Henry Eyring's research while affiliated with University of Utah and other places

Publications (623)

Article
This study addresses the effects of a health care system publicly disclosing patient ratings of some of its physicians. I find evidence that the disclosure leads to: 1) performance improvement as measured by the ratings and by objective quality measures, and 2) a bias among raters, whereby raters positively weight a physician’s published average ra...
Article
The plastic flow and elastic behavior of ceramic materials is treated using a statistical mechanical relaxation theory. It is found necessary to treat creep as involving two, and, in some cases, three relaxation mechanisms. The methods necessary for treating such non-Newtonian Dow are developed here for creep for the first time. The results obtaine...
Article
The fundamentals of diabatic reactions are briefly reviewed. The two important types of radiationless transitions at the crossover region of two potential surfaces are considered kinetically and rate formulations are given. The first type involves an appreciable activation energy in excess of the heat of reaction. The second does not. The reaction...
Article
The recombination of gaseous ions in the presence of third bodies is assumed to follow a sequence of two bimolecular steps: M + X+ MX+ and MX+ + Y− XY + M. The termolecular rate constants of the over-all processes are calculated for several ionized gases at various temperatures. For the calculation, the equilibrium internuclear separation and the c...
Article
First of all a survey is given of the theory of absolute reaction rates. This is followed by a discussion on the application of the theory to reactions in liquid media. Thereby a model of the liquid state is set up and from this an expression for the free energy of the components is developed.The theoretical considerations are also applied to stead...
Article
1)An examination of the geological formation of diamond indicates that they were formed at depth and under conditions of thermodynamics stability.2)While the literature contains no certain example of the artificial production of the diamond, it seems unlikely that this situation will long maintain.3)An explanation of some of the physical properties...
Article
The conformational effect of variations in electronic properties at the N3 position of purines, purine analogs, and cyclic AMP analogs are related to their biological properties. The effect of glycosidic conformation is demonstrated for the adenosine analogs 2-azaadenosine and 2-fluoroadenosine by both theoretical calculations and T1 relaxation mea...
Article
The electronic structures and spectra of some simple nucleoside derivatives with the formal structure of cytosine nucleoside are presented. The experimental spectroscopic information is obtained from the circular dichroism and absorption spectra. The first four circular dichroism bands of pi-pi* origin possess the same sign pattern previously repor...
Chapter
IntroductionRandom-Walk and Multi-Barrier KineticsGeneral Solution of the Transport EquationEigenvalues and Eigenvectors of the Matrix AConnection Formula between Two Potential ProfilesPerturbations on the Matrix AApplications to Diffusion Problems
Article
in the field. I t is generally agreed that the major chemical effects of high-energy ionizing radiation are produced by the low-energy secondary electrons. Hence, a complete discussion of "Chemical Species Produced by the Impact of Low Energy Electrons" would be another review of radiation chemistry. This article is rather arbitrarily limited to a...
Article
My ancestors were drawn together from northern Europe by the new Mormon religion. My mother's people, the Romneys and Cottams, migrated from around Preston, England, arriving in Nauvoo, Illinois in 1839. My grandfather, Henry Eyring, came from Cohurg in Germany, and Grandmother Eyring came from German Switzerland. My Eyring grandparents met while c...
Article
DOI:https://doi.org/10.1103/RevModPhys.35.577
Article
FROM less than 92 known elements, about a million compounds have been prepared by chemists. More than half of these compounds contain only four elements: carbon, hydrogen, oxygen and nitrogen. How is such a great number of combinations possible ?
Article
Ara-C at very low dosage has been reported to decrease the host toxicity of ara-AMP or ara-A in combination with 2'-deoxycoformycin, a potent adenosine deaminase inhibitor, while increasing the toxicity to intracerebral L1210 leukemia. The possibility of increasing the selectivity of ara-A by prior administration of ara-C is explored. The importanc...
Article
By means of the proposed adiabatic approximation model for vibrational redistribution [Lin, S. H. (1980) Chem. Phys. Lett. 70, 492-499], the calculations of various rate constants caused by different couplings have been given in detail. By two methods it has been demonstrated that the rate constant caused by the Born-Oppenheimer mechanism, correcte...
