Isabelle Soerjomataram’s research while affiliated with International Agency for Research on Cancer and other places

... The Global Burden of Disease Study indicated a notable increase in pancreatic cancer cases and deaths from 1990 to 2017, especially in high-income areas [111]. In Southeast Asia, both the incidence and mortality of this type of cancer are increasing and are projected to significantly increase by 2050 [112]. The initiation of abnormally activated lipid metabolic reprogramming plays a key role in the development of PDAC, which can develop into a deadly malignant tumour with a high probability of recurrence and distant metastasis [69]. ...

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Unlocking the lipid code: SREBPs as key drivers in gastrointestinal tumour metabolism

... Breast cancer (BC), one of the leading causes of death for women worldwide, has drawn attention as a significant issue for women's health [1]. This tumor was the most prevalent neoplasm worldwide, surpassing lung cancer in frequency, according to data from the GLOBOCAN survey and 3.2 million new cases of BC and 1.1 million annual deaths from the disease are predicted by 2050 [2,3]. Thus, screening and preventative initiatives are the most effective means of reducing the incidence and mortality of BC [4]. ...

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Evaluation of miR-27a-5p and miR-449a as potential serum biomarkers for breast cancer: a combined bioinformatics and experimental study

... Literature shows high-income countries (HICs) having higher survival rates, in contrast to those reported by LMICs [7,8]. This is linked to system challenges such as limited resources for early detection, optimal cytoreductive surgery and drug treatment, surveillance in LMICs [9,10], and patient challenges such as delayed presentation [11]. Therefore, proactive strategies, including increased resource allocation and improved access to training, diagnostics, treatment and prevention, are essential to address OC challenges in LMICs [12,13]. ...

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Challenges and Opportunities in Ovarian Cancer Care: A Qualitative Study of Clinician Perspectives from 24 Low- and Middle-Income Countries

... Breast cancer (BC) is the most common type of cancer, commonly diagnosed in women, although it can occur in men [1]. It poses a significant health burden globally, with over 2 million new cases diagnosed in 2022 [2]. It is also one of the leading causes of death in women worldwide, despite its downward trend, particularly in developed countries. ...

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Impact of e-Health Interventions on Mental Health and Quality of Life in Breast Cancer Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

... These factors contributed to increased psychological stress and anxiety among oncology patients. This has been confirmed by numerous systematic reviews and meta-analyses conducted by Riera et al. (2021), Tegelia, Angelini and Astolfi (2022), and Shah et al. (2025) [27,28,29]. Studies have also shown that changes in active cancer treatment and restrictions on social contact were associated with a deterioration in patients' mental well-being. ...

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Demographic factors, cancer history, and stress coping strategies among colorectal cancer patients during the end of the COVID-19 pandemic – a cross-sectional association study

... Oropharyngeal squamous cell carcinoma (OPSCC) represents a significant global health burden, with an estimated annual incidence of 93,000 cases [1][2][3][4]. Around the year 2000, human papillomavirus (HPV) has been established as an etiological agent for OPSCC, with over 70% of cases in high-income regions such as North America and Europe now attributed to HPV infection [5][6][7]. However, epidemiologic data from China reveal a distinct landscape, with HPV-mediated OPSCC remaining comparatively rare, suggesting region-specific etiologic and environmental influences [8,9]. ...

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Prognostic analysis of inconsistent combinations of HPV and p16 in a Chinese/Asian oropharyngeal squamous cell carcinoma population

... Accumulating evidence attributes the declining PCa incidence in HICs to reduced reliance on PSA screening, alongside the integration of multiparametric magnetic resonance imaging into diagnostic protocols. Such advancements enable more precise identification of clinically significant PCa, thereby curbing overdiagnosis and unnecessary biopsies (32,49). Moreover, studies highlight the association between lower PCa-related DALYs and mortality rates in high SDI regions with superior quality in healthcare delivery, including early detection programs, prevention interventions, and optimized therapeutic management (50). ...

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The global, regional, and national prostate cancer burden and trends from 1990 to 2021, results from the global burden of disease study 2021

... Kanker payudara merupakan salah satu jenis kanker yang paling umum pada wanita di seluruh dunia, termasuk di Indonesia. Menurut laporan WHO dalam Morgan et al. (2024), kanker payudara menyumbang lebih dari 2,3 juta kasus baru setiap tahun. Tingginya angka kejadian ini menuntut pendekatan terapi yang holistik, yang tidak hanya berfokus pada pengobatan medis tetapi juga mencakup faktor psikososial seperti dukungan keluarga. ...

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HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN TERAPI PADA PASIEN KANKER PAYUDARA DI RSUD Dr. SOETOMO SURABAYA

... 8 For example, a 2024 systematic review and meta-analysis of all studies on alcohol use and female breast cancer showed that for consumption of less than one standard drink (10 g pure alcohol per day), the relative risk estimate for breast cancer was significantly elevated at 1·04 (95% CI 1·01-1·07) compared with the counterfactual scenario of not drinking. 9 Such information is important, together with absolute risk information, since many women consume alcohol at lower levels than men. 10 Consequently, relatively large proportions of alcohol-attributable cancer (14%) are caused by drinking fewer than two drinks a day globally; in absolute numbers, this amounts to more than 100 000 cases a year. 2 In the past two decades, alcohol producers have strongly opposed the introduction of mandatory cancer warning labels on alcohol beverage containers in various jurisdictions. 11 Such opposition has even resulted in the termination of research examining the use of cancer warning labels. ...

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Labels warning about alcohol-attributable cancer risks should be mandated urgently

... Additionally, this study looks at trends in leukemia cases, deaths, and the impact on quality of life, aiming to uncover inequalities and provide insights for designing better interventions. The findings of this study serve as an important extension and supplement to previous research on the leukemia burden (15,16) and also contribute to the development of leukemia response strategies tailored to different countries and regions. ...

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Global, regional, and national burden of leukemia, 1990–2021: a systematic analysis of the global burden of disease in 2021