Helen Hughes's research while affiliated with Waterford Institute of Technology and other places

Publication (1)

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In the past two decades, biopharmaceuticals have been a breakthrough in improving the quality of lives of patients with various cancers, autoimmune, genetic disorders etc. With the growing demand of biopharmaceuticals, the need for reducing manufacturing costs is essential without compromising on the safety, quality, and efficacy of products. Batch...


... Proteins in solution are more prone to chemical and physical degradation processes which are hydrolytically driven [18]. They also require the cold chain which is a formidable logistical challenge that adds to the high costs of producing mAbs [19]. Thus, another benefit of formulating thermosensitive proteins into dry powders is the ease of transport and storage. ...