Huiping Li's research while affiliated with Lund University and other places

Publications (36)

Article
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Background Salivary amylase, encoded by the AMY1 gene, initiate the digestion of starch. Whether starch intake or AMY1 copy number is related to disease risk is currently rather unknown. The aim was to investigate the association between starch intake and AMY1 copy number and risk of cardiovascular disease (CVD) and mortality and whether there is a...
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To investigate the associations of milk intake (non-fermented and fermented milk), lactase persistence (LCT-13910 C/T) genotype (a proxy for long-term non-fermented milk intake), and gene-milk interaction with risks of cardiovascular disease (CVD) and CVD mortality. Also, to identify the CVD-related plasma proteins and lipoprotein subfractions asso...
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Objectives The detrimental association of mortality with sleep apnoea may increase with apnoea severity. To assess the association between life-course severe sleep apnoea and all-cause mortality and to investigate whether and to what extent the association was compensated by physical activity. Methods The prospective cohort study included 407,128...
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Objective to examine the association between different patterns of impaired lung function with the incident risk of dementia and magnetic resonance imaging (MRI)-based brain structural features. Methods in UK Biobank, a total of 308,534 dementia-free participants with valid lung function measures (forced expiratory volume in 1 s [FEV1] and forced...
Article
Older adults have been markedly impacted by the coronavirus disease 19 (COVID-19) pandemic, and many reports have cited concerns regarding potential psychiatric sequelae of coronavirus disease (COVID-19), but the actual effects of psychotropics on the COVID-19 are unclear. In this study, multivariate logistic regression was used to evaluate associa...
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Objective: We aimed to prospective investigate the association between cardiometabolic diseases (CMDs) with dementia, and to examine whether genetic factors and CMDs jointly contribute to the incidence of dementia. Methods: We used data from the UK biobank of 204,646 adults aged 37-73 free of dementia at baseline. Genetic risk for dementia includin...
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It has been suggested that added sugar intake is associated with non-alcoholic fatty liver disease (NAFLD). However, previous studies only focused on sugar-sweetened beverages; the evidence for associations with total added sugars and their sources is scarce. This study aimed to examine the associations of total added sugars, their physical forms (...
Article
Objectives Atherosclerosis has become a leading public health problem. Previous studies suggest that enhanced muscle strength and muscle-derived cytokines (myokines) are linked with atherosclerosis. However, no previous prospective study has examined the relationship between grip strength (GS) and carotid atherosclerosis (CAS) in middle-aged and ol...
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Background and aims Concerns regarding adverse events associated with the use of acid suppressants have increased. However, the impact of proton pump inhibitors (PPIs) and histamine‐2 receptor antagonists (H2RAs) on the risk of atherosclerotic cardiovascular diseases (ASCVDs) remains unknown. This study aimed to estimate the risk of ASCVDs in assoc...
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Parkinson’s disease (PD) and cardiovascular disease share many important risk factors, but some associations differ. However, there are no studies that have compared their shared and specific risk factors. The present study aimed to compare risk factors for PD, coronary events, or ischemic stroke. We prospectively analyzed data from 26,210 particip...
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Purpose Nutrition plays a key role in supporting the human immune system and reducing the risk of infections. However, there is limited evidence exploring the relationship between diet and the risk of COVID-19. This study aimed to assess the associations between consumption of ultra-processed foods (UPF) and COVID-19 risk. Methods In total, 41,012...
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Background There has been a growing body of evidence associating consumption of ultra-processed foods (UPF) with adverse health outcomes including depression, cardiovascular disease, all-cause mortality. However, whether UPF are associated with dementia is unknown. The authors investigated the associations between UPF and dementia incidence in UK b...
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This study aimed to evaluate the longitudinal association between sweet potato intake and risk of NAFLD in the general adult population. In total, the number of 15,787 participants (males, 42.4%) was included in this prospective cohort study. Sweet potato intake was assessed by using a validated food frequency questionnaire. NAFLD was diagnosed by...
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Background The prospective studies on the effect of particular type of tea consumption, especially green tea, on depressive symptoms are limited. Objective The aim of this study is to investigate the prospective association between green tea consumption and depressive symptoms in a large general adult population. Methods This prospective cohort s...
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Prospective cohort studies linking organ meat consumption and nonalcoholic fatty liver disease (NAFLD) are limited, especially in Asian populations. This study aimed to prospectively investigate the association between organ meat consumption and risk of NAFLD in a general Chinese adult population. This prospective cohort study included a total of 1...
