Hung Tuck Chan's research while affiliated with University of the Ryukyus and other places

Publications (32)

Article
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Globally, there are eight species of Avicennia with five species (A. alba, A. integra, A. marina, A. officinalis and A. rumphiana) in East Africa and Indo-Pacific, and three species (A. bicolor, A. germinans and A. schaueriana) in the New World and West Africa (Duke, 1991; Spalding et al., 2010). Avicennia species occur in tropical, subtropical inc...
Chapter
This chapter on Mangroves of Malaysia begins with a brief introduction on the geography of Malaysia, consisting of Peninsular Malaysia, Sabah, and Sarawak separated by the South China Sea. Information on the population, land area, and area of mangroves in Malaysia is presented. The largest area of mangroves is in Sabah, followed by Sarawak and Peni...
Article
In this article, the botany, uses, bioactive compounds and pharmacological properties of leaves and roots of Pluchea indica are reviewed for the first time. The coastal species occurs in open sites at the landward side of mangroves. Main botanical characters for the identification of P. indica are bushy shrub life-form, and leaves are short-stalked...
Article
Rosemary (Rosmarinus officinalis L.), a culinary herb of the family Lamiaceae, has promising anticancer activity. This overview has updated the current knowledge on the chemistry and anticancer properties of rosemary extract, carnosic acid, carnosol, and rosmanol, focusing on colon and prostate cancer cells since they are the most susceptible. The...
Article
Tetrandrine (TET) and fangchinoline (FAN) are dominant bisbenzylisoquinoline (BBIQ) alkaloids from the roots of Stephania tetrandra of the family Menispermaceae. BBIQ alkaloids comprise two benzylisoquinoline units linked by oxygen bridges. The molecular structures of TET and FAN are exactly the same, except that TET has a methoxy (−OCH3) group, wh...
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Mangroves dominate natural shorelines of Sabah and occupied approximately 60% of the total mangroves of Malaysia, yet their utilization by fishes, shrimps and other marine fauna is poorly understood. The focus of this notes is to identify the importance of mangrove habitats in relation to assemblage-level patterns of fish use, with very few studies...
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Flavonoids are by far the most dominant class of phenolic compounds isolated from Morus alba leaves (MAL). Other classes of compounds are benzofurans, phenolic acids, alkaloids, coumarins, chalcones and stilbenes. Major flavonoids are kuwanons, moracinflavans, moragrols and morkotins. Other major compounds include moracins (benzofurans), caffeoylqu...
Article
Background and aims: The tidal flats on which mangrove plants grow tend to have low soil nitrogen contents because nitrogen-containing litter is repeatedly washed offshore by ebb tides. Under such circumstances, it is unclear how mangrove plants acquire the nitrogen required to support their vigorous growth. In the present work, chemical and biolo...
Article
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Flavones are the most dominant type of flavonoids isolated from the roots of Scutellaria baicalensis (Radix Scutellariae), which is a traditional medicinal plant in East Asian countries, including China, Japan and Korea. Most of the flavones are derivatives with methoxyl and hydroxyl groups, and they include baicalein, baicalin, chrysin, norwogonin...
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The root bark of Morus alba L. or white mulberry is widely used as traditional medicine in China, Japan and Korea. Major classes and types of phenolic compounds isolated from the root bark are flavonoids (kuwanons, morusin, cyclomorusin and sanggenons), benzofurans (moracins and mulberrofurans), and stilbenoids (mulberrosides). Some of the flavonoi...
Article
This short review provides an update of the anticancer and anti-inflammatory properties of casticin from Vitex species. Casticin is a polymethylflavone with three rings, an orthocatechol moiety, a double bond, two hydroxyl groups and four methoxyl groups. Casticin has been isolated from various tissues of plants in the Vitex genus: fruits and leave...
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In this review, the botany and uses of Alpinia zerumbet (yan shan jiang) are described, and the current knowledge of its phytochemistry, pharmacological properties, and clinical trials is summarized. An important ginger crop in East Asia, A. zerumbet has many uses, both medicinal and non-medicinal. Leaves are used to produce essential oils and herb...
