July 2021
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48 Reads
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3 Citations
American Journal of Medical Genetics Part A
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July 2021
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48 Reads
·
3 Citations
American Journal of Medical Genetics Part A
... Similarly, there are reports of individuals with 15q13.3 deletion syndrome associated with schizophrenia, intellectual disability, epilepsy, aggression and autism spectrum disorders (ASD) where CHRNA7, the gene encoding the α7-nicotinic acetylcholine receptor subunit, is deleted (Casas-Alba et al., 2021;Cubells et al., 2011). The acetylcholinesterase inhibitor, galantamine, was observed to reduce aggression in one adult with psychosis and intellectual disability (Cubells et al., 2011) and improve fluid reasoning, working memory, and processing speed in one youth with ASD (Casas-Alba et al., 2021). ...
July 2021
American Journal of Medical Genetics Part A