Article
The circular dichroism and electronic absorption of three simple model systems for cytidine and uridine have been measured to 190 nm. The molecular spectral properties (excitation wavelengths, oscillator strengths, rotational strengths, and polarization directions) and electronic transitional patterns were investigated by using wave functions of th...
Article
We have previously obtained explicit equations, which are based on the ideas of finite perturbation theory (FPT), for calculating NMR proton-proton coupling constant. Using this model and the INDO formalism, a simple closed-form expression for the coupling constant of the hydrogen molecule is developed. This expression has several unique features:...
Article
The magnetic circular dichroism of imidazole and its derivatives are calculated using the π-electron approximation, where the resonance integral is computed by using the formula plus higher order terms. The magnetic circular dichroism (MCD) spectra for the molecules are also presented. As a complementary procedure to the π-electron calculation, Mic...
Article
The significant structure theory of liquids is tested by evaluating the radial distribution function. The calculations are based on face-centered cubic quasi-lattice structure, and the fluctuation in volume is used to describe the thermal displacements of molecules. It is shown that the local structure of liquids has inhomogeneous distributions. Th...
Article
In this report we treat reaction rates, equilibrium theory, and irreversible thermodynamics as different aspects of a single discipline. In biological reactions the rate is ultimately controlled by enzymes and other proteins of complex structure and high molecular weight. The needed formalism can be placed in one-to-one correspondence with appropri...
Article
Cell membranes consist of lipid bilayers in which proteins are embedded. Many cell functions are carried out at the cell boundary which interface with water. Here we describe the response to an anesthetic of a lipid bilayer and of an enzyme separately. While both systems are markedly affected by anesthetics at appropriately high concentrations, the...
Article
We present the derivation of the general kinetic equations of diffusion and diffusion with interaction (or chemical reaction) on solid surfaces (or in dense media) by using the density matrix method. We indicate several problems to which this formalism applies and, in particular, discuss the damping effect on diffusion.
Article
Full-text available
Anesthetics expand cell membranes, and high pressures (about 10-15 MPa) antagonize the anesthetic action. It is also known that inhalation anesthetics expand elastomer membranes. The mechanism of pressure antagonism of anesthetic action on membrane expansion was investigated in the present study with Silastic membranes. Halothane increased the leng...
Article
In a self-consistent field calculation, a formula for the off-diagonal matrix elements of the core Hamiltonian is derived for a nonorthogonal basis set by a polyatomic approach. A set of parameters is then introduced for the repulsion integral formula of Mataga-Nishimoto to fit the experimental data. The matrix elements computed for the nonorthogon...
Article
In this paper we derive the generalized master equations for the S(1) system coupled with the S(2) system, with the S(1) and S(2) systems embedded in a heat bath. This formalism can be applied to a number of problems like vibrational redistribution, dynamic effect of vibrational relaxation on electronic relaxation in condensed media, etc. In this p...
Chapter
A viable supported shock wave has a definite structure. Such a shock moving into cold unburned explosive loses energy at first faster than energy is locally recruited from exothermic reactions. However, as time goes on, this situation monotonically changes and energy is paid back at an increasing rate until a maximum in the released energy is reach...
Article
An aqueous solution of non-ionic surfactants becomes suddenly turbid when heated to a critical temperature, known as the cloud point, and concomitantly expands the volume. The volume expansion is caused by release of structured water molecules from the hydrophilic polyoxyethyelene moieties. Inhalation anesthetics decreased the cloud-point temperatu...
Chapter
The preparation of potential energy surfaces in configuration space started a new approach to reaction kinetics.
Article
An important unfinished problem is the theory of transition from deflagration to detonation DDT. The understanding of this problem is critical for the safe handling of explosives. Some of the successes of deflagration and detonation theory are outlined. For detonation to occur in a cylindrical explosive, for example, one must remember that as a sho...
