J Kimber's research while affiliated with UNSW Sydney and other places

Publications (13)

Article
In Scotland, deaths in drug users are known to be higher than in the rest of the UK and most of Europe. Reducing drug-related deaths is currently a national priority for the Scottish Government. This study aimed to present a description of the life histories of a group of injecting drug users who have recently died, with a view to highlighting area...
Article
AIMS: To review the evidence on the effectiveness of harm reduction interventions involving the provision of sterile injecting equipment in the prevention of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) transmission among injecting drug users (IDUs). The interventions assessed were needle and syringe programmes (NSP), alternative...
Article
To examine survival and long term injecting cessation (LTC) in a cohort of drug users recruited in a primary care setting. Open cohort with a mean of 10.2 years (SD 6.8, range <1–25) follow-up. Data sources were primary care notes, participant interviews and linkage to the national mortality register. A large general practice surgery in Edinburgh...
Article
Background: Buprenorphine maintenance treatment has been evaluated in randomised controlled trials against placebo medication, and separately as an alternative to methadone for management of opioid dependence. Objectives: To evaluate buprenorphine maintenance compared to placebo and to methadone maintenance in the management of opioid dependence...
Article
The topic of drug consumption facilities or rooms (DCRs) was reviewed by Dolan, Kimber and others in Harm Reduction Digest 10, published in the September 2000 issue of DAR. As one of the first English language papers on the topic this paper has been cited extensively. Now, 3 years on, these authors and have brought together an international team of...
Article
Methadone maintenance was the first widely used form of opioid replacement therapy developed to treat heroin dependence, and it remains the best-researched treatment for this problem. Despite the widespread use of methadone in maintenance treatment for opioid dependence in many countries, it is a controversial treatment whose effectiveness has been...
Article
Buprenorphine has recently been reported to be an alternative to methadone and LAAM for maintenance treatment of opioid dependent individuals, differing results are reported concerning its relative effectiveness indicating the need for an integrative review. OBJECTIVES: To evaluate the effects of buprenorphine maintenance against placebo and methad...

Citations

... The study uses data that were collected as part of the Australian NEPOD. [9][10][11][12] Six clinical trials included in NEPOD that evaluated maintenance pharmacotherapies for the treatment of heroin dependence (methadone, buprenorphine, LAAM, and naltrexone after detoxification) collected SF-36 data. Details of the trials are being reported separately. ...
... MTD for OUD is listed as an essential medicine by the World Health Organization and is the MOUD option most consistently associated with reduced mortality and other beneficial outcomes. [25][26][27][28] BUP has demonstrated superiority compared to NTX in one randomized controlled trial and is also more consistently associated with reduced mortality and other beneficial outcomes. [28][29][30] However, it does appear these highly effective options are mostly avoided within PHPs due to concerns related to impairment. ...
... This practice was more common with younger Aboriginal people who inject drugs (Gray et al., 2001). Injecting in public spaces may reduce the likelihood of using safer injecting practices (Southgate et al., 2003). Common locations of injecting include homes, parks, public toilets and stairwells, with privacy playing an important factor (Coupland et al., 2005). ...
... Harm reduction (HR) interventions traditionally focused on adults who engage in "problem" drug use (Kimber et al. 2010). This approach misses people who engage in "recreational" drug use and do not fit this profile, for example, young festival attendees. ...
... In the early 1980s, Scotland experienced an epidemic of injection drug use (7) and of injection-related blood-borne viruses, notably human immunodeficiency virus (8), hepatitis B virus (9), and hepatitis C virus (10) infections. Scotland was quick to invest in blood-borne virus prevalence studies (11)(12)(13) and in capture-recapture estimation of its current IDUs (14,15), but incidence studies-whether of blood-borne viruses (16) or initiations to injecting (3)-were initially lacking. ...
... As compensation for their time and travel, participants were offered an AUD$40 food voucher [33]. All researchers completed a three-hour training session on administering the client survey and adhering to an interviewer safety protocol [34]. On average, surveys took 45 minutes to complete. ...
... [5,53] Because of their ability to prevent health and community costs, supervised injecting facilities now operate in 26 European cities, and an ongoing evaluation of a supervised injecting facility in Sydney, Australia, has recently reported substantial public health benefits. [54,55] After supervised injecting facilities were initiated, it was observed that the sustained contact with health care professionals enabled substantially higher uptake of treatment services. [53] Supervised injecting facilities are more than simply safer places to inject, and are most effective when offered as one part of a comprehensive intervention including primary medical care to treat minor infections before they require hospitalization and substantial investment in drug treatment to help addicts to become abstinent. ...
... There was an absence of active follow up and so any cessation of declared behavioural risks was not accounted for; the use of a short median follow up time, however, limits any resultant bias. Additional factors contributing to excess mortality, and common amongst this group, were not measured, including: high rates of smoking, high levels of alcohol consumption that is not acknowledged as problematic, low socioeconomic status, low quality of life, high rates of depression and co-morbidity, and poor diet (Copeland et al., 2012). It is also important to note that whilst our findings should inform management of older, active, opioid users, we are unable to make inferences about longer-term mortality outcomes for those who desist from use at a younger age, although this may not be the norm (Termorshuizen et al., 2005;Hser et al., 2004). ...
... Previous research also found a 6-fold higher odds of heroin overdose among participants who were commonly using healthcare services such as hospitals or emergency departments (Kimber et al., 2003). The variety of reasons for this use of services are likely to include daily drug injection, homelessness and unstable housing, sex work, and other informal income generation activities all of which combine to increase the risk of experiencing heroin overdose (Kimber et al., 2003). ...
... Another common pattern of combining opioids and methamphetamine is the use of methamphetamine while using methadone (13)(14)(15). Globally, methadone maintenance therapy (MMT) is a predominant form of medication for opioid use disorder and it has been shown to help reduce injecting drug use, syringe sharing, engaging in risky sexual behaviors, and overall, the chances of HIV acquisition (13,15,16). In Iran, opioids are among the most frequently used substances, but methamphetamine has gained popularity. ...