Grania Brigden's research while affiliated with International Union Against Tuberculosis and Lung Disease (The Union) and other places

... On the other hand, the female sex was not a predictor of TB recurrence, implying that other vari- ables, such as smoking, alcohol consumption, and chronic obstructive pulmonary disease (COPD), could be confounding factors. Previous research has revealed that smoking, drinking, and being underweight are risk factors for TB recurrence [29][30][31][32] . However, we lacked information on these variables. ...

... There is growing evidence of an increased probability of COVID-19 in people with diabetes that may lead to hospitalization, organ failure, and premature mortality. 30 In TB patients and COVID-19 patients, the combination of malnutrition and low BMI is a major risk factor for early mortality. 31 ...

... Given the current burden of post-TB disease, morbidity and mortality, patients with TB would merit being assessed for general health status at the end of anti-TB treatment. We have previously argued that an end-of-treatment assessment needs to be carried out within the context of a national TB program (NTP), using a simple check list that documents on going symptoms, co-morbidities, social determinants and lung function, with appropriate actions taken if disability is identified [7,8]. However, most NTPs currently only focus on diagnosis and treatment. ...

... TB epidemiology in the Asia Pacific Region indicates a higher risk for males [67], but women often carry the burden of TB disease differently-through being the unpaid caretakers, having their healthcare deprioritized for the benefit of their male counterparts, and carrying a heavy burden of stigma associated with the disease [68]. In addition, in many high burden TB settings women also suffer from high rates of gender-based violence, HIV and other co-occurring biosocial phenomena [69,70]. ...

... If a pathological part of the body yields no symptoms, is it medically real? U.S. medicine prides itself on swift action (Ford, et al., 2020;, but when that's not possible, the path falls apart. Chronic-illness patients suffer from the uncertainty (Charmaz, 1983). ...

... In response to the growing evidence for a high burden of morbidity and mortality amongst TB-survivors, there have been calls from TB-affected groups, healthcare providers, and researchers for the development of clinical guidelines and programmatic standards for post-TB patient care [15][16][17][18]. However, there remain many barriers to implementation. ...

... This confirms the findings of a study on early access to BDQ performed in 2015, where lack of access to companion drugs was the most commonly reported countrylevel barrier [8]. Guaranteeing adequate procurement of affordable RR-TB drugs is thus essential to translate new policies and guidelines into practice and to accelerate the adoption of new advancements in TB care [53,54]. ...

... Inclusion of OR in the national strategic plan is important, because many donors including the Global Fund against AIDS, Tuberculosis and Malaria, do not fund interventions which are not a part of the national strategic plans. 19 Dedicated budgets will be required for paying salaries of personnel working on OR and their trainings, protocol development and ethics review, data collection (which may involve hiring additional people, travel, telecommunication expenses, hotel stay outside duty stations and per diem), data entry and analysis (which may require hiring of data entry operators or using computers and internet), dissemination of research findings nationally and internationally in conferences and publication in open access journals. All these processes cost money and these need to be budgeted. ...