Article
The effects of dipoles and aromatic amino acid side-chain models on the absorption and optical activity of the rhodopsin chromophore were calculated by using perturbation theory, and the results were compared with those of a Pariser-Parr-Pople calculation for the unperturbed system. The interaction was assumed to result from purely electrostatic in...
Article
A cylindrical detonating explosive behaves like a non-Newtonian viscous fluid emerging from a cylindrical pipe. The expression for non-Newtonian viscous flow has been applied to detonating explosives. The resultant fit to emerging flame fronts from detonation is excellent for a wide variety of detonating explosives both for transients (at various t...
Article
Full-text available
The main purpose of this paper has been to study the high pressure effect on the resonance Raman scattering (RRS) of molecules in a dense medium. In deriving the RRS cross section under high pressure, a different approach from that presented in the previous papers has been used, and the resulting expression for the RRS cross section can be used to...
Article
Both solid-like and gas-like flow structures are considered in the calculation of viscosity of liquid (4)He using the significant structure theory of liquids. The predominance of quantum mechanical zero-point motion over that arising from thermal excitation is taken into account for the solid-like motion of molecules. The viscosity of liquid (4)He...
Article
The fit of the Eyring-Stover statistical survival theory was found to be precise when applied to diverse soil-related functions.
Article
The rotational strengths of the four longer wavelength transitions, B(2u), B(1u), and the two E(1u), of adenosine derivatives constrained in the syn form have been investigated theoretically and experimentally. The theory combines a complete neglect of differential overlap version S (CNDO/S) description of the base with a generalized bond exciton m...
Article
A theory is proposed to study the sensitivity of cylindrical explosives. Using the equations governing the conservation of mass, energy, and momentum, the equation of state, and Newtonian mechanics, we have derived the expression D = D(o)e(-a2/d), in which the apparent length of the reaction zone, a, takes into account burned and unburned explosive...
Article
Adsorption of procaine and tetracaine to the dipalmitoyl phosphatidylcholine monolayers at the air/water interface is analyzed in terms of two types of interaction: (1) between the phospholipid molecules and the ligand molecules, and (2) among the ligand molecules themselves. The presence of the phospholipid monolayer increases the surface concentr...
Article
The elementary transition state approach has been used to obtain a simple model theory for the Soret effect (thermal diffusion) and the Dufour effect. The flow of heat in the Dufour effect is identified as the transport of the enthalpy change of activation as molecules diffuse. The theory as now formulated applies only to thermodynamically ideal mi...
Article
The purpose of this paper has been to develop the theoretical treatment of the triboexcitation mechanisms due to the electric field effect and the pressure effect and to show how to analyze the triboluminescent spectra to determine the external factors that affect or induce the triboluminescence.
Article
The large kinetic zero-point motion of (4)He molecules has been properly taken into account in the significant structure theory of liquids in order to describe the liquidity of liquid (4)He. The Debye and the Bose-Einstein partition functions are used for the solid-like molecules of the normal fluid component and for the whole gas-like molecules, r...
Article
The significant structure theory has been successfully applied to an aqueous NaCl solution. Liquid water is assumed to have a domain structure and the ions are hydrated by water molecules. The partition function is composed of the partition function for the water and that for the salt, and the excess free energy term from the Debye-Hückel theory is...
Article
A pH-indicator dye, bromothymol blue, was used to probe the hydrophilic surface of dimyristoyl-, dipalmitoyl-, and distearoylphosphatidylcholine bilayer vesicles. The apparent pK of the surface-adsorbed dye was larger than the bulk pK value. The contribution of the choline positive charge on the dissociation constant of the dye adsorbed on the vesi...
Article
There appears to be a tendency to convert pH values into "hydrogen ion concentrations" using the antilog of negative pH values. The present communication describes the thermodynamic basis of pH to explain that the above procedure is erroneous and that pH values should be treated as primary variables. Acidity expressed by the hydrogen ion concentrat...
Article
This paper presents a theoretical analysis, based on a simplified one-dimensional model, of the response of an explosive to a wide range of light intensities. A primary result has been the identification and development of a relationship among the important critical parameters. Numerical results illustrating the relationship among the critical ligh...
