Igor Lemus’s research while affiliated with University of Santiago, Chile and other places

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Publications (11)


Hypoglycaemic activity of four plants used in Chilean popular medicine
  • Article

March 1999

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345 Reads

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112 Citations

Phytotherapy Research

I Lemus

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E Delvillar

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G Knop

The hypoglycaemic activity of a 20% dried leaf infusion of Bauhinia candicans Benth. (Leguminosae), Galega officinalis L. (Leguminosae), Morus alba L. (Moraceae) and Rubus ulmifolius Schott. (Rosaceae), used for diabetes in Chilean popular medicine, was evaluated in alloxan and streptozotocin induced hyperglycaemic rats. In normal rats the different infusions did not modify significantly the glycaemia in the period studied, but in diabetic rats different results were observed, depending on the diabetogenic drug used. B. candicans and R. ulmifolius infusions elicited remarkable hypoglycaemic effects in both experimental models. B. candicans presented a greater decrease of glycaemia in alloxan diabetic rats (39%) and R. ulmifolius showed a similar activity in both alloxan and streptozotocin diabetic rats (28% and 29%). Activity-guided fractionation of R. ulmifolius showed that petroleum ether extracts elicited a marked hypoglycaemic effect (35%) in the streptozotocin induced model.


Biological and chemical study of paico (Chenopodium chilense, Chenopodiaceae)

August 1997

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180 Reads

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15 Citations

Journal of Ethnopharmacology

The methanolic extract of the aerial portion of Chenopodium chilense Schrad., used in Chilean traditional medicine as a remedy for stomach-ache, has been found to exert the major spasmolytic activity in acetylcholine contracted rat ileum. This extract, with a complex flavonoid patterns on thin layer chromatography (TLC) analysis, is practically non-toxic both for rats and brine shrimp Artemia salina in acute toxicity test.




Acción antimicótica de extractos de Allium sativum
  • Article
  • Full-text available

January 1987

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99 Reads

Boletín Micológico

Se realizó un estudio fitomicrobiológico con extractos de Allium sativum (ajo). se identificó en el extracto el principio activo alicina. Se estudió su acción antimicótica frente a varias cepas de Aspergillus fumigatus, Candida albicans y diversos dermatofitos. También se comparó la actividad antimicótica de estos extractos con diversos fármacos antimicóticos de uso clínico.

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Citations (5)


... Of course, it has been reported that only aloe vera gel with high water content improves wound healing and increases new epithelialization, due to its ability to keep the wound moist. 33,34 However, plasma jet-treated aloe vera at a distance of 20 mm may be used as a basis in optimizing healing efficacy. Varying plasma jet treatment times may turn out to be the best treatment model. ...

Reference:

Plasma jet treated Lidah Buaya (Aloe vera) slice influences proliferative phase of wound healing
Humectant properties of Aloe perryi
  • Citing Article
  • January 1985

... Methylcinnamate and methyl-p-coumarate play important roles in plant-insect interactions and are widely distributed throughout the plant kingdom. They have been identified in both aerial and underground tissues from monocots and dicots as well as from ferns (Konda and Kawazu, 1979;Schaefers and Herrmann, 1982;Williams and Whitten, 1983;Hooper et al., 1984;Bandara et al., 1988;Cambie et al., 1990;Garcia et al., 1990;Seifert and Unger, 1994;Hiraga et al., 1996;Daayf et al., 1997a;Odell et al., 1999;Wu et al., 1999;Dias et al., 2003;Bruni et al., 2004;Azah et al., 2005;bin Jantan et al., 2005). Methylcinnamate, a known component of the floral scent from various orchid species, acts as a preferred attractant for euglossine bees and is electrophysiologically active toward excised bee antennae (Dodson et al., 1969;Ackerman, 1989;Schiestl and Roubik, 2003;Eltz and Lunau, 2005). ...

Secondary metabolites of Escallonia illinita Presl.
  • Citing Article
  • January 1990

... including antioxidant (Lopez et al., 2008;Nunes et al., 2016;Telichowska et al., 2021;Sureshkumar et al., 2021b), wound healing (Hayat et al., 2011;Carmignan et al., 2020), antimicrobial (Garcia et al., 2013;Alves et al., 2016;Yeganegi et al., 2018;Sureshkumar et al., 2021b), anti-ulcerogenic (Yesilada and Gurbuzb, 2010;Naghmana et al., 2021), antiproliferative (Grundemann et al., 2014;, hepatoprotective (Oh et al., 2004;Jin et al., 2014), anti-hypertensive (Adsersen and Adsersen, 1997), antidiabetic , 2000a, 2000bVieira et al., 2020), anti-inflammatory (Farinon et al., 2013;Shiba et al., 2020), anti-convulsant (Rassouli et al., 2009), anticancer (Mohammed et al., 2017), and antitumor effects (Jabeur et al., 2017). Particularly E. arvense, E. bogotense, E. fluviatile, E. gigantium, E. hyemale E. affine, E. myriochaetum, and E. ramosissimum are some of the important species in treating urinary tract infections with potential diuretic properties (Perez Gutierrez et al., 1985;Rodriguez et al., 1994;Lemus et al., 1996;Carneiro et al., 2014;Zhang et al., 2015;Boeing et al., 2021). The plant extracts which were tested for in vitro and in vivo toxicity studies also revealed that there was no noticeable cytotoxicity, genotoxicity, and hepatotoxicity (Milovanovic et al., 2007;Tago et al., 2010;Uslu et al., 2013;Zhang et al., 2015;Albadri, 2016;Kour et al., 2017). ...

Diuretic activity of an Equisetum bogotense tea (Platero herb): Evaluation in healthy volunteers
  • Citing Article
  • November 1996

Journal of Ethnopharmacology

... Current data from both in vitro and in vivo studies indicate that it has many antiviral, anti-inflammatory, anti-allergic, antiseptic, antipruritic, and antinociceptive properties, as well as an immunomodulatory effect against sperm immobilization (Kaur & Kapoor, 2002;Kumar et al., 2007). Similarly, it has antispasmodic (García et al., 1997), antiparasitic (Giove Nakazawa, 1996), antimicrobial, antifungal (Maksimović et al., 2005, and antioxidant properties and is beneficial for people who suffer from peptic ulcers and heart disease (Laghari et al., 2011;Mousavi et al., 2005;Poonia & Upadhayay, 2015;Saini et al., 2019). Chenopodium album leaves are used to treat kidney and urinary tract disorders, to purify blood, to protect people from contracting roundworms and hookworms (anthelmintic), to induce laxation, and to treat liver diseases, splenomegaly, burns, and intestinal ulcers (Sarma et al., 2008). ...

Biological and chemical study of paico (Chenopodium chilense, Chenopodiaceae)
  • Citing Article
  • August 1997

Journal of Ethnopharmacology

... It is also utilized as an antipyretic and carminative medication [4]. Furthermore, Lemus et al. [5] reported that R. ulmifolius was used in traditional Chinese medicine for its hypoglycemic properties. Its leaves and young shoots have also been utilized for their beneficial properties, which include their anti-inflammatory, antimicrobial, and spasmolytic effects on the gastrointestinal tract. ...

Hypoglycaemic activity of four plants used in Chilean popular medicine
  • Citing Article
  • March 1999

Phytotherapy Research