G. Fitch's research while affiliated with Leeds Teaching Hospitals NHS Trust and other places
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Publications (9)
The aetiology of increased serum bicarbonate and metabolic alkalosis in CF is complex and appears to be driven, at least in part, by renal tubular CFTR dysfunction https://bit.ly/3NFPkUu.
Objectives:
Cystic fibrosis arthropathy (CFA) is a term commonly used for joint pain with and without swelling seen in some patients with CF. Early studies into CFA focused on the presence of rheumatoid factor and immunological changes on synovial biopsy, with parallels drawn between respiratory and joint activity. Identification of anti-cyclic ci...
Background People with chronic health conditions use social media to share experiences and seek advice from peers. Similarly healthcare organisations are using these tools to engage and communicate with patients. The aim of this study was to investigate the opinions of health care professionals on the use, motives and impact of social media used by...
Objective
Cystic Fibrosis Arthropathy (CFA) is a term commonly used for joint pain +/– swelling seen in some patients. Early studies into CFA focused on presence of rheumatoid factor and immunological changes on synovial biopsy, with parallels drawn between respiratory and joint activity. Identification of anticyclic citrullinated peptide antibodie...
Objective
Procalcitonin (PCT), a precursor of calcitonin is selectively raised in bacterial infections. The aim of this pilot study was to investigate the role of PCT as a surrogate marker of infection in adults with CF and to discriminate between infection and inflammation in patients with elevated C reactive protein (CRP).
Methods
Adults with CF...
Objectives
Metabolic alkalosis is a recognised complication of CF. The condition appears to occur during both clinical stability and during pulmonary exacerbations. The aim of this study was to explore the relationship between metabolic alkalosis, clinical status and blood biochemistry.
Methods
A retrospective review of electronic patient records...
Objectives
Hypersensitivity reactions to beta-lactam antibiotics remain a major clinical problem in the management of patients with CF. Whilst reactions are more likely to occur in sicker patients receiving more frequent treatment this is not always the case and genetic predisposition may play a role.
Methods
Patients were recruited from the Leeds...
Citations
... The studies reporting on this campaign proved the positive of social media influencers on health promotion [16,17]. Moreover, a UK Survey conducted to investigate health care professional opinions on social media demonstrated that a percentage of 73.3% of responders considered social media as a negative instrument of communication [18]. Our experience is in contrast with this report. ...
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... Interestingly in our study, patients with spinal and/or joint pain were significantly shorter (167 ± 7 vs. 172 ± 9 cm, p = 0.023) and more frequently colonized with Staphylococcus aureus (91% vs. 56%, p < 0.008). The comparison is difficult with other specific studies concerning musculoskeletal and arthropathy in CF (6,13,36,37). In Roehmel et al. study involving 186 CF children and adults (mean age: 27 years), patients with CFA (defined as at least one symptom out of the following: joint pain, joint swelling, joint reddening or limitation of movement) were more likely to be older, female gender, and to have a higher rate of total IgG, chronic colonization with Aspergillus spp. ...
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