC for total body or specific body sites (e.g., lumbar spine). Five of these studies(5,19,20,23,25) showed a significant increase in total body BMD ranging from 2.5% (after a 12-wk intervention with dairy and three 1-h resistance exercise sessions/wk) (20) to 13.4% (after a 1-y intervention) (23). Furthermore, the other 2 of these 5 studies with an 18-mo intervention (5) and a 2-y intervention (25) found changes of 9.6% and 10.4% in total body BMD, respectively, whereas 1 study with a 2-y intervention (19) found a 3.2% increase in BMD after adjusting for size. ...

Increasing fluid milk favorably affects bone mineral density responses to resistance training in adolescent boys
  • Citing Article
  • October 2003

Journal of the American Dietetic Association