January 1964
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12 Reads
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7 Citations
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January 1964
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12 Reads
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7 Citations
December 1963
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7 Reads
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3 Citations
Progress in Brain Research
The widespread occurrence of threshold in the nervous system, and the importance of threshold in the details of neuronic activity, has been well known. Any large system that uses threshold as the criterion for whether transmission is to occur at each node is fundamentally unstable in its density of active points. Any increase in density, by increasing the chance that other stimuli will be successfully transmitted, tends to cause yet further increases in density. Calculation of the exact effects confirms the expectation. Were the threshold fixed, and were the conditions as assumed, any network using threshold would be erratic in action, tending continually to run away either to complete inactivity or to maximal activity. Since many processes in the nervous system are not normally seen to exhibit such runaways, there must be some factors opposing the primary instability. One is described briefly, showing that stabilization of a thresholded network is not difficult. The application of these facts to various symptoms seen in psychiatry is considered briefly.
December 1962
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67 Reads
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3 Citations
Any large system using only threshold as a criterion for whether transmission is to occur at each node is fundamentally unstable in its density of active points.Any increase in density of activity, by increasing the chance that other signals will be successfully transmitted, tends to cause yet further increases in density. Calculation of the exact effects confirms the expectation. Were the threshold fixed, and were the conditions as assumed, any network using threshold would be unstable in action, tending continually to run away to an extreme, either of activity or of inactivity. Since many processes in the nervous system are not normally seen to exhibit such runaways there must be factors apposing the primary instability. A possible factor is described briefly, to show that stabilization of a threshold is not difficult. The application of these facts to some well-known psychiatric symptoms is considered briefly. As an aid to the reader the main body of the report is given on white sheets. The appendices are to be found in the yellow section.
November 1962
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11 Reads
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35 Citations
Nature
May 1962
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17 Reads
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6 Citations
American Journal of Psychiatry
May 1962
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11 Reads
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14 Citations
Science
April 1962
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4 Reads
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1 Citation
Science
April 1962
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8 Reads
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12 Citations
Science
January 1962
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8 Reads
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7 Citations
If in the past somebody had asked about the fundamental difference between the animate and inanimate world, the most likely answer would have been: living organisms possess that unique feature of reproduction, the capacity of self-replication, while dead matter obviously does not have this power. Today, however, I would be hesitant to give this answer. We know by now of several schemes, even very simple schemes, which display the features of self-replication (Von Neumann, 1951; Lofgren, 1958) and in the course of this symposium you will be exposed to some interesting ideas on error correction (Lofgren, 1962) which is, in a sense, a more general case of self-reproduction. But I doubt whether we would classify systems displaying these features as “living organisms.” I certainly would not do so, because I believe that this capacity of self-replication is only a particular manifestation of a much more general principle which is the basis for all life. I shall come to it in a moment, after I have shown in a “Gedanken Experiment” that self-replication is not fundamental to life. Assume that I have a gadget which, by the flick of a switch, inhibits all meioses on this globe. As you may remember, meiosis is the chromosome-pair-splitting cell division which initiates oogenesis or spermatogenesis; hence, without meiosis, no sexual reproduction. Imagine that I turn on this switch. Certainly no drastic change will occur. We may happily live on as before, although after a while we may observe fewer and fewer people around us.
December 1961
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5 Reads
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28 Citations
Journal of the Optical Society of America
Modulation of light at 3 and 6 kMc is achieved by applying a superimposed electrostatic and microwave field to a carbon-disulfide Kerr-cell which is incorporated within the high-electric-field region of a resonant cavity. The development of this light shutter requires the analysis of the Kerr effect under circumstances in which the transit time of light is appreciable. A Kerr cell whose length is such that the transit time of light is one-half the period of the modulating microwave field proves to have particular advantages over other designs. The light shutter is realized with a re-entrant microwave cavity with provision for the application of electrostatic as well as microwave fields. At about 26-kv dc and 10-kw pulsed 3-kMc ac power, the system modulates a light beam of several milliwatts radiant power up to 80%.
... Take the example of stress: A social situation perceived as stressful elicits a response of the body's hypothalamus-pituitary-adrenal axis increasing the level of glucocorticosteroids in circulation, most importantly cortisol. This could be considered a 'trivial' response (von Foerster, 1962): stress input leads to hormone output -the same input always produces the same output according to a fixed and stable dose-response relationship. If bodies were trivial machines in von Foerster's sense, the stress axis would be a universal mechanism that responds in trivial, that is, stable and predictable, ways to changes in local environments. ...