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From different plant parts of Calotropis species (C. gigantea and C. procera), various classes of compounds such as oxypregnanes, terpenoids, sterols, cardenolides and flavonoids have been isolated. Of these compounds, the cardenolides stand out as many of them have anticancer properties. Cardenolides are C23 steroids with a five-membered unsaturat...
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Mangifera pajang Kostermans of the mango family (Anacardiaceae) is endemic to the lowland rain forests of Borneo. Although growing wild in the forest, trees of are planted in orchards and home gardens due to increasing demand for the fruits which are among the largest of the genus. Fruits are oval in shape, and have a characteristic rough and brown...
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The phytochemistry and pharmacology of two common tree species of sandy shores, namely, Calophyllum inophyllum and Thespesia populnea have been selected for review. There was global interest in C. inophyllum after its leaves were reported to possess anti-human immunodeficiency virus (HIV) properties. Since then, extensive research has been conducte...
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In Southeast Asia, ulam herbs are consumed raw as a condiment. It is believed that these herbs have medicinal benefits and their regular intake can prevent degenerative diseases, delay aging and improve overall health. In this review, the current knowledge on the phytochemistry and pharmacology of Oenanthe javanica (water dropwort) and Cosmos cauda...
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Apocynaceae is a large family of tropical trees, shrubs and vines with most species producing white latex. Major metabolites of species are triterpenoids, iridoids, alkaloids and cardenolides, which are known for a wide range of biological and pharmacological activities such as cardioprotective, hepatoprotective, neuroprotective, anti-inflammatory,...
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Among the Hibiscus species, H. tiliaceus and H. mutabilis display spectacular flower colour change. In this short review, the current knowledge on their phytochemistry and pharmacology is updated, and their botany and uses described. With phytosterols, triterpenes, triterpenoids, coumarins, amides, phenolic acids, and anthocyanins as chemical const...
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Artocarpus altilis (breadfruit) and Pandanus tectorius (screw pine) are two cultural icons of Oceania. Fruits of both species are rich in carbohydrates, and contain proteins, vitamins and minerals. Endowed with triterpenes, flavonoids, stilbenes, arylbenzofurans and sterols as chemical constituents, fruits of A. altilis possess antioxidant, antimic...
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Xylocarpus of the family Meliaceae is a small genus comprising tree species of X. granatum, X. moluccensis and X. rumphii (Giesen et al., 2007). Considered as true mangroves, X. granatum and X. moluccensis are found at the landward side of mangrove forests and in associated brackish-water habitats while X. rumphii occurs along rocky shores and prom...
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Metabolites and bioactivities of Rhizophoraceae including Rhizophora stylosa have only been reviewed by Nebula et al. (2013). In a review of natural products from mangrove flora by Wu et al. (2008), information on R. apiculata and R. mucronata was presented but not on R. stylosa. In this note, the chemistry and bioactivities of R. stylosa, which ar...
Article
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Members of the mangrove genus Rhizophora represent the most commonly occurring and highly valued species in the Indo-West Pacific region. However, to date, few studies have been directed towards the understanding of their genetic variation. The levels and patterns of genetic variation at chloroplast and nuclear gene regions were studied in R. apicu...
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Natural hybridization is common in plants. Very often, the identity of a putative hybrid is inferred based on the observation of morphological features intermediate between two possible parental species occurring in a specific location. However, due to plasticity of morphological features and the co-occurrence of more than two possible parental spe...
Article
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The objective of this trial is to test the feasibility of cluster planting technique and to identify suitable species for rehabilitation.

Citations

... Tetrandrine (Figure 4), a bisbenzylisoquinoline alkaloid derived from the roots of a medicinal plant, Stephania tetrandra, has exhibited promising antineoplastic activities in tumor models [266][267][268]. Tetrandrine demonstrated inhibition of growth and angiogenesis, promotion of apoptosis, and cell cycle arrest in 786-O and 769-P cell lines. ...