Article
The purpose of the present communication has been to present the derivation of the vibrational relaxation rate constant for the case in which both phonons and the molecular rotation (three-dimensional) participate in the vibrational relaxation and to study the effect of molecular rotation on the vibration-vibration energy transfer in the condensed...
Article
A method is presented for localizing molecular orbitals, based on diagonalizing subunits of the density matrix. First, nonbonding orbitals are found by diagonalizing the monatomic subunits; then, diatomic sigma or pi bonding and antibonding orbitals are obtained from the diatomic subunits for all bonded pairs of atoms; finally, the delocalized pi-o...
Article
The significant structures procedure of liquids has been used to calculate the thermodynamic properties of solid C(2)H(4). Two degeneracy terms were used to describe the behavior in the vicinities of the two phase transitions. The calculated entropy and specific heat agree well with experimental results from a few kelvins to the melting point. Less...
Article
The significant structures procedure of liquids has been used to calculate the thermodynamic properties of solid C2H4. Two degeneracy terms were used to describe the behavior in the vicinities of the two phase transitions. The calculated entropy and specific heat agree well with experimental results from a few kelvins to the melting point. Less sat...
Article
The ability of polynucleotides or polynucleotide duplexes such as poly(I).poly(C) to induce interferon production is proposed to depend on the existence of certain stable glycosidic orientations. It appears that a slight increase in instability of 1--3 kcal/mole (1 cal = 4.184 J) in the conformational regions near 20 degrees, 80 degrees, and 160 de...
Article
The solution conformations of 2-substituted derivatives of 1-(beta-D-ribofuranosyl)benzimidazole have been determined by circular dichroism spectroscopy in aqueous solutions. It is shown that analogs with methyl, amino, or methylamino substituents at position 2 of the benzimidazole ring (position 8 of the purine ring) have predominantly anti confor...
Article
The antagonizing action of hydrostatic pressure against anesthesia is well known. The present study was undertaken to quantitate the effects of hydrostatic pressure and anesthetics upon the phase-transition temperature of dipalmitoyl phosphatidylcholine vesicles. The drugs used to anesthetize the phospholipid vesicles included an inhalation anesthe...
Article
The concept of localized orbitals is one of the most important links between quantum molecular physics and interpretive physical chemistry. Most spectroscopic data can be explained by models that resort wholly or in part to localization. A distinction should be made, however, between the transferability of localized orbitals and Hartree–Fock (HF) m...
Chapter
Transient luminescence induced by the high electric field present in E-jump experiments led to the first observation of the Destriau-effect in liquid solution.
Article
The thermodynamic model of hysteresis in phase transitions based on the regular solution theory, previously developed, was applied to the solid phases of C(1)H(4) and C(2)H(4). The width and height of the hysteresis loops for these systems were calculated and compared with the experimental data; agreement was satisfactory.
Article
The thermodynamic model of hysteresis in phase transitions based on the regular solution theory, previously developed, was applied to the solid phases of C1H4 and C2H4. The width and height of the hysteresis loops for these systems were calculated and compared with the experimental data; agreement was satisfactory.
Article
The purpose of this paper is to study the conditions under which the rate constant exhibits the Arrhenius type of temperature dependence and the damping effect on the rate constant. According to the starvation kinetics, the rate of reaction is determined by the rate of energy flow in the high temperature range. We shall show that the rate of energy...
Article
Transient luminescence induced by high electric fields (>2.5 x 10(4) V/cm) was observed in aqueous solutions of 6,8-dihydroxypyrene-1,3-disulfonic acid. The light emission takes place both at the leading and the trailing edges of the perturbing electric square pulse. It occurs only during the variation of the applied field and disappears with a tim...
Article
The membrane model previously described [Hays, T.R., Buckwalter, C.Q., Lin S.H. & Eyring, H. (1978) Proc. Natl. Acad. Sci. USA 75, 1612-1615] for ion flow through a membrane is expanded to include the effect of binding of the mobile ion at the occupiable sites in the membrane. Two different effects were investigated: alteration of the association-d...
