Gabriella Cancemi's research while affiliated with Università degli Studi di Messina and other places

Publications (4)

Article
Full-text available
Aquaporins are transmembrane molecules regulating the transfer of water and other compounds such as ions, glycerol, urea, and hydrogen peroxide. Their alteration has been reported in several conditions such as cancer. Tumor progression might be enhanced by aquaporins in modifying tumor angiogenesis, cell volume adaptation, proteases activity, cell–...
Article
Full-text available
Liquid biopsy is one of the fastest emerging fields in cancer evaluation. Circulating tumour cells and tumour-originated DNA in plasma have become the new targets for their possible employ in tumour diagnosis, and liquid biopsy can define tumour burden without invasive procedures. Multiple Myeloma, one of the most frequent hematologic tumors, has b...
Article
Full-text available
Effectual cell-to-cell communication is essential to the development and differentiation of organisms, the preservation of tissue tasks, and the synchronization of their different physiological actions, but also to the proliferation and metastasis of tumor cells. Tunneling nanotubes (TNTs) are membrane-enclosed tubular connections between cells tha...

Citations

... Indeed, in the leukemic BM milieu, NADPH oxidase-2 (NOX2)-derived ROS stimulate mitochondrial transport between leukemic blasts and BM stromal cells via tunneling nanotubules, increasing metabolic alterations in AML cells [40] (Figure 2). Of particular interest is the result that the generation of ROS by leukemic cells appears quite different according to their type; this can play a role in the prognostic stratification of these patients. ...