July 2022
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2,248 Reads
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133 Citations
Nature
Social-evaluative stressors—experiences when the self could be negatively judged by others—pose a major threat to adolescent health via their effects on internalizing disorders, such as anxiety and depression. Preventative interventions to help adolescents improve their responses to social-evaluative stressors, however, have rarely been effective. Here we show that replicable benefits for adolescents’ stress responses can be achieved with a short (~30-minute), scalable synergistic mindsets intervention. This intervention, which is a self-administered online training module, synergistically targets both growth mindsets (the idea that people’s intelligence can be developed in response to challenge) and stress-can-be-enhancing mindsets (the idea that people’s stress responses can fuel optimal performance). In six double-blind, randomized, controlled experiments conducted with youth in grades 8-12 and in undergraduate education, the synergistic mindsets intervention improved stress-related cognitions—the immediate target of the intervention (Studies 1-2, N = 3,472)—and a cascade of stress-linked outcomes: cardiovascular reactivity (Studies 3, N = 160; Study 4, N = 200), cortisol levels (Study 5, N = 118 students, n = 1,213 observations), psychological well-being (Studies 4-5), course pass rates (Study 5), and anxiety symptoms during the 2020 COVID-19 lockdowns (Study 6, N = 341). Evidence that the two mindsets worked synergistically came from heterogeneity analyses showing stronger effects among participants holding both negative mindsets at baseline (Studies 3, 5, and 6) and from a four-cell experiment that showed stronger effects of the synergistic mindsets intervention relative to changing single mindsets alone (Study 4). Confidence in these conclusions is rooted in a conservative, Bayesian machine-learning statistical method for detecting heterogeneous effects.