Hai-Yun Shi's research while affiliated with Beijing Shijitan Hospital and other places

Publications (7)

Article
Background/Purpose Specific immunotherapy is the only effective etiological treatment for allergic rhinitis, but subcutaneous immunotherapy has a slow onset and poor compliance. Predicting the clinical efficacy of subcutaneous immunotherapy in advance can reduce unnecessary medical costs and resource waste. This study aimed to identify metabolites...
Article
Full-text available
The clinical epidemiological characteristics of chronic urticaria (CU) in different populations were not completely consistent, and the epidemiological characteristics of CU were very complex. At present, there were some patient-based studies on CU, but few natural population-based studied in the world.This study aimed to analysis the prevalence of...
Article
Full-text available
Background Allergic rhinitis is a common disorder that affects 10% to 40% of the population worldwide. Allergen immunotherapy (AIT) represents the only therapy that has the potential to resolve clinical symptoms of allergic rhinitis. However, up to 30% of patients do not respond to AIT. Biomarkers predicting the clinical efficacy of AIT as early as...
Article
Full-text available
Subcutaneous immunotherapy is the only treatment that improves the natural progression of allergic rhinitis and maintains long-term outcomes after discontinuation of the drug. Metabolomics is increasingly applied in the study of allergic diseases, including allergic rhinitis. However, little is known about the discovery of metabolites that can eval...
Article
Full-text available
Background: The aim of this study was to investigate the prevalence of epidemiologic and physician-diagnosed pollen-induced AR (PiAR) in the grasslands of northern China, and to study the impact of the intensity and time of pollen exposure on PiAR prevalence. Methods: A multistage, clustered and proportionately stratified random sampling with a...
Article
To evaluate the efficacy of Yupingfeng droppill and western medicine in treatment of allergic rhinitis, 76 patients from Beijing Shijitan hospital during April 2011 to May 2012 were selected and randomly divided into the treatment group (n = 44) and control group (n = 32). The treatment group was treated with Yupingfeng droppill and cetirizine tabl...
Article
To assess the effects of ambient air pollutants on hospital outpatient visits for allergic disease and pollinosis. The monitoring data of daily air pollution (SO(2), NO(2) and PM(10)) in 8 national monitoring and controlling sites of Beijing air quality, airborne pollen in 4 monitoring sites of Beijing, and daily meteorological data, along with the...

Citations

... Several other chemokines, and arachidonic acid pathway molecules also play roles in allergic inflammation. Patients with Artemisia pollen AR were treated with AIT for 1 year, and AIT responders increased leukotriene A4 hydrolase levels significantly than nonresponders [139]. Thrombin-activatable fibrinolysis inhibitor (TAFI) is known for the regulation of coagulation and fibrinolysis and also inactivates other inflammatory mediators [140,141]. ...
... Epidemiological studies showed that the prevalence of AR has increased progressively, and this clinical disorder approximately affected a billion people worldwide Meng et al., 2020). AR is highly heterogeneous with a wide range of severity, which has been subjectively evaluated by many symptom scoring scales, such as the total nasal symptom score (TNSS) and visual analogue scale (VAS) (Adamko et al., 2018;Shi et al., 2020). However, AR patients often do not realize how severe their symptoms are, and self-reported symptoms may hinder clinicians to evaluate the disease progression and adjust the treatment plan accordingly (Del Cuvillo et al., 2017;Han et al., 2019). ...
... Pollen, a type of aeroallergen, is an established risk factor for allergic rhinitis (AR) and asthma [1][2][3], but evidence for a relationship with chronic obstructive pulmonary disease (COPD) is still emerging. Pollen can trigger allergic inflammation which is IgE-dependent, but non-allergic inflammatory changes may still be possible [4]. ...
... Yu Ping Feng (YPF) decoction, a classic herbal formula, has been used in clinics to treat various diseases, such as respiratory tract infection 8,9 , nosocomial pneumonia 10 , chronic bronchitis 11 , and perennial allergic rhinitis 12 As a safe and effective formula, it has been reported to relieve idiopathic sweating and augment appetite in end-stage cancer patients 14 , prevent viral infections, such as severe acute respiratory syndrome 15,16 , and have immunoregulatory or beneficial effects in asthma 17,18 , hepatic-fibrosis 19 , pulmonary-fibrosis [20][21][22] , and dermatitis models 23 . Since explanations for the clinical application of YPF decoction have not yet been illustrated by the conventional method (such as the in vitro activity assays of selected compounds) due to difficulties in the experi- mental design of complex systems, its underlying mechanism remains to be explored. ...
... DM, however an association with distance to road (a proxy marker of exposure to traffic-related pollution) was shown among women. Zhuang et al., (2010) Beijing , ...