George Cloughley's research while affiliated with University College Dublin and other places
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Publications (3)
Although it is standard practice to replace fluid and electrolytes lost during vigorous exercise, replacement requirements seldom exist for minerals such as iodine. Iodine is an essential component for the production of thyroid hormones; hence, inadequate dietary intake leads to diminished thyroid hormone levels. On the basis of the published sweat...
5-Alkylidenecyclopent-2-enones 15a-q may be prepared via a conjugate addition-Peterson olefination sequence, best achieved in one-pot, using exo-2-trimethylsilyl-3a,4,7,7a-tetrahydro-4,7-methanoinden-1-one 12, followed by a retro-Diels-Alder reaction. The geometry of the exocyclic alkene may be controlled according to the use of organometallic spec...
Citations
... There is evidence that mild iodine deficiency can adversely affect cognitive function in children (31) and increase the risk of thyroid cancer in adults (32). A number of indices can be used to assess mild iodine deficiency in children, including thyroid volume, UIC, and Tg, for which exist validated and recommended cut-offs. ...
