January 2002
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4 Reads
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4 Citations
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... Agents that can alter the activity of Ca2+ channels or BKCa thus affect the vascular tone in both physiological and pathological conditions. Experiments [53, 54] showed that Tan IIA could block L-type Ca2+ channel, decrease concentration of intracellular Ca2+, ameliorate calcium overload in myocardiocytes, and prevent or even treat arrhythmia finally. Except for Ca2+ and K+, microRNA-1 (miR-1) level is also one of the important factors in ischemic arrhythmia. ...
January 2002