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Effect size (ES) is a necessary complement to the statistical hypothesis testing, however, researchers rarely report ES in their papers. This work provides a conceptual review of the ES estimates for the difference between two means, taking into account the most important algorithms and their interpretation. We also provide a guide to the freely available and easy-to- use ViSta statistical software to compute ES. We hope this paper contributes to the diffusion of ES methods and encourages its use among researchers in Psychology.