I. Dolapci's research while affiliated with Ankara University and other places

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Publication (1)

Efflux gene expressions in ST131 and non-ST131 isolates
The Role of AcrAB–TolC Efflux Pumps on Quinolone Resistance of E. coli ST131
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  • Dec 2018
Escherichia coli ST131 is a cause for global concern because of its high multidrug resistance and several virulence factors. In this study, the contribution of acrAB–TolC efflux system of E. coli ST131 to fluoroquinolone resistance was evaluated. A total of nonrepetitive 111 ciprofloxacin-resistant E. coli isolates were included in the study. Multi...
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... AcrA is one of the components of the trimeric ABC transporter AcrAB-TolC. 29 The overexpression of this transporter plays a role in the efflux of fatty acid or biliary acid within the intestine and produces fluoroquinolone resistance. AcrAB-TolC expression is induced by exposure to organic anions such as the carboxylic acid group. ...
Reference: The Drug-Specific Propensity Regarding the Acquisition of Fluoroquinolone Resistance in Escherichia coli: An in vitro Challenge and DNA Mutation Analysis
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