H C Zweng’s research while affiliated with Stanford University and other places

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Publications (34)


Diabetic Disk New Vessels—Correction
  • Article

January 1977

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2 Reads

American Journal of Ophthalmology

Hunter L. Little

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H. Christian Zweng

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Robert L. Jack

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Arthur Vassiliadis


Techniques of Argon Laser Photocoagulation of Diabetic Disk New Vessels

December 1976

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15 Reads

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27 Citations

American Journal of Ophthalmology

Four argon laser techniques have been evaluated in the eradication of diabetic disk neovascularization: focal (nonfeeder) photocoagulation, feeder-frond photocoagulation alone, panretinal photocoagulation alone, and feeder-frond treatment combined with panretinal photocoagulation. Focal photocoagulation was dangerous and the least effective technique in preventing recurrence of neovascularization. Feeder-frond photocoagulation was effective initially, but was associated with a high incidence of recurrent neovascularization. Panretinal photocoagulation and panretinal photocoagulation combined with feeder-frond treatment produced results superior to those obtained with the two earlier techniques. The best results were obtained with combined feeder-frond and panretinal photocoagulation done concurrently. Early diagnosis, aggressive photocoagulation therapy, and close follow-up were essential in order to obtain good results.



Recurrent Choroidal Neovascularization Following Argon Laser Photocoagulation of Histoplasmic Maculopathy

February 1975

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5 Reads

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37 Citations

International Ophthalmology Clinics

Early detection of recurrent or inadequately obliterated choroidal neovascularization can be achieved by repeating fluorescein angiography at one week and at one month after treatment. Immediate and intensely heavy photocoagulation of the recurrent vessels is recommended. Advisable settings are 200 μ. 400 mW. at 0.2 or 0.5 second, and 500 μ with 700 mW. at 0.2 or 0.5 second. Repeated slit lamp evaluation is advised until all fluid is resolved and all leakage on the angiogram is sealed. The patient is then followed up every six months, or earlier if he or she notes recurrent distortion on the Amsler grid, which the patient is advised to check three times weekly.


Argon Laser Photocoagulation in the Treatment of Presumed Histoplasmic Choroiditis

February 1975

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4 Reads

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3 Citations

International Ophthalmology Clinics

Our experience with the evolving techniques we have reported has not resulted in significant increases in visual acuity over pretreatment levels. However, argon laser photocoagulation, properly given, does destroy subretinal neovascularization. The most significant points of technique are (1) heavy treatment of the entire frond; (2) accomplishment of this usually by a 200-mu spot size, 0.2 to 0.5 second, at 300 to 400 mW. power; (3) the eye under retrobulbar anesthesia, and (4) following the case at intervals of three to five days until the neovascular frond is destroyed. If the edge of the neovascular frond is within 200 mu of the fovea, treatment presents a very definite hazard to foveal vision and should be attempted only in the most experienced hands and on only the best-informed patients.



Complications of argon laser photocoagulation

January 1974

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40 Reads

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78 Citations

Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology

The authors describe the most important complications that have occurred at time of treatment or within one week after treatment of a wide variety of retinal diseases with argon laser slit lamp photocoagulation, and describe the best methods to reduce the incidence and severity of such complications.




Citations (21)


... Indocyanine green (ICG) angiography reveals hyperfluorescent areas that correspond to leaking points, and the choroid appears partly hypofluorescent owing to RPE atrophy and partly hyperfluorescent owing to the choriocapillary hyperpermeability. [2][3][4] Optical coherence tomographic (OCT) examinations reveal subretinal fluid and an irregular profile of the internal margin of the neurosensory retinal detachment secondary to a thickening and elongation of photoreceptor outer segments. A double-layer sign may appear with an undulating RPE profile, a hyporeflective middle layer, and an intact or slightly thickened Bruch membrane. ...

