G M Wassel's research while affiliated with National Research Center, Egypt and other places

Publications (25)

Article
Full-text available
An anticipated effect of khellin, related to its chemical structure, in the photochemotherapy of amelanosis has been investigated. In a double-blind clinical study, khellin has been orally administered to 30 vitiligo patients for 4 months with subsequent exposure to natural sunlight. At the end of the trial period, 5 patients out of 30 (16.6%) repi...
Article
The mucilages of certain organs of plants abundant in Egypt viz: seeds of Ceratonia siliqua L., Trigonella foenum-graecum L., Corchorus olitorius L., corms of Colocasia esculenta Schott. and fruits of Cordia myxa L. were studied. Each plant organ was pretreated to remove interfering substances and the extracted mucilage (by cold and hot methods) wa...
Article
The polysaccharides of stems of Opuntia ficusindica, seeds of Tamarindus indica and seeds of Cydonia oblonga were found to consist of a mixture of mucilage and pectin. The preparation of each polysaccharide could be achieved in an almost pure state. The mucilage could be extracted with cold acidulated water while the pectin was obtained by heating...
Article
Full-text available
The study of the nitrogenous bases of Onopordon alexandrinum Boiss. resulted on the isolation of stachydrine and choline. The flavonoid components detected are: Luteolin-7-monoglucoside, apigenin-7-glucoside and quercetin. © 1975, Verlag der Zeitschrift für Naturforschung. All rights reserved.
Article
Patulitrin was the only flavonoid component detected in the fruits ofProsopis juliflora D.C. The free sugar constituents of the fruits are glucose and sucrose.Patulitrin ist der einzige Flavonoid-Bestandteil inProsopis juliflora D.C. Frchten. Die freien Zucker sind Glucose und Saccharose.Patulitrin est la seule substance d'origine flavonique qui a...
Article
Extraction, separation and examination of the triterpenes from the alcoholic extract of Lantana camara L. was carried out using both column and thick layer chromatography after certain treatment, α–amyrin, β–sitosterol, lantadene B as well as an acidic triterpenoid substance, m. p. 130–131° C, were isolated. A lactone (m. p. 57° C) was isolated fro...
Article
A phtyochemical investigation of Lantana camara L. growing in Egypt was undertaken. The study of the lipids comprising both the fatty acids and the unsaponifiable matter was carried out revealing the presence of myristic, palmitic, arachidic, oleic and linoleic acids as well as α–amyrin, β–sitosterol and 1–triacontanol. The carbohydrates, examined...
Article
A phytochemical investigation of four Salsola species wildly grown in the Egyptian desert viz. S. tetrandra, S. kali, S. longifolia and S. rigida was undertaken. The study of the carbohydrates revealed the presence of fructose, glucose, arabinose and rhamnose in the four species. The study of the lipids of the four plants showed the presence of ole...
Article
The alkaloids of the most common Egyptian Salsola species were studied. Four bases were isolated from S. tetrandra: a major constituent, triacetonamine and two other minor bases as well as betaine. TLC showed that the same compounds were present in S. kali, S. longifolia and S. rigida.

Citations

... An old study revealed the presence of nitrogenous bases of Onopordum alexandrinum Boiss. and resulted in the isolation of stachydrine and choline and the detection of flavonoid components which were: Luteolin-7-monoglucoside, apigenin-7-glucoside and quercetin 13 . The compounds were assayed for their hepatoprotective activity against CCl4-induced hepatic cell damage in rats and free radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH) where acacetin-7-O-galacturonide has shown significant hepatoprotective and free radical scavenging effects 14 . ...
... [16] Chloroform/methanol extract of seeds was found active while ethanol (80%) extract of seeds was found inactive in anti fertility effect in female rats. [17] In female mice, however, anti fertility effect was found lies on petroleum ether extract of the seeds when administered Abrasine [9] Precatorine [10] Abrusoside A [11] Trigonelline [9] Delphinidin [12] Delphinidin-3-Sambubioside [13] ...
... Alkaloid extracts from Salsola species (Chenopodiaceae) have potential role in the treatment of Alzheimer's disease [Tundis R, 2009] [34] . Previous phytochemical investigation of the genus resulted in the isolation of alkaloids, saponins, sterols and their glucosides, comarinolignan, isoflavonoids, and flavonoids (Karawya et al, 1972;Wassell, et al 1979;Woldu and Abegaz, 1990;Syrchina et al, 1991;Oueslati et al, 2004;Oueslati et al, 2006;Xiang et al, 2007;Elsharabasy et al, 2013) [15,39,40,31,22,23,41,11] . Therefore, the present study deals with the identification of the phytochemical constituents of the hydro alcoholic extract from the aerial parts of S. tetrandra. ...
... Both mucilages and pectins are complex carbohydrate polymeric structures and form colloidal solutions in water. They differ from each other in terms of the chemical structure and physical properties (Karawya et al., 1980). Extraction of mucilages takes place using mild conditions and under neutral conditions; however, pectins require heating for 2 h at different pHs. ...
... Methanol extract of its root afforded 3 (137), pseudoginsenoside RT1 (129), and momordin II b (127) [68], in addition to nor-triterpene glycoside boussingoside A2 (135) [51,69,70]. Ethyl acetate soluble fraction of the alcoholic extract from their roots afforded an alkaloidal phenolic, N-transferuloyltyramine (103), in addition to isovanillic acid (83), ferulic acid (90) and p-hydroxy benzoic acid (71) [71]. Moreover, Bi-phenylpropanoids, named biphenylsalsonoid A (62) and biphenylsalsonoid B (61), were also isolated [72]. ...
... Also, many coumarin mixtures as well as alkaloids have been known in fenugreek roots (eg, trigonelline, carpaine, gentianine) [20]. The galactomannans observed in fenugreek have an individual construction and may be accountable for the amazing natural therapeutic characteristics connected to it [21]. ...
... Cordia myxa leaves contain coumarins, carotenoids, flavonoids, fatty acids, phenolic acids, pyrrolizidine alkaloids, saponins and sterols (Wassel et al. 1987;Miralles et al. 1989;Ficarra et al. 1995;Afzal et al. 2004;Pandey et al. 2014;Jasiem et al. 2016). Also, identification and characterization of hydrocolloids from C. myxa leaf were reported (Samavati et al. 2014). ...
... Previous preliminary phytochemical study of Z. spinosa revealed the presence of flavonoids, triterpenes and sterols [11], glucosinolates of free sinapine, progotrin [12] and goitrin [13]. Consequently, the aim of the present work is to evaluation of the medicinal uses of of Zilla spinosa. ...
... Quercetin, one of the major flavonoids of this plant, has been reported to inhibit the growth and development of malignant tumor cells due to their antioxidant behavior. Patulitrin is a novel flavonoid from the fruit and flower of this plant that has been reported to exert antitumor activity against lung carcinoma (Wassel, Rizk, and Abdel-Bary 1972). Along with these, naringenin, catechin, and kaempferol are the flavonoids that exert extremely efficient antioxidant behavior to the plant (Ruto et al. 2018). ...
... Various parts of this plant are used in folk medicine to treat urinary infections and the swelling of joints [16]. Chemical investigations on this plant are mainly confined to alkaloids and flavonoids [17][18][19][20][21]. Chemical analysis of leaf oil and its antibacterial activities are yet to be reported. ...