J Derka's research while affiliated with University of Veterinary and Pharmaceutical Sciences Brno and other places

Publications (6)

Article
Full-text available
Based on a survey of 36 inbred and 8 partially inbred chicken lines and outbred jungle fowl, and with 29 alloantisera generated in different laboratories, 13 7S Ig and 5 IgM allotypes were designated and a new system of nomenclature for chicken Ig polymorphisms was developed. The survey also revealed considerable genetic polymorphism in the structu...
Article
Comparison of two inbred chicken lines (Fx > 99.9%) revealed significant differences in shape of the red blood cells (RBC). The length-width index was lower for both sexes in IC-line (1.46) when compared to CB-line chickens (1.88). Phenotypic expression of this character in F1 hybrids and both backcross groups corresponded to the common manifestati...
Article
In the course of study of alloantigenic immunoglobulin polymorphisms in 10 inbred chicken lines we detected 7 IgG allotypic specificities and 3 IgM allotypes. All birds in a given line possessed a unique combination of several IgG alloantigenic specificities (forming the phenogroup) which is presumably controlled by one allele at the locus designat...
Article
Full-text available
Derka J.: Allotypes of Chicken Immunoglobulin G (IgG). Acta vet. Brno, 48,1979: 2S-33. Ten allotypic specificities of chicken IgG designated K4, KS, K6, K7, K8, K9, KI0, K20, K21 and K30 were detected with the alloantisera prepared. The proge­ nies of selected parent crossings were used for their genetic analysis which showed that each of the first...
Article
In the (CB X WB) x WB backcross generation of hybrids between inbred lines of chickens responding strongly (CB) or weakly (WB) to the dinitrophenol group conjugated to chicken gamma globulin (DNP CGG), an association between good production of anti DNP antibodies and the B1 allele at the major histocompatibility system of chickens was found. No inf...

Citations

... Although four chicken IgM allotypes, IgM1a, IgM1b, IgM1c, IgM1d and multiple chicken IgY allotypes have been demonstrated serologically, 33,34 no corresponding amino acid or DNA sequence information has been available to date. The polymorphisms reported here, show the presence of putative chicken immunoglobulin allotypes at the DNA level, although we cannot link them to the previously published allotypes. ...
... Further studies mapped the Ir-GAT locus within the region encoding the B-L antigens (Palmer and Nordskog, 1982). Similarly, quantitative differences in the antibody response of chickens to the hapten dinitrophenol (DNP) conjugated to chicken gamma-globulin, have been shown to be associated with differences at the B-complex (Balcarova et al.. 1974). ...