Huayi Suo’s research while affiliated with Southwest University and other places

... that reinforce blood-brain barrier integrity and reduce neuroin- depression severity scores with probiotic co-administration [16][17][18][19]. Table 1 presents examples of the synergistic effects observed between nutraceuticals and pharmaceuticals, highlighting their combined therapeutic benefits. ...

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Nutraceutical-Pharmaceutical Synergy: Unlocking the Future of Precision Nutrition and Holistic Healthcare Nutraceutical-Pharmaceutical Synergy: Unlocking the Future of Precision Nutrition and Holistic Healthcare

... Notwithstanding, some studies have explored strategies to enhance postbiotic delivery to targeted sites in combination with prebiotics for a synergistic result upon interfacing with the intestinal microbiota [193]. Alternatively, there is a continuous evaluation of incorporating these combinations into food products to develop fermented and/or functional foods [194]. ...

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Probiotic, Postbiotic, and Paraprobiotic Effects of Lactobacillus rhamnosus as a Modulator of Obesity-Associated Factors

... Sex steroids, particularly testosterone and estradiol, are pivotal in regulating reproductive functions. However, their influence extends beyond reproduction, impacting various metabolic processes 8,9 . Associated with increased adipose mass, low testosterone is a phenomenon that places men at increased risk of developing insulin resistance 10 . ...

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Association between endogenous estradiol, testosterone, and long‐term mortality in adults with prediabetes and diabetes: Evidence from NHANES database

... Postbiotics have emerged as a promising therapeutic option for the prevention and treatment of IBD, given their stability and safety in comparison to live probiotics. Researchers have demonstrated that the administration of postbiotics obtained from Lacticaseibacillus rhamnosus notably mitigates the symptoms of UC by enhancing intestinal barrier integrity and lowering levels of inflammatory cytokines [78]. ...

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Recent Advances in Gut Microbiome Modulation: Effect of Probiotics, Prebiotics, Synbiotics, and Postbiotics in Inflammatory Bowel Disease Prevention and Treatment

... Beneficial effects of FMT include preserved intestinal barrier function, improved intestinal motility, production of SCFA or a reduced number of pro-inflammatory bacterial strains in the gut [181][182][183]. The potential benefit of FMT was reported, e.g., in obesity, cardiovascular disorders, epilepsy and cognitive impairment [184][185][186][187]. In the animal MPTP model of PD, FMT was shown to improve the composition of the gut microbiota, decrease α-synuclein expression, inhibit microglial activation in SN, block pro-inflammatory signaling pathways and reduce behavioral changes [188,189]. ...

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Microbiota, Tryptophan and Aryl Hydrocarbon Receptors as the Target Triad in Parkinson’s Disease—A Narrative Review

... Tissue injury is strongly associated with HUA, which is mainly caused by changes in the microenvironment in the body, including pH, redox balance, etc., thereby resulting in the imbalance of metabolic homeostasis (Chen et al. 2023;Meng et al. 2023). Previous studies showed that kidney injury was a major complication of HUA due to the deposition of large amounts of urate in the kidney . ...

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Bioactive Evaluation of Naringenin in Ameliorating Hyperuricemia‐Induced Liver Injury by Inhibiting Xanthine Oxidase

... For example, fermented soybeans at 37 • C enhance soybean flavor compared to those at 45 • C and 53 • C, while fermented soybeans at 45 • C and 53 • C enhance soy sauce-like flavor compared to those at 37 • C [5]. Although traditional soybean flavor products such as Douchi and Chi-flavor-type Baijiu are popular and accepted worldwide due to their prominent soybean flavor [6,7], there are only a few reports on the study of soybean flavor. It is speculated that the synergistic effects of multiple metabolic pathways and multiple genes may produce soybean flavor [5]. ...

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Characterization of the Key Aroma Compounds of Soybean Flavor in Fermented Soybeans with Bacillus subtilis BJ3-2 by Gene Knockout, Gas Chromatography–Olfactometry–Mass Spectrometry, and Aroma Addition Experiments

... It exhibits remarkable abilities for selfrenewal and self-organization, faithfully reproducing the functionality of its original tissue [109]. In contrast to the complexity of animal models and the simplicity of 2D cell culture models, organoids provide a more relevant and sophisticated platform for studying human-specific disease modeling, tissue developmental biology, and personalized medicine [110][111][112]. Additionally, organoid transplantation is gaining attention as a promising method for tissue or organ replacement and regeneration [108]. ...

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Current advances in understanding endometrial epithelial cell biology and therapeutic applications for intrauterine adhesion

... Hoentjen et al. found that a prebiotic combination of inulin-type fructans reduced colitis in HLA-B27 transgenic rats, linked to gut microbiota changes, and increased TGF-β [21]. Wang et al. showed that stachyose improved weight recovery, reduced colonic damage, and corrected microbiota imbalances in UC mice [22]. Lunken et al. reported that inulin-type fructans-enriched enteral nutrition (ENN) reduced colitis severity in a T-cell transfer model, promoting beneficial microbes ...

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Evidence-Based Complementary Therapies for the Management of Ulcerative Colitis

... S. mutans employs a diverse array of genes and pathways to establish biofilms, a process involving adhesion, aggregation, and the production of extracellular polymeric substances (EPS) (41). Adhesins and lectins mediate initial attachment to tooth surfaces and intercellular interactions (42). ...

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Decoding gene expression dynamics in planktonic and biofilm cells of Streptococcus mutans: regulation and role of mutanofactin genes in biofilm formation