Hafiz Faisal Usman's research while affiliated with Punjab Forensic Science Agency and other places

Publications (7)

Article
Aim This case study will be beneficial for the forensic toxicology community for simultaneous detection of carbofuran, a pesticide and para-phenylenediamine (a hair dye locally known as black stone) along with their metabolites in analytically challenging samples like liver tissue and stomach contents. Introduction A 35 years old married woman was...
Article
A rapid colorimetric method for detection of p-phenylenediamine (PPD) in various biological samples is developed. The o-cresol test for acetaminophen detection has been modified to detect PPD in blood, urine, gastric contents, and liver. After precipitating protein with trichloroacetic acid solution (2 mL, 10% w/v), biological specimens were requir...
Article
Full-text available
Methanol has a widespread commercial use as a solvent in paints, varnishes, anti-freeze solutions and denaturant for ethanol. Exposure may occur due to accidental, suicidal ingestion or as a result of consuming adulterated liquor. Fatalities were reported in Pakistan in an incident after consuming methanol-tainted liquor. Postmortem specimens of ei...
Article
In January 2012, 664 cases of pyrimethamine toxicity and 151 deaths were reported among cardiac patients that had recently received free medicines from pharmacy of Punjab Institute of Cardiology, Lahore, Pakistan. These patients, ages ranged from 58 to 75 years, were prescribed simvastatin, clopidogrel, aspirin soluble, isosorbide mononitrate, and...
Article
A dead body of middle aged man was exhumed from 6.5 month earth-grave. Autopsy findings were non-specific as the body was completely putrefied. Deceased’s scalp hair and kidney was sent for toxicological analysis. Hair sample (50 mg) was incubated with 1 M NaOH (2ml). Chloroquine was detected in hair and kidney during basic drug screen performed on...
Article
Bloodstain pattern analysis has become a eld of specialization in Forensic sciences and plays an important role in the reconstruction of events at a crime scene. Research, books, and articles have been published on the analysis and interpretation of bloodstain patterns. We present a case study of a road traf c accident in which bloodstain pattern a...

Citations

... Under optimized conditions, the developed method was selective in the presence of acetaminophen, p-aminophenol etc. and was effectively applied to 13 severe cases of p-PDA poisoning. 34 Due to their unique optical and electrical properties, silver nanoparticles (AgNPs) enable strong localized surface plasmon resonance (LSPR) absorption with extremely sharp extinction bands and high extinction coefficients. 35 Hence, they behave as an ideal indicator for colorimetric detection. ...
... Adulteration also includes the use of ethylene glycol and methanol to raise the alcohol level and improve the taste of alcohol [13][14][15][16]. Despite the detection techniques of adulterants in alcohol, adulteration has remained a concern on local, national, and international scales [17][18][19][20][21][22]. The adulteration is done to decrease the production cost and increase the quantity of alcohol, it can be done in two ways, either by changing the concentration or by adding a substance like methanol. ...
... However, serious adverse reactions can results as reported in January 2012 in Pakistan. Isosorbide mononitrate tablets were contaminated with large doses of pyrimethamine (an antimalarial drug) which lead to the death of 151 patients and 664 cases of pyrimethamine toxicity [11]. ...
... Scientific literature describes several methods for identification and quantification of chloroquine. High-performance liquid chromatography (HPLC) [36][37][38] and gas chromatography [39][40][41] are commonly used to separate contaminants and increase sensitivity of chloroquine analysis in pharmaceutical and biological samples. Ultraviolet spectrophotometry [42][43][44][45][46][47][48], spectrofluorimetry [42,49], chemiluminescence [39], nuclear magnetic resonance [50,51] and immunoassay [52], and capillary electrophoresis [53] are also used for chloroquine analysis. ...
... Current methods for the detection of rodenticides mainly focus on human and animal samples like blood, serum, urine, or hair in a toxicological context [11]. More recently, also environmental exposure to rodenticides of wildlife has gained attention [12][13][14]. ...