Reference:

Chronic Central Serous Chorioretinopathy Imaged by Optical Coherence Tomographic Angiography
Diffuse retinal pigment epitheliopathy
  • Citing Article
  • January 1977

... Right after the invention of the laser by Maiman in 1960 [11], many more types of lasers were launched [12]. Moreover, pulsed lasers were studied as potential tools in biomedical applications [13,14], and only 5 years after its invention, the laser was used for precise tissue coagulation [15]. ...

Experimental Laser Photocoagulation* *From the Stanford University School of Medicine, the Palo Alto Medical Research Foundation, Palo Alto, and Optics Technology, Inc., Belmont, California.
  • Citing Article
  • September 1964

American Journal of Ophthalmology

... Following these criteria, 43 threshold data from ten studies were excluded 13,20,58,[64][65][66][68][69][70][71] and 253 threshold data published in 31 studies were found to be applicable for the purpose of model validation. 11,13,14,20,34,35,[54][55][56][57][58][59][60][61][62]65,67,[72][73][74][75][76][77][78][79][80][81][82][83][84][85] IV. ...

Ocular Laser Threshold Investigations
  • Citing Article
  • January 1971

... Protein denaturation occur at a temperature of about 60 °C [11]. A study by Peppers et al. (1969) indicated that thermal damage of the cornea starts at 67 °C [12]. Temperature differences of metal eye shields did not meet thermal value for protein denaturation despite application of high fluence and multiple laser pulses and omission of cooling methods. ...

Corneal Damage Thresholds for CO2 Laser Radiation
  • Citing Article
  • Publisher preview available
  • February 1969

... B Qiang Wu qiang.wu@shsmu.edu.cn 1 Department of Ophthalmology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China the clinical practice for diagnosing and monitoring NV [11]. However, ophthalmologists or specially qualified technicians and graders may need to manually analyze a few crosssectional OCT B-scan pictures from the volumetric scan slice by slice to identify NVD from OCTA images and determine blood flow information. ...

Techniques of Argon Laser Photocoagulation of Diabetic Disk New Vessels
  • Citing Article
  • December 1976

American Journal of Ophthalmology

... The argon green laser trial of extrafoveal CNV (200–2500 lm from the center of the foveal avascular zone) showed 25% and 60% severe visual loss in treated and untreated patients, respectively [14]. However, 59% of treated patients developed recurrent neovascularization, often soon after treatment (24% at 6 months, 43% by 1 year) [15]. The krypton red laser study treated juxtafoveal CNV lesions with a posterior border 1 to 199 lm from the center of the foveal avascular zone. ...

Recurrent Choroidal Neovascularization Following Argon Laser Photocoagulation of Histoplasmic Maculopathy
  • Citing Article
  • February 1975

International Ophthalmology Clinics

... In the current study, all patients who developed early postoperative VH were phakic, showed active fibrovascular membranes and none experienced ocular hypotony. Preoperative panretinal photocoagulation was not performed due to the risk of contraction of preretinal membranes [22][23][24], instead it was performed at end of surgery. To reduce the risk of intraoperative bleeding, IVB was injected 3-5 days prior to surgery in this series, but no more than 5 days to avoid causing fibrovascular contraction and subsequent worsening of the retinal detachment [25][26][27]. ...

Complications of argon laser photocoagulation
  • Citing Article
  • January 1974

Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology

... Способ доставки -ключевой аспект лазерной фототерапии. В то время как рубиновый лазер был адаптирован к монокулярному прямому офтальмоскопу, последующие поколения лазеров стали адаптировать к непрямому офтальмоскопу [4], щелевой лампе [5] и операционному микроскопу [6]. Сочетание лазеров со щелевой лампой улучшило доставку лазерного излучения, особенно для его применения в области заднего полюса глаза, что позволило проводить лечение широкого спектра заболеваний сетчатки и хориоидеи в амбулаторных условиях. ...

Argon Laser Slit-Lamp Retinal Photocoagulation
  • Citing Article
  • January 1970

Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology