Geraldine A. Tomlinson's scientific contributions

Publication (1)

Article
1. Glucuronide formation of bilirubin and p-nitrophenol in vitro with excess of UDP-glucuronic acid by UDP-glucuronyltransferase from livers of young and adult rabbits was studied. 2. The development of UDP-glucuronyltransferase for the two substrates followed a markedly different pattern during maturation of young rabbits, p-nitrophenol-conjugatio...

Citations

... This leads to the phenomenon of latency of UGT activity in preparations of ER (i.e., microsomes). The phenomenon of latency derives from experimental observations that in isolated microsomal preparations, UGTs generally show increased activities after the membranes are physically or chemically disrupted [20][21][22][23][24][25][26][27][28]. Other enzymes present in the lumen of the ER, such as glucose-6-phosphatase, also display latency [29]. ...