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The purpose of this cross-sectional study is to determine the association between yogurt consumption and lipid profiles in the general Chinese population. In this cross-sectional study, a total of 26,824 participants were included from Tianjin, China. Lipid profiles were determined by automated biochemical analyser. Yogurt consumption frequency was...
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Background : Evidence is limited regarding the impact of comprehensive mental health on the risk of subsequent cardiovascular events. Objectives : To investigate the association of mental health status with cardiovascular disease (CVD) in the UK Biobank. Methods : This prospective study included 339,616 participants aged 40 to 69 years who were e...
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Background: Basic studies have found that xanthine oxidase inhibitors extracted from mushrooms have inhibitory effects on hyperuricemia. However, the association between mushroom consumption and hyperuricemia is unknown in humans. Objective: We therefore designed a large-scale cohort study to examine whether mushroom consumption is a protective fac...
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Objective Prospective cohort studies linking dietary patterns and hyperuricemia (HUA) are limited, especially in Asian populations. This study aimed to prospectively investigate the association between various dietary patterns and risk of HUA in a general adult population. Method We used data from the Tianjin Chronic Low-grade Systemic Inflammatio...
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Background There is ongoing debate about the associations between drug therapies targeting the renin–angiotensin–aldosterone system (RAAS) and adverse outcomes in coronavirus disease 2019 (COVID-19).Objective This study aims to examine the associations between using medications for the cardiovascular system and the risks associated with COVID-19 in...
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Background: Sarcopenia is an aging-related loss of muscle mass and function, which induces numerous adverse outcomes. Capsaicin and capsiate, separately extracted from chilies and sweet peppers, have the potential to induce muscle hypertrophy via activation of transient receptor potential vanilloid 1. The present study aimed to investigate whether...
Article
Background and Aims Results of in vitro and in vivo studies showed that green leafy vegetables (GLV) could attenuate liver steatosis. However, little is known regarding the association between GLV intake and nonalcoholic fatty liver disease (NAFLD) in human. We examined the association of GLV intake with NAFLD in a large-scale adult population. Me...
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Background: Animal studies have shown that soy protein and isoflavones can increase antioxidant capacity and improve insulin resistance, and thus ameliorate nonalcoholic fatty liver disease (NAFLD). However, only limited epidemiological studies have examined the association of soy food intake with NAFLD. Objectives: We investigated the associati...
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PurposeThyroid hormones (THs) have multiple effects on lipid synthesis, mobilization, and degradation, suggesting that THs may affect the development of dyslipidemia. However, prospective studies on the association between serum THs levels and incident dyslipidemia in euthyroid subjects are limited. Therefore, we conducted a cohort study (~5-year f...
Article
Background & aims: Seaweeds are rich sources of anti-oxidants and anti-inflammatory properties, which are beneficial to non-alcoholic fatty liver disease (NAFLD). However, whether seaweed consumption is associated with NAFLD is unknown. We investigated the association of seaweed consumption with newly diagnosed NAFLD in a large-scale adult populat...
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Background Previous studies suggest that muscle-derived cytokines (myokines) are linked with brain function. Although muscle strength measured by handgrip strength is a prognostic indicator of functional decline, epidemiological studies directly examining the association between grip strength and mental health remain scarce. The aim of this study i...
Article
Background Research evidence supports a positive link between sugar-containing soft beverages and hyperuricemia. However, data thus far are mostly from Caucasian populations. And in sugar-containing soft beverages overall, sugar-containing carbonated beverages are purchased most often. Therefore, we investigated whether the high consumption of suga...
Article
Evidence has suggested that honey intake has a beneficial impact on glycemic control in patients with type 2 diabetes. Whether these findings apply adults with prediabetes is yet unclear. The aim of the present study was to examine whether honey intake is associated with a lower prevalence of prediabetes. A cross-sectional study was performed in 18...
Article
Background: Banana contains many kinds of substances that are beneficial to depressive symptoms. However, there are no epidemiological researches directly to explore the association between banana consumption and depressive symptoms. This study aimed to investigate whether the banana consumption is related to depressive symptoms in a general adult...