January 1962
... • bionics (i.e., the application of biological methods and systems found in nature to the study and design of engineering systems), • bio-inspired computing (i.e., analyzing, formalizing, and implementing biological processes using computers), and • self-organizing systems. See [7]. ...
January 1964
... By contrast, the present model focuses on overall excitability of the network as a function of spatial heterogeneity of the functional properties of the gap junctions, rather than on the propagation of activity wavefronts and the spatial patterning of such fronts; these aspects have been considered elsewhere [4,32,47,48] . Whereas we considered the global activation threshold in an electrotonically coupled smooth muscle syncytium, a general argument regarding the all-or-none character of synaptically coupled networks, such as the central nervous system, was advanced by Ashby et al. [49]. This work has not considered heteromeric gap-junction channels with both Cx45 and Cx43 proteins. ...
November 1962
Nature
... Due to the aforementioned features, microwave photonics attracted considerable interest from the radar and optical societies since the 1960s [4,[177][178][179][180][181][182][183]. A number of photonics-based techniques have been developed over the past few decades, ranging from LO signal generation, waveform modulation, up-and down-conversion, distribution, beamforming, filtering, to analog-to-digital conversion, which covers almost all the RF modules in radars as shown in Fig. 5 except for antennas and amplifiers. ...
Reference:
Microwave Photonic Radars
December 1961
Journal of the Optical Society of America
... Modeling of bacterial growth in ecology usually makes use of the Monod equation to predict bacterial growth kinetics, and exponential decay functions are used to model bacterial decay (Wade et al., 2016). The Monod model can be improved by the use of population models, such as the von Foerster equation (M' Kendrick, 1925;von Foerster et al., 1960). By assuming the age or maturity dependence of the population (Stukalin et al., 2013;Rochman et al., 2018;Hadd and Lahbiri, 2022), one can model more complex phenomena, such as population fluctuations, which result from age-dependent decay and growth, and potentially such models could also be used to model the growth lag. ...
November 1960
Science
... Further continuous structure can be added, with early extensions to size and age structures proposed in Fredrickson and Tsuchiya (1963); Bell and Anderson (1967) and Sinko and Streifer (1967), for cell and animal populations, respectively. Generalisations to a p-dimensional "physiological state vector" were first made in Fredrickson et al. (1967), and we refer to Gyllenberg (1983); Webb (1985); Tucker and Zimmerman (1988); 7 Heinz von Foerster was a biophysicist with wide-ranging interests, including population growth; his "Doomsday equation" predicted that human population growth rate would become infinite (on November 13th, 2026) (Von Foerster et al., 1960). Tongue was firmly in cheek here, as the exact day coincided with what would have been his birthday. ...
December 1960
Science
... Previous studies showed that poverty, population density, literacy, distance to the road network, and residing in a rural area were associated with canine and human rabies [22,23]. For this study, we obtained several maps: a poverty raster map (approximately 1km resolution) of the proportion of people per grid square living in poverty in the FCT [20]; a literacy raster map (approximately 1km resolution) showing the proportion of men and women aged 15-49 per grid square as literate in the FCT [21]; an urban extent grid (v.1) showing the proportion of rural and urban areas in the LGA, extracted from the Global Rural-Urban Mapping Project (GRUMP v.1) [24]; and a population density map at 30 arc-second (~1 km at the equator) resolution from the World Pop project [25]. We used a 20-year average for land cover and population density. ...
July 1961
Science
... We have now set the stage to begin with the questions posed by von Foerster et al. (1960Foerster et al. ( :1292Foerster et al. ( - 1293) concerning the productivity of elements of a population as regards the net rate of growth. ...
May 1962
Science
... In Ref. 110 the exponent γ = 0.99 was declared, but taking into account the realistic fitting error ± 0.03, one obtains the hyperbolic equation shown on the right side of Eq. (11). The Doomsday or hyperbolic Eq. (11) met with extraordinary interest and strong criticism because of the spectacular prediction [111][112][113][114][115][116][117][118][119][120][121] . However, starting in the 1970s and 1980s, increasing deviations from Eq. (11) were observed, fortunately showing that von Forster Doomsday would not occur. ...
April 1961
Science