... In China, mulberry leaf is also a medicinal resource which is widely used in traditional Chinese medicine [5]. Mulberry leaves contain a variety of functional components, such as alkaloids, polyphenols and flavonoids, proteins, amino acids, and carbohydrates [6][7][8][9]. A variety of functional components endow mulberry leaves with different biological activities, such as hypoglycemic, anti-atherosclerotic, antioxidant, and antibacterial activities [10][11][12][13]. ...
... Although successive monitoring of plant growth after planting has been conducted in some afforestation stands (Samson and Rollon 2008;Sillanpää et al. 2017), the soil environmental changes accompanying plant growth have not been measured in most stands. On the other hand, some field studies in natural mangrove forests have suggested that mangrove roots interact with nitrogen-fixing bacteria (Inoue et al. 2011a;Inoue et al. 2019;Inoue et al. 2020) and arbuscular mycorrhiza . A cultivation experiment has revealed increases in phosphate ion (PO 4 − ) and ferrous ion (Fe 2+ ) concentrations in mangrove-rooted soil pore water (Inoue et al. 2011b), and a field study has noted high nitrate ion (NO 3 − ) concentration near mangrove roots (Inoue et al. 2011a). ...
... Recently, there has been significant progress in clarifying the specific mechanisms and underlying signalling pathways of baicalein's anticancer activities. Baicalein can treat a wide spectrum of human cancers by regulation of various cell signalling pathways, including attenuating mitogen-activated protein kinase (MAPK), Akt, and mTOR activity; inhibiting tumour invasion through inducing apoptosis by activating caspase-9/-3; decreasing the expression of matrix metalloproteinase-2/-9; inhibiting complexes of cyclins from regulating the cell cycle; scavenging oxidative radicals and inhibiting angiogenesis, metastasis, and inflammation (Chan et al., 2019;Gao et al., 2016;Hui et al., 2016). Currently, the studies of baicalein's on anticancer effects have mostly been conducted in animals and involved studies of the above mechanisms. ...
... Phenological studies on the natural A. cucullata population in Ranong will be useful in determining the season for collecting mature fruits and seeds for raising in the nursery prior to outplanting in the field. Although A. cucullata was one of the species chosen for the mangrove rehabilitation project in Sabah (Baba et al., 2019), and planted in clusters along Sungai Garama (Tangah et al., 2012), its silviculture needs to be studied including nursery and planting techniques, growth and yield, and pests and diseases. ...
... Casticin, a polymethyl flavone with a molecular formula of C19H18O8, is derived mainly from the Vitex species of the family Verbenaceae (Chan et al., 2018). The main pharmacological properties of casticin include anti-inflammatory, anticancer, anti-asthmatic, anti-angiogenic, immunomodulatory, analgesic activities, etc. (Chan et al., 2018). ...
... A. zerumbet (Pers.) B.L. Burtt & R.M. Sm, also known as shell ginger or yan-shan-jiang in China, is native to East Asia and Brazil and widely cultivated in tropical and subtropical zones of the world [113]. The leaves have been used in tea, and some research supports an association with life extension in Japan [49]. ...
... It is an excellent source of different minerals, vitamins, dietary fiber, and secondary metabolites. It is used as traditional Chinese medicine for the treatment of many diseases [6][7][8]. Phytochemicals extracted from water dropwort have several pharmacological activities: antioxidant activities, anti-inflammatory, anti-arrhythmic, anti-hepatitis B virus, hepatoprotective, antidiabetic, and anticancer [5,7,9]. Due to its particular aroma and flavor, it is used for garnishing different dishes and salads. ...
... Plenty of polyphenol compounds have been identified in M. pajang parts including kernel, peel and pulp [9]. It was reported that M. pajang kernel had a 17 times higher amount of phenolic compounds than the pulp and peel [10]. Moreover, methyl gallate (MG) isolated from M. pajang kernel was the only compound with high antioxidant activity [8]. ...