Hanan Aly Taha's research while affiliated with Beni Suef University and other places

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Publications (2)

Demographic and laboratory data of the studied groups.
Lymphocyte Subpopulations of the studied groups, Note : the ratio...
Correlation between Th17 and disease parameters.
Correlation between Treg and disease parameters.
Study of balance between T-helper 17 /T-regulatory cells in systemic lupus erythematosus and its relation to disease activity
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  • Mar 2019
Background and objectives: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that causes damage to many organs of the body. The balance between pro-inflammatory T-helper 17(Th17) and regulatory-T (Treg) cells play an important role in the pathogenesis of SLE. The aim of the study is to assess Th17/Treg ratio and their relation to...
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Fig. 1 Flow cytometric analysis for Th17 cells. (A) A patient with...
Fig. 2 Flow cytometric analysis for Treg cells. (A) A patient with...
Correlation between Th17 cells in studied groups and disease parameters
Correlation between Treg cells and disease parameters
Investigating the Balance between Th17/Treg Cells in Rheumatoid Arthritis and its Association with Disease Activity
Article
Full-text available
  • Jan 2019
Rheumatoid arthritis (RA) is a systemic autoimmune disorder characterized by articular inflammation and joint destruction. The mechanism of RA pathogenesis is not fully understood, but humoral and cellular immunity are known to be involved. CD4+ T lymphocytes and cytokines released by these cells are suggested to initiate inflammation in RA. This s...
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Citations

... 29,30 Consequently, Treg/T H 17 cell balance was proposed as a new paradigm for autoimmunity rather than the sole Treg state. 31,32 The present study revealed a significant increase in the frequency of AC and AA genotypes, and A allele among RA group compared to the control group. This was consistent with the results of studies on Iranian and Polish RA patients 3, 17 as well as on Turkish osteoarthritis (OA) patients, 13 where Foxp3 -3279 A allele was associated with a higher risk of disease than the wild type C allele. ...
Reference: Forkhead Box P3 (Foxp3) serum level and Foxp3 Gene-Promoter polymorphisms in Egyptian rheumatoid arthritis patients: A case-control study Ikram et al
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