Article
Solutions of the simplified time-dependent Nernst-Planck electrodiffusion equations for various membrane models under the influence of a step voltage change are presented. Comparison of the results for a membrane with continuous sites to those for membranes with two, three or five intermediate sites shows little difference either qualitatively or q...
Article
The antiviral activity of ribavirin has been associated with its inhibition of the enzyme, IMP dehydrogenase. The ability of ribavirin to inhibit this enzyme has previously been shown to be related to its stability in the high anti glycosidic conformation. The antiviral effectiveness of several analogs of ribavirin have been investigated recently....
Article
Reactions that take place in shock waves are slow compared to the energy present in the translational degrees of freedom. One explanation for the slow burning in a detonation is that successive surface layers of the solid or liquid must react sequentially. Another mechanism, which can also account for the slowness of reactions in shock waves in gas...
Article
The actions of various kinds of so-called membrane-stabilizing drugs on Ca2+-induced flash intensity of purified aequorin, a photoprotein obtained from Aequorea aequorea, were examined. All drugs used in this experiment, including inhalational anesthetics, tetracaine, chlorpromazine, and morphine, depressed flash intensity, and the inhibition incre...

Citations

... Increasingly, individuals within-and even those external to-an organization know what employees earn, how they perform, and how employees and external constituents view the organization on various dimensions. 1 The many factors leading to such transparency include shareholders' demands for transparency in top executive pay; legal mandates such as California's "right to know" law for the salaries of state employees; organizational initiatives; internal employee requests for this information; and even the spontaneous sharing of such information by employees via the internet and websites such as glassdoor.com (Blanes i Vidal and Nossol 2011;Card et al. 2012;Song et al. 2018;Eyring 2020). While such information is often anonymized, in some cases it is not. ...
... It was suggested that hydrogen-bonds spanned between membrane components can play an important role in membrane behavior (Kamayaet al. 1980;Brockerhoff 1982;1986;Boggs et al. 1986;Cevc 1987). Some drugs were found to interrupt the hydrogen bonds (Kamaya et al. 1980;Brockerhoff 1982;Hanpft and Mohr 1985;Veiro and Hunt 1985) and thus to destroy the specific structural arrangement of the membrane components. Rearrangement of the hydrogen-bonds may play a role in the effect of the studied drugs on lipid-protein interactions and/or membrane proteins observed in this study. ...
... Specifically, for above reactions, reaction path was comprehended, potential energy surface (PES) was drawn, rate constant was calculated, anharmonicity was considered and kinetic parameter (A, n and E) was fitted. The theories and methods used mainly included transition state (TS) theory [40][41][42][43][44][45], Rice-Ramsperger-Kassel-Marcus based on master equation (RRKM-ME) [46,47], YL (Yao-Lin) method [9,10,36,37], Arrhenius equation [48], Least square method [49,50] and Goodness of fit [51,52]. In the future work, the kinetic parameters will be used to numerical simulation. ...
... In this paper, the boundary-value problem of plane-wave scattering by a chirally coated orthorhombic dielectric-magnetic sphere is solved in the framework of the transition matrix (or T-matrix). A chiral medium or an optical active medium is rotationally symmetric but not mirror symmetric, and in it there exist two eigenwaves, i.e. the left-and right-handed circularly polarized waves with different phase velocities [9,10]. Constitutive equations that are sufficient to describe a homogeneous, isotropic, reciprocal chiral medium macroscopically are the Drude-Born-Fedorov equations [11] D(r) = 0 r [E(r) + β∇ × E(r)] B(r) = μ 0 μ r [H(r) + β∇ × H(r)] ...
... where R is the Boltzmann constant. Enzyme catalysis is primarily driven by a decrease in the barrier height ∆ ‡ relative to the uncatalysed reaction, which in turn is thought to mainly arise from electrostatic effects [39,40]. Within semiclassical TST, ∆ ‡ is isotopedependent due in part to differences in zero-point energy for different isotopologues. ...