Huiping Yan's research while affiliated with Beijing children's hospital of Capital Medical University and other places

Publications (2)

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Aim Tauroursodeoxycholic acid (TUDCA) is a taurine conjugated form of ursodeoxycholic acid (UDCA) with higher hydrophility. To further evaluate the efficacy and safety of TUDCA for primary biliary cholangitis (PBC), we performed this study on Chinese patients. Methods 199 PBC patients were randomly assigned to either 250 mg TUDCA plus UDCA placebo...


... Currently, there is one clinical trial evaluating its use in PSC patients (NCT01755507). A recent study has shown that TUDCA was able to normalize serum ALP values in PBC patients [43]. Another FXR agonist with therapeutic potential in the treatment of cholestatic diseases is the semi-synthetic BA, obeticholic acid (OCA). ...