I. Mizuno's scientific contributions

Publication (1)

Article
We newly produced an aged garlic extract preparation combined with ginseng, oriental bezoar, antler velvet, cuscuta seed and epimedium herb (LEOPINROYAL; LER), and examined whether it would improve peripheral blood circulation, as determined by the cooling-rewarming test in mice, or by a four-week trial in humans. In the mouse cooling-rewarming tes...

Citations

... In another clinical study, AGE has been shown to enhance cutaneous microcirculation in patients with the increased risk of cardiovascular events (42). In addition, an animal study demonstrated that AGE can reverse the decrease in the rectal temperature of mice induced by cooling (32,43). Furthermore, administration of S1PC, a characteristic constituent of AGE increased the blood flow of tail skin in spontaneously hypertensive rats (SHR) (21). ...