Article
Full-text available
Background: Red blood cell distribution width (RDW) was related with increased risk of mortality and adverse cardiovascular outcomes. However, it is uncertain whether RDW is related to the prevalence of atrial fibrillation (AF) in Asian population. The aim of this study was to assess the relationship between RDW and AF in a large Chinese populatio...

Citations

... Some recently published evidence focuses on relevant biomarkers related to AD and cardiovascular parameters, proving that poor vascular health does not significantly impact amyloid deposition but may have a direct and indirect effect on AD-related neurodegeneration [43,44,[54][55][56][57][58][59]. Aging acts through a number of biological mechanisms at the cellular or tissue level, which may lead to a multi-system loss of function and reserves. ...
... The COVID-19 pandemic has brought more challenge in disease burdens including neurological and mental disorders (70,71). The pandemic probably induces diet quality reduction (72,73,185) while poorer diet quality was accompanied with higher risks and severity of COVID-19 infection (186,187). In addition, pandemic increased the difficulty to access traditional treatments requiring in-person social interaction, resulting more and more patients without sufficient help and treatment (188). ...
... 19,20 However, few studies have investigated the association between UPF and cognitive decline in samples from high-income countries. [21][22][23] Therefore, we aimed to prospectively investigate the association between UPF consumption at baseline and cognitive decline in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). ...
... In addition, it exerts antidepressant effects. A prospective study with 7524 participants suggested that frequent green tea consumption was associated with a decreased risk of depressive symptoms in China (Dong et al. 2022). Green tea reduces depression and anxiety symptoms, and significantly reduces the levels of adrenal stress hormones in adolescents in Saudi Arabia (Almudhi and Gabr 2022). ...
... There was consistent evidence supporting a positive relationship between NAFLD and red and/or processed meat intake with RRs from 1.15 for total red meat [27] to 2.68 for red and processed meat [83], when comparing the highest versus lowest consumption level. Moreover, specific red and/or processed meats of hotdogs, hamburgers, bacon, and organ meat were significantly related to increased NAFLD incidence in various populations across the world [37,41,86]. In the NHS-II study, Kim et al. also regarded obesity as a significant mediator in the positive relationship between red meat consumption and NAFLD (mediation proportion of 66.1%) [41]. ...
... Maltodextrin, a polysaccharide chemically derived from starch, increased the adhesiveness of E. coli, stressed goblet cells, and thinned the protective mucus layer, causing bacterial translocation and colonic inflammation in mice [54]. A prospective cohort study that analyzed the 24-h diet recalls of 118,528 non-demented participants at baseline reported that participants who consumed ultraprocessed food had greater risk for dementia than those who consumed minimally processed foods [55]. ...
... Further, a recent study addresses the importance of incorporating neuroticism when examining the role of mental health and CVD, due to the relatively scarce research on neuroticism and CVD. Although neuroticism overlaps with symptoms of anxiety and depression, neuroticism might also have an independent association to CVD (Li et al., 2022). ...
... The formation of UA crystals is commonly caused by an increase in circulating UA, usually due to a defect in its excretion and/or reabsorption [103] and also by an incorrect diet [104]. In fact, it was demonstrated that dietary patterns rich in animal or sweet foods were positively associated with a higher risk for hyperuricemia, whereas the vegetable pattern was negatively associated [105]. Hyperuricemia has been associated with a variety of pathological conditions such as metabolic syndrome and coronary artery disease, all associated, from low to high degree, with sterile inflammation [106,107]. ...
... Several observational studies have shown that higher intakes of mushrooms and algae were associated with lower risks of cancer [11], hypertension [12], type 2 diabetes [13], hyperuricemia [14], and cognitive impairment [15]. A recent meta-analysis including five prospective studies reported an inverse association between mushrooms intake and total mortality [16], although inconsistent findings were observed across studies. ...
... In a cross-sectional study (n = 2451), the consumption of dietary chilli and sweet pepper (antioxidant rich) were evaluated using a self-administered food frequency questionnaire. 47 Higher consumption of chilli and sweet pepper was found to significantly correlate with a lower risk of sarcopenia, suggesting that capsaicins and capsiates (the active anti-inflammatory compounds in these foods) may be beneficial to prevent onset of sarcopenia. Additionally, some benefit of a diet rich in betaine was observed in a 4 year community-based study (n = 1996; aged 50-75 years), which found that higher levels of serum betaine correlated with greater levels of lean percentage body mass (LM%) and a decreased risk of having lower LM%. ...